iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000023135.4	ENSXETT00000050040.4	ENSXETP00000050040.4
ENSXETG00000023135.4	ENSXETT00000065390.1	ENSXETP00000059061.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-63	215.1	171	651

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+r+l+l+     + ++++++++++++ +++++l+ lf+ +++sk+k+v+p++ +++lk++ ++ +
   Q: 171  VGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNysppATAQDVPRNQKEHRNLPFMRELRYLFSLMVSSKRKYVDPSRAVEILKDAFKS-N 258
           6******************************99999999999999999999*******************************99997.9 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
            ++qqD++Ef++ lld le++++                   + +ee++ +k k+++++lF g++    +    +++ + +e f +++l
   Q: 259  DSQQQDVSEFTHKLLDWLEDAFQ------------------IKAEEERDGEKPKNPMVELFYGRFLAVGVH--EGKKFENTEMFGQYPL 327
           **********************2..................22345678999**************77766..456667799******* PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++e+  k+    +++++++lP+vL+++L+Rf+f+++ +++eki++k+efp  L +++
   Q: 328  QVNGFK-----DLHECLEAAMIEGEIES---LHSENSGKS---GQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPPCLYMDR 405
           ******.....9**************96...999998865...589******************************************* PP
   S: 264  fcts..................................................................................... 267
           ++++                                                                                     
   Q: 406  YMHKnreitrlkrdeikrlkehltvlqqrlerylsygsgpkrfpladvlqyalefasskpvctspvedidvsappsgcvatqtvqstie 494
           ****9999999999999999999999999999999999999999999999999999999999999999999999999999999999999 PP
   S: 268  ..................................................................................peekqke 274
                                                                                             ++++ ++
   Q: 495  hqgssaasetqpptqrsvihkpftqsrippdlpmhpaprnitdeelsvlegclhrwrtevetdtrdlqdsigrihrtielmySDKQMNQ 583
           99988888888888888888888888888888888888888888888888888888888888877777777777777777775555556 PP
   S: 275  kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
            + Y+L+av+vH+G+++ GHY+ay+ ++++k W++++D +Vt++++ee ++++      ++aY+l+Y 
   Q: 584  VVPYKLHAVLVHEGQANAGHYWAYIFDHHEKrWMKYNDISVTKSSWEELERDSFggyrnASAYCLMYI 651
           9*************************976667*******************8779************6 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

VSISTRSVAE NMQQHQQTFL NQLREITGIN DLQILQQALK DSNGNLELAV AFLTAKNAKL 60
PQPEEATYYQ TALPNNDRYI SVGSQADTNV IDLTVDDKDD LQRAIALSLE ESNRTFRETG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGACGCACT TTTTGGCGCA TAGATGTCCT AAAATGGACA CCGTACTGGG GAGAGACGGG 60
CGGTGGCGGC CGTAGAAGCA GCAGTCGCAC TGGGAGCCGG GCACTGTCGG CCTGTGGATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0009953--P:dorsal/ventral pattern formation
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001340	Ailuropoda melanoleuca	78.41	0.00e+00	1685.00
IUUC-Apl-004030	Anas platyrhynchos	81.64	0.00e+00	1825.00
IUUC-Aca-004753	Anolis carolinensis	63.30	0.00e+00	994.00
IUUC-Ame-010624	Astyanax mexicanus	71.10	0.00e+00	1108.00
IUUC-Bta-013166	Bos taurus	80.69	0.00e+00	1691.00
IUUC-Cel-018346	Caenorhabditis elegans	28.07	3.00e-28	120.00
IUUC-Cja-019150	Callithrix jacchus	80.10	0.00e+00	1237.00
IUUC-Cfa-020649	Canis familiaris	80.73	0.00e+00	1232.00
IUUC-Cpo-021807	Cavia porcellus	78.74	0.00e+00	1751.00
IUUC-Csa-023388	Chlorocebus sabaeus	80.91	0.00e+00	1258.00
IUUC-Cho-024343	Choloepus hoffmanni	66.35	0.00e+00	832.00
IUUC-Cin-025302	Ciona intestinalis	37.87	9.00e-97	347.00
IUUC-Dre-028016	Danio rerio	73.84	0.00e+00	1165.00
IUUC-Dno-029495	Dasypus novemcinctus	77.61	0.00e+00	1232.00
IUUC-Dor-030948	Dipodomys ordii	67.18	0.00e+00	1180.00
IUUC-Fca-035876	Felis catus	81.21	0.00e+00	1716.00
IUUC-Fal-036762	Ficedula albicollis	82.64	0.00e+00	1103.00
IUUC-Fox-037752	Fusarium oxysporum	24.70	2.00e-16	81.60
IUUC-Gmo-039490	Gadus morhua	72.05	0.00e+00	1552.00
IUUC-Gga-040817	Gallus gallus	84.05	0.00e+00	1327.00
IUUC-Gac-042473	Gasterosteus aculeatus	72.14	0.00e+00	1575.00
IUUC-Ggo-044939	Gorilla gorilla	76.99	0.00e+00	1647.00
IUUC-Hsa-046204	Homo sapiens	81.07	0.00e+00	1714.00
IUUC-Kpa-049349	Komagataella pastoris	29.17	3.00e-10	61.20
IUUC-Lch-049572	Latimeria chalumnae	80.42	0.00e+00	1253.00
IUUC-Loc-052070	Lepisosteus oculatus	78.55	0.00e+00	1212.00
IUUC-Laf-054426	Loxodonta africana	80.14	0.00e+00	1592.00
IUUC-Mcc-055858	Macaca mulatta	81.14	0.00e+00	1262.00
IUUC-Meu-056719	Macropus eugenii	66.46	2.00e-169	589.00
IUUC-Mga-059808	Meleagris gallopavo	84.18	0.00e+00	1824.00
IUUC-Mmr-060987	Microcebus murinus	81.49	0.00e+00	1223.00
IUUC-Mmu-064245	Mus musculus	79.25	0.00e+00	1705.00
IUUC-Mpu-066304	Mustela putorius furo	80.39	0.00e+00	1239.00
IUUC-Mlu-067139	Myotis lucifugus	80.15	0.00e+00	1742.00
IUUC-Nfi-068458	Neosartorya fischeri	24.30	2.00e-13	71.60
IUUC-Nle-069075	Nomascus leucogenys	80.88	0.00e+00	1706.00
IUUC-Ont-072150	Oreochromis niloticus	74.57	0.00e+00	1193.00
IUUC-Oan-073054	Ornithorhynchus anatinus	76.31	0.00e+00	1628.00
IUUC-Ocu-074102	Oryctolagus cuniculus	78.70	0.00e+00	1230.00
IUUC-Ola-086529	Oryzias latipes	70.37	0.00e+00	1519.00
IUUC-Oga-088939	Otolemur garnettii	80.84	0.00e+00	1703.00
IUUC-Oar-090266	Ovis aries	81.14	0.00e+00	1221.00
IUUC-Ptr-090546	Pan troglodytes	80.98	0.00e+00	1712.00
IUUC-Pan-092311	Papio anubis	81.01	0.00e+00	1261.00
IUUC-Psi-093459	Pelodiscus sinensis	89.71	0.00e+00	1165.00
IUUC-Pfo-096726	Poecilia formosa	72.50	0.00e+00	1160.00
IUUC-Pab-097608	Pongo abelii	78.53	0.00e+00	1688.00
IUUC-Pca-100718	Procavia capensis	75.97	0.00e+00	1055.00
IUUC-Pva-103150	Pteropus vampyrus	75.42	0.00e+00	1268.00
IUUC-Pte-104300	Pyrenophora teres	23.24	2.00e-13	72.00
IUUC-Rno-105727	Rattus norvegicus	79.35	0.00e+00	1680.00
IUUC-Sha-107051	Sarcophilus harrisii	83.80	0.00e+00	1789.00
IUUC-Sar-113097	Sorex araneus	73.86	0.00e+00	1584.00
IUUC-Ssc-115877	Sus scrofa	78.61	0.00e+00	1688.00
IUUC-Tgu-117473	Taeniopygia guttata	77.71	0.00e+00	1687.00
IUUC-Tru-118135	Takifugu rubripes	65.50	0.00e+00	1394.00
IUUC-Tsy-119471	Tarsius syrichta	74.38	0.00e+00	1506.00
IUUC-Tni-120139	Tetraodon nigroviridis	68.04	0.00e+00	1322.00
IUUC-Tbe-127549	Tupaia belangeri	74.86	0.00e+00	1600.00
IUUC-Ttr-128896	Tursiops truncatus	74.61	0.00e+00	1583.00
IUUC-Uma-129338	Ustilago maydis	25.00	4.00e-13	70.90
IUUC-Vpa-130500	Vicugna pacos	80.08	0.00e+00	1155.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence