iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062619

UUCD1 version

UUC-MoD-00314

Ensembl Protein ID

ENSMODP00000002374.3

UniProt Accession

F6VJS6; F6VJS6_MONDO

Protein Name

Uncharacterized protein

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001948.3	ENSMODT00000002424.3	ENSMODP00000002374.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.60e-43	142.5	193	234
UBD/Beta-Prp	2.10e-54	184.9	147	352

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllks 38
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++s
   Q: 193  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCIQS 234
           8***********9644499********************986 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 147  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCIQ-S 234
           567889999*********99***************************************9777************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 235  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 323
           ******************************************95333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++r+W
   Q: 324  HENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
           ***************************** PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAAEGLHESE TLASLKSEAE SLKSRLEEER AKLHDVELHQ VAERVEALGQ FVMKTRRTLK 60
GHGNKVLCMD WCKDKRRIVS SSQDGKVIVW DSFTTNKEHA VTMPCTWVMA CAYAPSGCAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGAGCAAG ATCAAGGATC TGCTGCGGCC CAAATTGGTC CTTACCAGAG CATCACGCCC 60
TGGGCGTGGC TGGGAGGCAG GGCCTCTGTC TAAGGTCTCC AGTACCTTAG GGACCGCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	91.22	0.00e+00	677.00
IUUC-Apl-003399	Anas platyrhynchos	99.36	0.00e+00	653.00
IUUC-Aca-004861	Anolis carolinensis	96.88	0.00e+00	717.00
IUUC-Ame-011851	Astyanax mexicanus	92.88	0.00e+00	692.00
IUUC-Bta-012438	Bos taurus	98.02	0.00e+00	725.00
IUUC-Cel-018408	Caenorhabditis elegans	64.93	6.00e-140	490.00
IUUC-Cja-019086	Callithrix jacchus	98.29	0.00e+00	722.00
IUUC-Cfa-021255	Canis familiaris	99.38	0.00e+00	674.00
IUUC-Cpo-021398	Cavia porcellus	96.61	0.00e+00	714.00
IUUC-Csa-023776	Chlorocebus sabaeus	98.02	0.00e+00	725.00
IUUC-Cin-025305	Ciona intestinalis	58.20	3.00e-132	464.00
IUUC-Csv-026058	Ciona savignyi	57.87	1.00e-128	452.00
IUUC-Dre-028572	Danio rerio	90.70	0.00e+00	683.00
IUUC-Dno-029958	Dasypus novemcinctus	83.47	2.00e-119	421.00
IUUC-Dor-031013	Dipodomys ordii	98.44	4.00e-153	533.00
IUUC-Dme-031889	Drosophila melanogaster	68.12	3.00e-149	521.00
IUUC-Eca-033977	Equus caballus	93.43	0.00e+00	682.00
IUUC-Eeu-035079	Erinaceus europaeus	97.17	0.00e+00	721.00
IUUC-Fca-035693	Felis catus	91.48	0.00e+00	672.00
IUUC-Fal-037345	Ficedula albicollis	97.45	0.00e+00	723.00
IUUC-Gmo-039222	Gadus morhua	91.50	0.00e+00	662.00
IUUC-Gga-040320	Gallus gallus	98.02	0.00e+00	725.00
IUUC-Gac-042644	Gasterosteus aculeatus	91.22	0.00e+00	688.00
IUUC-Ggo-044489	Gorilla gorilla	93.79	0.00e+00	686.00
IUUC-Hsa-046434	Homo sapiens	98.30	0.00e+00	726.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	93.04	1.00e-176	612.00
IUUC-Loc-052790	Lepisosteus oculatus	96.00	0.00e+00	678.00
IUUC-Laf-054255	Loxodonta africana	96.58	0.00e+00	711.00
IUUC-Mcc-055610	Macaca mulatta	98.01	0.00e+00	719.00
IUUC-Meu-056819	Macropus eugenii	97.44	0.00e+00	630.00
IUUC-Mga-059740	Meleagris gallopavo	91.81	0.00e+00	668.00
IUUC-Mmr-061221	Microcebus murinus	97.45	0.00e+00	722.00
IUUC-Mmu-064266	Mus musculus	97.73	0.00e+00	724.00
IUUC-Mpu-065766	Mustela putorius furo	98.67	0.00e+00	627.00
IUUC-Mlu-067221	Myotis lucifugus	91.22	0.00e+00	671.00
IUUC-Nle-069515	Nomascus leucogenys	99.05	0.00e+00	660.00
IUUC-Opr-070195	Ochotona princeps	88.67	0.00e+00	637.00
IUUC-Ont-071535	Oreochromis niloticus	83.00	7.00e-160	556.00
IUUC-Oan-072899	Ornithorhynchus anatinus	98.92	7.00e-108	382.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.00	0.00e+00	629.00
IUUC-Ola-086578	Oryzias latipes	92.33	0.00e+00	653.00
IUUC-Oga-089090	Otolemur garnettii	97.18	0.00e+00	718.00
IUUC-Oar-090017	Ovis aries	92.57	0.00e+00	666.00
IUUC-Ptr-091280	Pan troglodytes	99.05	0.00e+00	662.00
IUUC-Pan-092198	Papio anubis	98.43	0.00e+00	660.00
IUUC-Psi-093030	Pelodiscus sinensis	90.65	0.00e+00	671.00
IUUC-Pma-094140	Petromyzon marinus	88.30	5.00e-89	320.00
IUUC-Pfo-097182	Poecilia formosa	92.07	0.00e+00	666.00
IUUC-Pab-098157	Pongo abelii	98.30	0.00e+00	729.00
IUUC-Pca-100988	Procavia capensis	73.94	3.00e-143	501.00
IUUC-Pva-102232	Pteropus vampyrus	84.86	1.00e-174	605.00
IUUC-Rno-105526	Rattus norvegicus	94.08	0.00e+00	687.00
IUUC-Sce-106298	Saccharomyces cerevisiae	35.38	1.00e-67	249.00
IUUC-Sha-106754	Sarcophilus harrisii	99.43	0.00e+00	685.00
IUUC-Ssc-115390	Sus scrofa	98.02	0.00e+00	721.00
IUUC-Tgu-117377	Taeniopygia guttata	98.42	0.00e+00	654.00
IUUC-Tru-117938	Takifugu rubripes	92.35	0.00e+00	654.00
IUUC-Tsy-119392	Tarsius syrichta	82.72	5.00e-167	580.00
IUUC-Tni-119834	Tetraodon nigroviridis	76.49	5.00e-154	536.00
IUUC-Tbe-127469	Tupaia belangeri	95.71	0.00e+00	684.00
IUUC-Ttr-128252	Tursiops truncatus	97.17	0.00e+00	713.00
IUUC-Vpa-130173	Vicugna pacos	90.62	1.00e-137	483.00
IUUC-Xtr-131803	Xenopus tropicalis	96.60	0.00e+00	678.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence