iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000004955.5	ENSCAFT00000007959.5	ENSCAFP00000007370.4
ENSCAFG00000004955.5	ENSCAFT00000046455.1	ENSCAFP00000040975.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-18	67.1	886	936

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek.slveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C vCg+ g++ +  l+ C++C +++Hp C+++++ + + ++  w C +C+
   Q: 886  DMCVVCGSFGQGAEgRLLACSQCGQCYHPYCVSIKITKVVLSK-GWRCLECT 936
           79*********9999********************66666555.5******6 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDGLETTETE NIVETEIKEQ SAEEDAEAEV DNSKRPIPVL QRSVSEESAS SLVSVGVEAK 60
ISEQLCAFCY CGEKSSLGQG DLKQFRVTPG FILPWKSQPS NKKDVDDNSN GTCERIQNSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTCGGAGT AAAGGAAAAA CTACCGTGGA AGATGAGGAC AGCATGGATG GACTGGAGAC 60
AACAGAAACA GAAAATATTG TGGAAACAGG TACCAAAGTT AACAGAATTT TTAAAATGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	93.73	0.00e+00	7852.00
IUUC-Apl-003311	Anas platyrhynchos	71.36	0.00e+00	5710.00
IUUC-Aca-004705	Anolis carolinensis	64.68	0.00e+00	5244.00
IUUC-Bta-012322	Bos taurus	83.86	0.00e+00	6886.00
IUUC-Cel-018354	Caenorhabditis elegans	35.67	2.00e-64	242.00
IUUC-Cja-019983	Callithrix jacchus	86.98	0.00e+00	7434.00
IUUC-Cpo-021732	Cavia porcellus	81.44	0.00e+00	6848.00
IUUC-Csa-023083	Chlorocebus sabaeus	85.37	0.00e+00	5597.00
IUUC-Cho-024469	Choloepus hoffmanni	82.21	0.00e+00	2338.00
IUUC-Dre-028110	Danio rerio	63.79	0.00e+00	1229.00
IUUC-Dor-030569	Dipodomys ordii	78.71	0.00e+00	4474.00
IUUC-Dme-031590	Drosophila melanogaster	33.60	4.00e-69	257.00
IUUC-Eca-033945	Equus caballus	88.28	0.00e+00	5409.00
IUUC-Fca-035922	Felis catus	89.43	0.00e+00	7426.00
IUUC-Gac-041896	Gasterosteus aculeatus	45.19	0.00e+00	1810.00
IUUC-Ggo-044812	Gorilla gorilla	84.79	0.00e+00	7270.00
IUUC-Hsa-046595	Homo sapiens	87.25	0.00e+00	7438.00
IUUC-Itr-048303	Ictidomys tridecemlineatus	84.17	0.00e+00	6947.00
IUUC-Lch-050086	Latimeria chalumnae	55.70	0.00e+00	2607.00
IUUC-Loc-052891	Lepisosteus oculatus	51.55	0.00e+00	2148.00
IUUC-Laf-054348	Loxodonta africana	84.15	0.00e+00	3158.00
IUUC-Mcc-054868	Macaca mulatta	87.60	0.00e+00	7419.00
IUUC-Meu-056322	Macropus eugenii	65.91	0.00e+00	1189.00
IUUC-Mga-059541	Meleagris gallopavo	71.25	0.00e+00	5606.00
IUUC-Mmr-061092	Microcebus murinus	85.10	0.00e+00	5574.00
IUUC-Mdo-062610	Monodelphis domestica	74.29	0.00e+00	2016.00
IUUC-Mmu-063666	Mus musculus	82.63	0.00e+00	6859.00
IUUC-Mpu-066366	Mustela putorius furo	90.28	0.00e+00	7227.00
IUUC-Mlu-068201	Myotis lucifugus	83.55	0.00e+00	4321.00
IUUC-Nle-069232	Nomascus leucogenys	85.21	0.00e+00	5577.00
IUUC-Opr-070625	Ochotona princeps	72.96	0.00e+00	1238.00
IUUC-Ont-072401	Oreochromis niloticus	57.36	0.00e+00	1051.00
IUUC-Oan-072945	Ornithorhynchus anatinus	71.03	0.00e+00	4151.00
IUUC-Ocu-074920	Oryctolagus cuniculus	81.76	0.00e+00	5346.00
IUUC-Ola-086436	Oryzias latipes	44.11	0.00e+00	1795.00
IUUC-Oga-088637	Otolemur garnettii	82.41	0.00e+00	4429.00
IUUC-Oar-089363	Ovis aries	81.58	0.00e+00	6693.00
IUUC-Ptr-091527	Pan troglodytes	87.17	0.00e+00	7509.00
IUUC-Pan-092102	Papio anubis	85.21	0.00e+00	7138.00
IUUC-Pma-094252	Petromyzon marinus	40.23	0.00e+00	657.00
IUUC-Pfo-096288	Poecilia formosa	48.03	0.00e+00	1560.00
IUUC-Pab-098241	Pongo abelii	87.72	0.00e+00	4885.00
IUUC-Pca-100103	Procavia capensis	78.36	0.00e+00	1518.00
IUUC-Pva-102238	Pteropus vampyrus	79.59	0.00e+00	2737.00
IUUC-Rno-105395	Rattus norvegicus	70.03	0.00e+00	1036.00
IUUC-Sha-106550	Sarcophilus harrisii	71.62	0.00e+00	4470.00
IUUC-Sar-113183	Sorex araneus	66.47	0.00e+00	681.00
IUUC-Tgu-116677	Taeniopygia guttata	70.31	0.00e+00	5376.00
IUUC-Tru-118037	Takifugu rubripes	47.16	0.00e+00	1472.00
IUUC-Tsy-118932	Tarsius syrichta	86.50	0.00e+00	5321.00
IUUC-Tni-119970	Tetraodon nigroviridis	47.18	0.00e+00	1415.00
IUUC-Ttr-129051	Tursiops truncatus	84.64	0.00e+00	6776.00
IUUC-Vpa-130236	Vicugna pacos	84.81	0.00e+00	2050.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence