iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117368

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01033436

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000012279.1	ENSTGUT00000012789.1	ENSTGUP00000012648.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.40e-09	36.6	804	848

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gg+    l++CekC ++fH  C+ ++   ++p+ e wiC+ Cr
   Q: 804  DWCAVCQNGGK----LLCCEKCPKVFHLSCHVPT-LMSFPSGE-WICTFCR 848
           79*********....*******************.*******8.******8 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

GAAAALSGEN EAESRQGPAE RGGDAAPLNL LDTCGVCGQP IQSRQPKLLP CLHSVCQRCL 60
PQPDRYLMLP PVLTPAAAAA LKEPPPAAPP SSPVSSQASA MHCTPISVIR CPICGQDCAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCCGCGG CGGCGCTGAG CGGGGAGAAC GAAGCCGAGA GCCGTCAGGG CCCGGCGGAG 60
CGCGGCGGGG ACGCGGCCCC GCTCAACCTG TTGGACACTT GCGGCGTGTG CGGGCAGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS00518--ZF_RING_1

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	77.30	0.00e+00	1357.00
IUUC-Apl-003697	Anas platyrhynchos	89.62	0.00e+00	1467.00
IUUC-Bta-013282	Bos taurus	77.18	0.00e+00	1385.00
IUUC-Cel-018225	Caenorhabditis elegans	21.70	8.00e-15	75.90
IUUC-Cja-018920	Callithrix jacchus	76.89	0.00e+00	1402.00
IUUC-Cfa-020984	Canis familiaris	77.59	0.00e+00	1396.00
IUUC-Cpo-022035	Cavia porcellus	78.24	0.00e+00	1333.00
IUUC-Csa-024208	Chlorocebus sabaeus	77.79	0.00e+00	1415.00
IUUC-Dno-029145	Dasypus novemcinctus	79.42	0.00e+00	1342.00
IUUC-Dor-030396	Dipodomys ordii	75.56	0.00e+00	979.00
IUUC-Ete-032414	Echinops telfairi	75.12	0.00e+00	775.00
IUUC-Eca-033489	Equus caballus	79.94	0.00e+00	1316.00
IUUC-Eeu-034654	Erinaceus europaeus	73.03	1.00e-165	576.00
IUUC-Fca-035844	Felis catus	76.66	0.00e+00	1192.00
IUUC-Fal-036735	Ficedula albicollis	94.58	0.00e+00	1596.00
IUUC-Gga-041124	Gallus gallus	87.34	0.00e+00	1578.00
IUUC-Ggo-044542	Gorilla gorilla	77.69	0.00e+00	1413.00
IUUC-Hsa-046785	Homo sapiens	77.57	0.00e+00	1409.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	78.03	0.00e+00	1365.00
IUUC-Laf-054279	Loxodonta africana	76.80	0.00e+00	1377.00
IUUC-Mcc-055668	Macaca mulatta	77.69	0.00e+00	1413.00
IUUC-Meu-056195	Macropus eugenii	68.79	0.00e+00	691.00
IUUC-Mga-059272	Meleagris gallopavo	88.32	0.00e+00	1436.00
IUUC-Mmr-060936	Microcebus murinus	76.92	0.00e+00	1391.00
IUUC-Mdo-062848	Monodelphis domestica	79.05	0.00e+00	1413.00
IUUC-Mmu-063598	Mus musculus	76.50	0.00e+00	1359.00
IUUC-Mpu-066272	Mustela putorius furo	79.55	0.00e+00	1301.00
IUUC-Mlu-067958	Myotis lucifugus	78.16	0.00e+00	1313.00
IUUC-Nle-069375	Nomascus leucogenys	77.69	0.00e+00	1413.00
IUUC-Oan-073393	Ornithorhynchus anatinus	77.06	0.00e+00	932.00
IUUC-Ocu-074873	Oryctolagus cuniculus	76.84	0.00e+00	1301.00
IUUC-Ola-086481	Oryzias latipes	53.56	6.00e-130	458.00
IUUC-Oga-088692	Otolemur garnettii	77.13	0.00e+00	1368.00
IUUC-Oar-090160	Ovis aries	79.08	0.00e+00	1305.00
IUUC-Ptr-090756	Pan troglodytes	77.57	0.00e+00	1409.00
IUUC-Pan-091719	Papio anubis	77.69	0.00e+00	1412.00
IUUC-Psi-093433	Pelodiscus sinensis	84.16	0.00e+00	1405.00
IUUC-Pma-094506	Petromyzon marinus	61.36	2.00e-49	186.00
IUUC-Pfo-097104	Poecilia formosa	55.04	2.00e-127	449.00
IUUC-Pab-098599	Pongo abelii	76.53	0.00e+00	1384.00
IUUC-Pca-100540	Procavia capensis	75.32	0.00e+00	811.00
IUUC-Pva-102478	Pteropus vampyrus	72.07	0.00e+00	1233.00
IUUC-Sha-106740	Sarcophilus harrisii	76.60	0.00e+00	1249.00
IUUC-Sar-113615	Sorex araneus	76.58	0.00e+00	1116.00
IUUC-Tsy-118904	Tarsius syrichta	78.73	0.00e+00	1320.00
IUUC-Tbe-127354	Tupaia belangeri	64.52	2.00e-151	529.00
IUUC-Ttr-128983	Tursiops truncatus	74.86	0.00e+00	944.00
IUUC-Vpa-130420	Vicugna pacos	78.41	0.00e+00	1285.00
IUUC-Xtr-132822	Xenopus tropicalis	63.18	0.00e+00	1008.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence