iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000011774.3	ENSOCUT00000011773.2	ENSOCUP00000010119.2
ENSOCUG00000011774.3	ENSOCUT00000033462.1	ENSOCUP00000026509.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	9.60e-06	25.8	202	248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 100  aglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
           ++ +++lp e++++i+++l+++el+r+++v+ +w++la++ +lwk++
   Q: 202  STGITHLPPEVMLSIFSYLNPQELCRCSQVSTKWSQLAKTGSLWKHL 248
           556789*********************************9****987 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

VMPFMEEINV KFAPFSQMHL LSLSYCDVLS KTNFSNNNDF RALLQSLYAT FKEFKMHEQI 60
ENEYIIGLLQ QRSQTIYNVH SDNKLSEMLS LFEKGLKNVK NEYEQLNYAK QLKERLEAFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAATGCCTT TTATGGAAGG TACTTAGTTA ATTTTTTTAT GTGTAGTGGA ATTGTTTTGA 60
CTTAGGAGTT TGCACCTCTT CTTTTCTGTT ACTCTTTAAT CAGAATATAG TTCCTGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005506--F:iron ion binding
GO:0055072--P:iron ion homeostasis
GO:1903364--P:positive regulation of cellular protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002319	Ailuropoda melanoleuca	94.44	0.00e+00	1179.00
IUUC-Apl-003755	Anas platyrhynchos	79.82	0.00e+00	998.00
IUUC-Aca-004798	Anolis carolinensis	74.89	0.00e+00	1004.00
IUUC-Ame-011091	Astyanax mexicanus	58.03	0.00e+00	729.00
IUUC-Bta-013204	Bos taurus	92.04	0.00e+00	1181.00
IUUC-Cja-019594	Callithrix jacchus	93.98	0.00e+00	1036.00
IUUC-Cfa-020965	Canis familiaris	92.33	0.00e+00	1189.00
IUUC-Cpo-021308	Cavia porcellus	90.30	0.00e+00	1200.00
IUUC-Csa-023865	Chlorocebus sabaeus	92.62	0.00e+00	1258.00
IUUC-Cho-024778	Choloepus hoffmanni	83.24	5.00e-165	574.00
IUUC-Dre-027628	Danio rerio	52.12	3.00e-165	575.00
IUUC-Dno-029899	Dasypus novemcinctus	90.96	0.00e+00	1243.00
IUUC-Dor-031105	Dipodomys ordii	78.93	0.00e+00	1034.00
IUUC-Ete-032314	Echinops telfairi	86.27	0.00e+00	1078.00
IUUC-Eca-033797	Equus caballus	93.40	0.00e+00	1131.00
IUUC-Eeu-034811	Erinaceus europaeus	84.68	0.00e+00	901.00
IUUC-Fca-036516	Felis catus	93.82	0.00e+00	1164.00
IUUC-Fal-036824	Ficedula albicollis	78.65	0.00e+00	942.00
IUUC-Gga-040271	Gallus gallus	78.61	0.00e+00	1028.00
IUUC-Gac-041399	Gasterosteus aculeatus	58.80	0.00e+00	753.00
IUUC-Ggo-044415	Gorilla gorilla	92.76	0.00e+00	1258.00
IUUC-Hsa-047001	Homo sapiens	92.76	0.00e+00	1287.00
IUUC-Itr-048356	Ictidomys tridecemlineatus	93.58	0.00e+00	1058.00
IUUC-Lch-049897	Latimeria chalumnae	63.90	0.00e+00	790.00
IUUC-Loc-052162	Lepisosteus oculatus	63.64	0.00e+00	822.00
IUUC-Laf-054031	Loxodonta africana	91.90	0.00e+00	1215.00
IUUC-Mcc-054680	Macaca mulatta	92.62	0.00e+00	1258.00
IUUC-Meu-056199	Macropus eugenii	84.14	4.00e-105	375.00
IUUC-Mga-059675	Meleagris gallopavo	79.91	0.00e+00	1014.00
IUUC-Mmr-061694	Microcebus murinus	92.47	0.00e+00	1261.00
IUUC-Mdo-062900	Monodelphis domestica	87.26	0.00e+00	1178.00
IUUC-Mmu-063178	Mus musculus	90.45	0.00e+00	1230.00
IUUC-Mpu-066584	Mustela putorius furo	91.90	0.00e+00	1196.00
IUUC-Mlu-067859	Myotis lucifugus	93.36	0.00e+00	1181.00
IUUC-Nle-069172	Nomascus leucogenys	93.34	0.00e+00	1237.00
IUUC-Opr-070992	Ochotona princeps	93.53	0.00e+00	1055.00
IUUC-Ont-072577	Oreochromis niloticus	59.47	0.00e+00	756.00
IUUC-Oan-072870	Ornithorhynchus anatinus	83.63	0.00e+00	899.00
IUUC-Ola-087146	Oryzias latipes	58.45	0.00e+00	741.00
IUUC-Oga-088307	Otolemur garnettii	93.54	0.00e+00	1225.00
IUUC-Oar-090192	Ovis aries	92.76	0.00e+00	1184.00
IUUC-Ptr-091049	Pan troglodytes	93.05	0.00e+00	1263.00
IUUC-Pan-091995	Papio anubis	92.76	0.00e+00	1260.00
IUUC-Psi-093154	Pelodiscus sinensis	79.91	0.00e+00	992.00
IUUC-Pma-094334	Petromyzon marinus	47.53	2.00e-139	489.00
IUUC-Pfo-096154	Poecilia formosa	58.08	0.00e+00	734.00
IUUC-Pab-098264	Pongo abelii	95.32	0.00e+00	1246.00
IUUC-Pca-100884	Procavia capensis	70.04	0.00e+00	884.00
IUUC-Pva-102114	Pteropus vampyrus	91.18	0.00e+00	1228.00
IUUC-Rno-105392	Rattus norvegicus	91.17	0.00e+00	1234.00
IUUC-Sha-106508	Sarcophilus harrisii	89.31	0.00e+00	1154.00
IUUC-Sar-113107	Sorex araneus	89.94	0.00e+00	838.00
IUUC-Ssc-115489	Sus scrofa	92.33	0.00e+00	1187.00
IUUC-Tgu-116734	Taeniopygia guttata	78.09	0.00e+00	994.00
IUUC-Tru-117632	Takifugu rubripes	58.82	0.00e+00	743.00
IUUC-Tsy-119400	Tarsius syrichta	93.67	0.00e+00	1194.00
IUUC-Tni-120602	Tetraodon nigroviridis	58.09	0.00e+00	758.00
IUUC-Tbe-127833	Tupaia belangeri	91.57	0.00e+00	642.00
IUUC-Ttr-129289	Tursiops truncatus	91.95	0.00e+00	733.00
IUUC-Vpa-130253	Vicugna pacos	96.13	0.00e+00	644.00
IUUC-Vvi-131468	Vitis vinifera	32.39	2.00e-05	43.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence