iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069204

Ensembl Protein ID

ENSNLEP00000011796.1

UniProt Accession

G1REZ6; G1REZ6_NOMLE

Genbank Protein ID

ENSNLEP00000011796

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01048458

Gene Name

SLX4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000009686.1	ENSNLET00000012377.1	ENSNLEP00000011796.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/UBZ	1.00e-10	41.6	294	319

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/UBZ

   S: 2    lvCPvCqkm...vdqtdfeeHlDeCl 24
           ++C++Cqk    +++t++e+H+++Cl
   Q: 294  FFCQICQKNlssMNVTRREQHVNRCL 319
           89***********************8 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MKLSVNETQL GFYLGSLSHL SARPGIDPRS SEDQPESLKT HQMMDESDED FKKLCASFFQ 60
RVKKHGIKEV SGERKTQKAA SDGTQIRSKL KRTKQTATKT KTLQGPAEKK LPSGSQASKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAAACAGT ACTTTTCGTT CAGTTGTGCA AACTCTCCAA GTATCTAACA GAGAAGTAGA 60
GAGGAACCCT AATGAAACTG AGTGTGAATG AGACTCAGCT AGGCTTCTAC TTGGGTTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR018574--Structure-sp_endonuc_su_Slx4

PROSITE

PS50097--BTB

Pfam

PF00651--BTB
PF09494--Slx4

SMART

SM00225--BTB

Gene Ontology

GO:0030054--C:cell junction
GO:0005829--C:cytosol
GO:0070522--C:ERCC4-ERCC1 complex
GO:0048476--C:Holliday junction resolvase complex
GO:0000790--C:nuclear chromatin
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0033557--C:Slx1-Slx4 complex
GO:0048257--F:3'-flap endonuclease activity
GO:0017108--F:5'-flap endonuclease activity
GO:0008821--F:crossover junction endodeoxyribonuclease activity
GO:0008047--F:enzyme activator activity
GO:0010792--P:DNA double-strand break processing involved in repair via single-strand annealing
GO:0006260--P:DNA replication
GO:0000724--P:double-strand break repair via homologous recombination
GO:1904357--P:negative regulation of telomere maintenance via telomere lengthening
GO:0006289--P:nucleotide-excision repair
GO:0072429--P:response to intra-S DNA damage checkpoint signaling
GO:0090656--P:t-circle formation
GO:0061820--P:telomeric D-loop disassembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001225	Ailuropoda melanoleuca	63.79	0.00e+00	1423.00
IUUC-Apl-003261	Anas platyrhynchos	41.07	3.00e-145	510.00
IUUC-Aca-004455	Anolis carolinensis	59.65	3.00e-15	72.80
IUUC-Acl-008026	Aspergillus clavatus	25.51	1.10e-02	35.80
IUUC-Ame-010993	Astyanax mexicanus	35.29	2.00e-10	58.90
IUUC-Bta-013472	Bos taurus	59.51	0.00e+00	1437.00
IUUC-Bdi-014556	Brachypodium distachyon	35.16	4.00e-06	45.40
IUUC-Cel-018663	Caenorhabditis elegans	38.64	4.00e-03	36.60
IUUC-Cja-019406	Callithrix jacchus	84.48	0.00e+00	2461.00
IUUC-Cfa-020129	Canis familiaris	61.24	0.00e+00	1461.00
IUUC-Cpo-021944	Cavia porcellus	60.02	0.00e+00	900.00
IUUC-Csa-023941	Chlorocebus sabaeus	88.77	0.00e+00	1335.00
IUUC-Cho-024847	Choloepus hoffmanni	68.91	2.00e-163	570.00
IUUC-Cin-025405	Ciona intestinalis	42.31	1.00e-06	47.40
IUUC-Csv-025916	Ciona savignyi	38.98	4.00e-08	51.20
IUUC-Dre-027764	Danio rerio	34.86	5.00e-80	293.00
IUUC-Dno-030083	Dasypus novemcinctus	57.33	0.00e+00	1336.00
IUUC-Dor-031129	Dipodomys ordii	52.25	0.00e+00	1043.00
IUUC-Dse-031510	Dothistroma septosporum	38.89	8.90e-02	33.10
IUUC-Ete-032536	Echinops telfairi	46.90	1.00e-120	428.00
IUUC-Eca-033407	Equus caballus	65.16	0.00e+00	1397.00
IUUC-Eeu-034473	Erinaceus europaeus	51.48	1.00e-57	219.00
IUUC-Fca-035730	Felis catus	61.64	0.00e+00	1466.00
IUUC-Fal-036850	Ficedula albicollis	43.29	4.00e-132	466.00
IUUC-Gmo-038677	Gadus morhua	43.35	1.00e-39	158.00
IUUC-Gga-041088	Gallus gallus	37.18	3.00e-126	447.00
IUUC-Gac-041824	Gasterosteus aculeatus	76.32	1.00e-12	66.20
IUUC-Ggo-045642	Gorilla gorilla	93.94	0.00e+00	2412.00
IUUC-Hsa-047035	Homo sapiens	93.96	0.00e+00	2853.00
IUUC-Hvu-047552	Hordeum vulgare	33.33	2.00e-06	45.80
IUUC-Itr-049010	Ictidomys tridecemlineatus	64.16	0.00e+00	1716.00
IUUC-Kpa-049328	Komagataella pastoris	29.23	5.00e-04	39.70
IUUC-Lch-050364	Latimeria chalumnae	41.55	3.00e-80	293.00
IUUC-Loc-052423	Lepisosteus oculatus	37.02	3.00e-50	194.00
IUUC-Lma-053057	Leptosphaeria maculans	29.17	1.10e-01	32.00
IUUC-Laf-053910	Loxodonta africana	57.57	0.00e+00	1372.00
IUUC-Mcc-055883	Macaca mulatta	90.13	0.00e+00	2786.00
IUUC-Meu-056224	Macropus eugenii	51.70	2.00e-86	314.00
IUUC-Mga-059880	Meleagris gallopavo	36.26	1.00e-167	584.00
IUUC-Mvi-060510	Microbotryum violaceum	32.73	2.00e-03	38.50
IUUC-Mmr-061715	Microcebus murinus	69.91	0.00e+00	1965.00
IUUC-Mdo-062426	Monodelphis domestica	42.95	0.00e+00	993.00
IUUC-Mmu-063947	Mus musculus	56.41	0.00e+00	1372.00
IUUC-Mpu-066184	Mustela putorius furo	63.89	0.00e+00	951.00
IUUC-Mlu-067533	Myotis lucifugus	63.38	0.00e+00	1531.00
IUUC-Opr-070377	Ochotona princeps	63.44	0.00e+00	919.00
IUUC-Ont-072551	Oreochromis niloticus	32.10	7.00e-62	233.00
IUUC-Oan-073350	Ornithorhynchus anatinus	48.13	7.00e-96	344.00
IUUC-Ocu-074915	Oryctolagus cuniculus	63.22	0.00e+00	947.00
IUUC-Ola-087360	Oryzias latipes	78.72	2.00e-17	82.40
IUUC-Oga-089106	Otolemur garnettii	62.86	0.00e+00	1406.00
IUUC-Oar-089289	Ovis aries	58.57	0.00e+00	1005.00
IUUC-Ptr-091469	Pan troglodytes	94.29	0.00e+00	2855.00
IUUC-Pan-091841	Papio anubis	90.47	0.00e+00	2191.00
IUUC-Psi-093842	Pelodiscus sinensis	46.35	2.00e-87	318.00
IUUC-Pma-094732	Petromyzon marinus	53.85	2.00e-08	52.00
IUUC-Pfo-097299	Poecilia formosa	37.44	1.00e-30	129.00
IUUC-Pab-098271	Pongo abelii	94.12	0.00e+00	2821.00
IUUC-Pca-100721	Procavia capensis	56.33	0.00e+00	932.00
IUUC-Pva-102276	Pteropus vampyrus	66.27	0.00e+00	1744.00
IUUC-Rno-105619	Rattus norvegicus	57.86	0.00e+00	1487.00
IUUC-Sha-106722	Sarcophilus harrisii	44.33	0.00e+00	1033.00
IUUC-Sar-113673	Sorex araneus	50.27	6.00e-71	263.00
IUUC-Sre-115039	Sporisorium reilianum	33.90	1.00e-04	40.00
IUUC-Ssc-115383	Sus scrofa	57.90	0.00e+00	1274.00
IUUC-Tgu-117243	Taeniopygia guttata	49.00	3.00e-92	332.00
IUUC-Tru-118092	Takifugu rubripes	66.10	1.00e-17	83.20
IUUC-Tsy-119362	Tarsius syrichta	68.79	0.00e+00	750.00
IUUC-Tni-120380	Tetraodon nigroviridis	66.13	9.00e-18	83.60
IUUC-Tbe-127404	Tupaia belangeri	51.49	0.00e+00	748.00
IUUC-Ttr-128317	Tursiops truncatus	65.89	0.00e+00	1612.00
IUUC-Uma-129640	Ustilago maydis	33.96	3.00e-03	35.80
IUUC-Xtr-132533	Xenopus tropicalis	39.80	7.00e-89	322.00
IUUC-Xma-134059	Xiphophorus maculatus	41.31	6.00e-34	140.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence