iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033271

UUCD1 version

UUC-EqC-01029

Ensembl Protein ID

ENSECAP00000015004.1

UniProt Accession

F6PT23; F6PT23_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000016603.1	ENSECAT00000018394.1	ENSECAP00000015004.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.30e-112	375.2	256	877

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+ ++ e+ln  np ++kge+++++++l+++ w+++++++ p+ ++++++++a++f gy+
   Q: 256  CGLTNLGNTCFMNSALQCLSNVPQLTEYFLKnRYLEELNFCNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKTKVGHFASQFLGYQ 344
           7*****************************999******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           q+D+qE+l+flld+l+e+l++ k+k++ e+++++ +  ++    a++++k++n+s+i+d+F+g +ks+++c++c+nvs++++pf++ls+
   Q: 345  QHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVaqeAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSV 433
           *****************************998874333322555********************************************* PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++++ +e                                                                              
   Q: 434  PLPVSHKRVMEvffvsmdprrkpeqhrlvvpkkgkisdlcvalakhtgvspermmvadvfshrfykiyqleeslssildrddifiyevs 522
           ******99988****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 523  grsaigensredvvlpiylrertpardynnsyyglmlfghpllvsvprdrlswdalyhillyrlsryvtrpssddeddgdekdledkdn 611
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 612  ipkpghvaggssqdpgpeqagpssgvaggsrapvdnsagpshwpqrarrkhlftlqtvnsngtsdrstfnedthaqpyiaidwepemkk 700
           ***************************************************************************************** PP
   S: 186  ..........................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
                                      lq+c+e ft+ e+le+en +yc++ck++q a+kkl+l+ lPe+Li+hLkRfs+++   srek
   Q: 701  ryydeveaegyvkhdcvgyvlkkapvRLQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPETLIIHLKRFSYTK--FSREK 787
           ******************************************************************************8866..89*** PP
   S: 249  inkkvefple.Ldlspfctspeekqke.kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlf 334
           +++ vefp++ Ld s+f+++p+++++   +kY+Liav +H+G+l+ GHY++++ n ++g+W +fdDs+V++v+e+++++   + aYvlf
   Q: 788  LDTLVEFPIRdLDFSEFVIKPQNESAPeLYKYDLIAVSNHYGGLRDGHYTTFACNkDSGQWHYFDDSSVSPVTENQIES---KAAYVLF 873
           ******************999887754489*********************988834566*******************...******* PP
   S: 335  Ykrr 338
           Y+r+
   Q: 874  YQRQ 877
           **96 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAAVAADPAA VDAAEDREPQ RKAVPGLESQ RRQIKSSESG RERPLRAGES WFLVEQHWYQ 60
QWELYVQGGD QDSSTFPGCI NNAKLFEDQV NWRLKKGLVE GEDYVLLPEA AWHYLVSWYG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCAG TCGCAGCAGA TCCGGCGGCT GTGGATGCGG CCGAGGACCG AGAGCCACAG 60
CGCAAAGCCG TGCCGGGCCT GGAGAGCCAG CGGCGCCAGA TCAAGAGCAG CGAGAGTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	92.93	0.00e+00	1694.00
IUUC-Atr-002675	Amborella trichopoda	39.21	3.00e-105	376.00
IUUC-Aca-004532	Anolis carolinensis	66.48	0.00e+00	1157.00
IUUC-Afl-008507	Aspergillus flavus	35.08	3.00e-54	207.00
IUUC-Afu-008878	Aspergillus fumigatus	36.49	2.00e-56	214.00
IUUC-Aor-009949	Aspergillus oryzae	34.85	3.00e-53	204.00
IUUC-Ate-010323	Aspergillus terreus	37.14	2.00e-57	218.00
IUUC-Bta-013284	Bos taurus	92.18	0.00e+00	1634.00
IUUC-Cja-019746	Callithrix jacchus	83.52	0.00e+00	1503.00
IUUC-Cfa-020134	Canis familiaris	94.01	0.00e+00	1707.00
IUUC-Cpo-022535	Cavia porcellus	77.53	0.00e+00	1459.00
IUUC-Csa-023828	Chlorocebus sabaeus	84.30	0.00e+00	1541.00
IUUC-Dre-027398	Danio rerio	62.52	0.00e+00	749.00
IUUC-Dno-028853	Dasypus novemcinctus	88.32	0.00e+00	1393.00
IUUC-Dor-030384	Dipodomys ordii	80.72	0.00e+00	1457.00
IUUC-Dse-031432	Dothistroma septosporum	36.36	2.00e-58	221.00
IUUC-Fca-036012	Felis catus	93.76	0.00e+00	1722.00
IUUC-Fso-038291	Fusarium solani	44.49	2.00e-64	241.00
IUUC-Gac-042574	Gasterosteus aculeatus	55.82	0.00e+00	911.00
IUUC-Hsa-046551	Homo sapiens	84.30	0.00e+00	1540.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	80.42	0.00e+00	1451.00
IUUC-Kpa-049332	Komagataella pastoris	34.39	3.00e-70	260.00
IUUC-Laf-054561	Loxodonta africana	86.41	0.00e+00	1605.00
IUUC-Mcc-054881	Macaca mulatta	83.96	0.00e+00	1539.00
IUUC-Meu-056749	Macropus eugenii	83.21	0.00e+00	926.00
IUUC-Mla-058848	Melampsora laricipopulina	41.99	1.00e-72	268.00
IUUC-Mvi-060324	Microbotryum violaceum	32.15	2.00e-80	295.00
IUUC-Mmr-061400	Microcebus murinus	85.84	0.00e+00	1575.00
IUUC-Mmu-063241	Mus musculus	76.54	0.00e+00	1418.00
IUUC-Mpu-066507	Mustela putorius furo	94.10	0.00e+00	1735.00
IUUC-Mlu-066961	Myotis lucifugus	84.00	0.00e+00	1519.00
IUUC-Nfi-068330	Neosartorya fischeri	38.46	3.00e-55	211.00
IUUC-Nle-069284	Nomascus leucogenys	84.30	0.00e+00	1543.00
IUUC-Ont-071847	Oreochromis niloticus	58.57	0.00e+00	989.00
IUUC-Oan-073387	Ornithorhynchus anatinus	72.37	0.00e+00	1245.00
IUUC-Ocu-074066	Oryctolagus cuniculus	84.47	0.00e+00	1512.00
IUUC-Oga-088424	Otolemur garnettii	85.19	0.00e+00	1543.00
IUUC-Oar-089732	Ovis aries	89.47	0.00e+00	1620.00
IUUC-Pan-092292	Papio anubis	83.96	0.00e+00	1536.00
IUUC-Pab-098779	Pongo abelii	76.27	0.00e+00	1319.00
IUUC-Pca-100851	Procavia capensis	86.71	0.00e+00	922.00
IUUC-Pva-103244	Pteropus vampyrus	91.31	0.00e+00	1639.00
IUUC-Ptt-103847	Puccinia triticina	36.29	2.00e-64	241.00
IUUC-Rno-105100	Rattus norvegicus	77.84	0.00e+00	1422.00
IUUC-Sce-106170	Saccharomyces cerevisiae	36.08	2.00e-60	227.00
IUUC-Sha-107502	Sarcophilus harrisii	80.97	0.00e+00	915.00
IUUC-Spo-108291	Schizosaccharomyces pombe	32.22	4.00e-74	273.00
IUUC-Smo-109356	Selaginella moellendorffii	39.41	4.00e-115	408.00
IUUC-Sar-113704	Sorex araneus	75.99	0.00e+00	793.00
IUUC-Ssc-116345	Sus scrofa	93.57	0.00e+00	1720.00
IUUC-Tru-117788	Takifugu rubripes	58.38	0.00e+00	943.00
IUUC-Tsy-119414	Tarsius syrichta	77.78	0.00e+00	1092.00
IUUC-Tre-121888	Trichoderma reesei	36.49	2.00e-63	238.00
IUUC-Tvi-122422	Trichoderma virens	41.91	5.00e-58	220.00
IUUC-Tme-127062	Tuber melanosporum	34.48	2.00e-80	294.00
IUUC-Tbe-128081	Tupaia belangeri	87.69	0.00e+00	994.00
IUUC-Ttr-128502	Tursiops truncatus	90.65	0.00e+00	1635.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence