iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.60e-06	26.8	92	132

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C iC+ +f   + ++ lpC H++h +C+  w        ++ +CP C
   Q: 92   CVICMAEFcvNEAVRYLPCMHIYHVNCIDDW------LLRSLTCPSC 132
           ********99555******************......999******* PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MGNCLKISTS DDISLLRGND SQISGTQPVY HQGEHYQREL YPSTSSSTTL TPSSNNRQLS 60
DENQVKIAKR IGLMQYLPIG TYDGSSKKAR ECVICMAEFC VNEAVRYLPC MHIYHVNCID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCACTGTTGA TTTTGGTTTA TTTATTGTCA AATAGGTAAA AAGTCTAAGC ATATGGAATA 60
AATCAGGCTT TATTAAATCG AATCTAGTCT AATTTCAAAG AAAGTCACAT TTAATGTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001762	Ailuropoda melanoleuca	51.63	2.00e-38	150.00
IUUC-Apl-003879	Anas platyrhynchos	65.59	1.00e-35	140.00
IUUC-Aca-004887	Anolis carolinensis	50.98	3.00e-38	149.00
IUUC-Aly-005951	Arabidopsis lyrata	43.84	5.00e-12	63.20
IUUC-Ame-011317	Astyanax mexicanus	51.95	4.00e-39	152.00
IUUC-Bta-013543	Bos taurus	65.59	1.00e-35	140.00
IUUC-Cel-018152	Caenorhabditis elegans	35.10	2.00e-22	97.10
IUUC-Cja-019172	Callithrix jacchus	50.98	2.00e-38	150.00
IUUC-Cfa-020423	Canis familiaris	65.59	2.00e-35	140.00
IUUC-Cpo-021457	Cavia porcellus	50.98	2.00e-38	150.00
IUUC-Csa-024165	Chlorocebus sabaeus	50.98	2.00e-38	150.00
IUUC-Cho-024439	Choloepus hoffmanni	65.59	1.00e-35	141.00
IUUC-Cin-025246	Ciona intestinalis	69.49	7.00e-23	97.10
IUUC-Csv-026239	Ciona savignyi	56.04	2.00e-29	120.00
IUUC-Dre-027392	Danio rerio	47.93	2.00e-38	150.00
IUUC-Dno-029468	Dasypus novemcinctus	65.59	1.00e-35	140.00
IUUC-Dor-030265	Dipodomys ordii	50.98	2.00e-38	150.00
IUUC-Ete-032526	Echinops telfairi	50.98	2.00e-38	150.00
IUUC-Eca-033516	Equus caballus	65.59	1.00e-35	140.00
IUUC-Eeu-035261	Erinaceus europaeus	65.59	1.00e-35	140.00
IUUC-Fca-036029	Felis catus	50.98	2.00e-38	150.00
IUUC-Fal-036620	Ficedula albicollis	65.59	1.00e-35	140.00
IUUC-Gmo-038539	Gadus morhua	53.90	1.00e-38	151.00
IUUC-Gga-040240	Gallus gallus	50.98	3.00e-38	149.00
IUUC-Gac-041863	Gasterosteus aculeatus	48.52	1.00e-38	150.00
IUUC-Ggo-045517	Gorilla gorilla	50.98	2.00e-38	150.00
IUUC-Hsa-046313	Homo sapiens	50.98	2.00e-38	150.00
IUUC-Itr-048979	Ictidomys tridecemlineatus	50.33	5.00e-38	149.00
IUUC-Lch-050201	Latimeria chalumnae	52.67	1.00e-34	137.00
IUUC-Lpe-050757	Leersia perrieri	42.19	2.00e-12	64.70
IUUC-Loc-052731	Lepisosteus oculatus	54.49	5.00e-38	149.00
IUUC-Laf-053374	Loxodonta africana	65.59	1.00e-35	140.00
IUUC-Mcc-055336	Macaca mulatta	50.98	2.00e-38	150.00
IUUC-Meu-055960	Macropus eugenii	64.52	5.00e-35	138.00
IUUC-Mla-059167	Melampsora laricipopulina	38.60	6.00e-08	52.00
IUUC-Mga-059363	Meleagris gallopavo	65.59	1.00e-35	140.00
IUUC-Mmr-061651	Microcebus murinus	50.98	2.00e-38	150.00
IUUC-Mdo-062554	Monodelphis domestica	62.77	2.00e-34	137.00
IUUC-Mmu-064330	Mus musculus	50.98	2.00e-38	150.00
IUUC-Mpu-065844	Mustela putorius furo	50.98	2.00e-38	150.00
IUUC-Mlu-067557	Myotis lucifugus	50.98	2.00e-38	150.00
IUUC-Nle-069160	Nomascus leucogenys	65.59	1.00e-35	140.00
IUUC-Opr-070708	Ochotona princeps	48.37	2.00e-35	140.00
IUUC-Ont-071784	Oreochromis niloticus	47.65	2.00e-38	150.00
IUUC-Oan-073071	Ornithorhynchus anatinus	65.59	1.00e-35	140.00
IUUC-Ocu-074236	Oryctolagus cuniculus	50.98	2.00e-38	150.00
IUUC-Oin-079252	Oryza indica	44.44	4.00e-10	59.30
IUUC-Ola-087427	Oryzias latipes	52.60	1.00e-40	157.00
IUUC-Oga-088630	Otolemur garnettii	45.00	6.00e-30	122.00
IUUC-Oar-089615	Ovis aries	50.98	2.00e-38	150.00
IUUC-Ptr-091459	Pan troglodytes	50.98	2.00e-38	150.00
IUUC-Pan-092848	Papio anubis	50.98	2.00e-38	150.00
IUUC-Psi-092968	Pelodiscus sinensis	50.98	3.00e-38	149.00
IUUC-Pfo-096033	Poecilia formosa	52.26	6.00e-41	159.00
IUUC-Pab-098483	Pongo abelii	50.98	2.00e-38	150.00
IUUC-Pop-099512	Populus trichocarpa	47.54	1.00e-11	61.60
IUUC-Pca-100978	Procavia capensis	70.91	3.00e-22	96.70
IUUC-Ppe-101991	Prunus persica	47.54	5.00e-11	59.70
IUUC-Pva-102550	Pteropus vampyrus	50.98	2.00e-38	150.00
IUUC-Rno-105946	Rattus norvegicus	51.97	3.00e-38	149.00
IUUC-Sha-106723	Sarcophilus harrisii	64.52	5.00e-35	138.00
IUUC-Sly-111550	Solanum lycopersicum	49.12	1.00e-11	61.60
IUUC-Stu-112368	Solanum tuberosum	46.97	6.00e-12	62.80
IUUC-Sar-113209	Sorex araneus	50.98	2.00e-38	150.00
IUUC-Ssc-115813	Sus scrofa	50.98	2.00e-38	150.00
IUUC-Tgu-117220	Taeniopygia guttata	65.59	1.00e-35	140.00
IUUC-Tru-118754	Takifugu rubripes	49.70	5.00e-39	152.00
IUUC-Tsy-118863	Tarsius syrichta	65.59	1.00e-35	140.00
IUUC-Tni-119702	Tetraodon nigroviridis	49.11	6.00e-39	152.00
IUUC-Tca-120911	Theobroma cacao	43.59	2.00e-11	62.00
IUUC-Tur-126708	Triticum urartu	40.21	3.00e-12	63.90
IUUC-Tbe-127266	Tupaia belangeri	39.18	2.00e-09	53.10
IUUC-Ttr-128337	Tursiops truncatus	50.98	2.00e-38	150.00
IUUC-Vpa-130786	Vicugna pacos	65.59	1.00e-35	140.00
IUUC-Vvi-131731	Vitis vinifera	43.90	3.00e-12	64.30
IUUC-Xtr-132840	Xenopus tropicalis	50.98	2.00e-38	150.00
IUUC-Xma-133381	Xiphophorus maculatus	52.26	6.00e-41	159.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence