iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020129

Ensembl Protein ID

ENSCAFP00000028429.3

UniProt Accession

F1PXQ7; F1PXQ7_CANLF

Genbank Protein ID

ENSCAFP00000028429

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03004591

Gene Name

SLX4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000019268.3	ENSCAFT00000030592.3	ENSCAFP00000028429.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/UBZ	1.50e-06	28.7	225	250

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/UBZ

   S: 2    lvCPvC...qkmvdqtdfeeHlDeCl 24
           ++C++C    +++++t++e+H+++Cl
   Q: 225  FFCQIChknLSAMNVTRREQHVNRCL 250
           89****655555*************8 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDESDDDFKE LCASFLQRVK KNVSKEVLGE RKGQKASNST QISKPKRTKP TGTRGKTLPG 60
PREKKTWSGS QAPRTKEQGA PKQQESEPAP PKNGEGSVLA STPLQKGAQT TQTEAAPDSN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTTCCTCTT GTGTTGTGTT GTGATAAACT CCCCATGAGT TTGTTGTCAA CCAGGCTGTA 60
CCTGAGTATT TGACACAGGT ATTGTTATTC TGAGGACTTT GCCCATACTC CACATCCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR018574--Structure-sp_endonuc_su_Slx4

PROSITE

PS50097--BTB

Pfam

PF00651--BTB
PF09494--Slx4

SMART

SM00225--BTB

Gene Ontology

GO:0030054--C:cell junction
GO:0005829--C:cytosol
GO:0070522--C:ERCC4-ERCC1 complex
GO:0048476--C:Holliday junction resolvase complex
GO:0000790--C:nuclear chromatin
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0033557--C:Slx1-Slx4 complex
GO:0048257--F:3'-flap endonuclease activity
GO:0017108--F:5'-flap endonuclease activity
GO:0008821--F:crossover junction endodeoxyribonuclease activity
GO:0008047--F:enzyme activator activity
GO:0010792--P:DNA double-strand break processing involved in repair via single-strand annealing
GO:0006260--P:DNA replication
GO:0000724--P:double-strand break repair via homologous recombination
GO:0036297--P:interstrand cross-link repair
GO:0000706--P:meiotic DNA double-strand break processing
GO:1904357--P:negative regulation of telomere maintenance via telomere lengthening
GO:0006289--P:nucleotide-excision repair
GO:1904431--P:positive regulation of t-circle formation
GO:0000712--P:resolution of meiotic recombination intermediates
GO:0072429--P:response to intra-S DNA damage checkpoint signaling
GO:0090656--P:t-circle formation
GO:0061820--P:telomeric D-loop disassembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001225	Ailuropoda melanoleuca	76.31	0.00e+00	1915.00
IUUC-Apl-003261	Anas platyrhynchos	37.97	2.00e-160	560.00
IUUC-Aca-004455	Anolis carolinensis	70.18	2.00e-19	86.70
IUUC-Ame-010993	Astyanax mexicanus	29.13	4.00e-11	61.20
IUUC-Bgr-012247	Blumeria graminis	35.42	6.70e-01	30.00
IUUC-Bta-013472	Bos taurus	60.86	0.00e+00	1489.00
IUUC-Cja-019406	Callithrix jacchus	59.91	0.00e+00	1440.00
IUUC-Cpo-021944	Cavia porcellus	54.47	0.00e+00	1239.00
IUUC-Csa-023941	Chlorocebus sabaeus	57.42	3.00e-179	622.00
IUUC-Cho-024847	Choloepus hoffmanni	64.33	3.00e-139	490.00
IUUC-Cin-025405	Ciona intestinalis	44.23	5.00e-08	52.00
IUUC-Csv-025916	Ciona savignyi	38.98	2.00e-08	52.80
IUUC-Dre-027764	Danio rerio	32.46	4.00e-76	280.00
IUUC-Dno-030083	Dasypus novemcinctus	56.12	0.00e+00	1325.00
IUUC-Dor-031129	Dipodomys ordii	51.50	0.00e+00	989.00
IUUC-Dse-031510	Dothistroma septosporum	36.11	6.30e-02	33.50
IUUC-Ete-032536	Echinops telfairi	46.05	5.00e-84	306.00
IUUC-Eca-033407	Equus caballus	67.37	0.00e+00	1487.00
IUUC-Eeu-034473	Erinaceus europaeus	43.34	4.00e-47	184.00
IUUC-Fca-035730	Felis catus	71.56	0.00e+00	1860.00
IUUC-Fal-036850	Ficedula albicollis	42.31	3.00e-137	484.00
IUUC-Gmo-038677	Gadus morhua	43.75	1.00e-34	141.00
IUUC-Gga-041088	Gallus gallus	41.27	5.00e-144	506.00
IUUC-Gac-041824	Gasterosteus aculeatus	42.05	2.00e-14	72.40
IUUC-Ggo-045642	Gorilla gorilla	58.77	0.00e+00	1009.00
IUUC-Hsa-047035	Homo sapiens	61.25	0.00e+00	1141.00
IUUC-Itr-049010	Ictidomys tridecemlineatus	59.27	0.00e+00	1481.00
IUUC-Lch-050364	Latimeria chalumnae	41.65	1.00e-81	298.00
IUUC-Loc-052423	Lepisosteus oculatus	41.74	2.00e-44	175.00
IUUC-Laf-053910	Loxodonta africana	56.11	0.00e+00	1302.00
IUUC-Mcc-055883	Macaca mulatta	60.59	0.00e+00	1527.00
IUUC-Meu-056224	Macropus eugenii	48.31	4.00e-84	306.00
IUUC-Mga-059880	Meleagris gallopavo	45.34	2.00e-145	510.00
IUUC-Mvi-060510	Microbotryum violaceum	36.36	5.00e-05	43.50
IUUC-Mmr-061715	Microcebus murinus	62.46	0.00e+00	1634.00
IUUC-Mdo-062426	Monodelphis domestica	42.61	0.00e+00	705.00
IUUC-Mmu-063947	Mus musculus	62.50	0.00e+00	763.00
IUUC-Mpu-066184	Mustela putorius furo	76.13	0.00e+00	2110.00
IUUC-Mlu-067533	Myotis lucifugus	65.13	0.00e+00	1605.00
IUUC-Nle-069204	Nomascus leucogenys	60.37	0.00e+00	1524.00
IUUC-Opr-070377	Ochotona princeps	59.02	0.00e+00	815.00
IUUC-Ont-072551	Oreochromis niloticus	31.67	6.00e-72	266.00
IUUC-Oan-073350	Ornithorhynchus anatinus	46.37	2.00e-93	336.00
IUUC-Ocu-074915	Oryctolagus cuniculus	58.91	0.00e+00	846.00
IUUC-Ola-087360	Oryzias latipes	55.91	2.00e-20	92.40
IUUC-Oga-089106	Otolemur garnettii	56.16	0.00e+00	1188.00
IUUC-Oar-089289	Ovis aries	61.58	0.00e+00	1023.00
IUUC-Ptr-091469	Pan troglodytes	61.10	0.00e+00	1124.00
IUUC-Pan-091841	Papio anubis	60.70	0.00e+00	1187.00
IUUC-Psi-093842	Pelodiscus sinensis	46.88	5.00e-129	456.00
IUUC-Pma-094732	Petromyzon marinus	61.54	2.00e-10	58.90
IUUC-Pfo-097299	Poecilia formosa	39.45	4.00e-34	140.00
IUUC-Pab-098271	Pongo abelii	61.02	0.00e+00	1120.00
IUUC-Pca-100721	Procavia capensis	54.14	0.00e+00	868.00
IUUC-Pva-102276	Pteropus vampyrus	69.09	0.00e+00	1802.00
IUUC-Rno-105619	Rattus norvegicus	60.58	0.00e+00	877.00
IUUC-Sha-106722	Sarcophilus harrisii	42.91	0.00e+00	722.00
IUUC-Sar-113673	Sorex araneus	57.39	1.00e-86	315.00
IUUC-Sre-115039	Sporisorium reilianum	31.75	2.00e-04	39.70
IUUC-Ssc-115383	Sus scrofa	61.24	0.00e+00	1370.00
IUUC-Tgu-117243	Taeniopygia guttata	48.87	6.00e-92	330.00
IUUC-Tru-118092	Takifugu rubripes	57.95	3.00e-20	92.00
IUUC-Tsy-119362	Tarsius syrichta	59.10	4.00e-154	539.00
IUUC-Tni-120380	Tetraodon nigroviridis	75.00	5.00e-20	91.30
IUUC-Tbe-127404	Tupaia belangeri	48.42	0.00e+00	631.00
IUUC-Ttr-128317	Tursiops truncatus	65.71	0.00e+00	1536.00
IUUC-Uma-129640	Ustilago maydis	32.26	4.00e-04	38.90
IUUC-Xtr-132533	Xenopus tropicalis	40.92	3.00e-94	340.00
IUUC-Xma-134059	Xiphophorus maculatus	39.38	3.00e-35	144.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence