iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-034062

Ensembl Protein ID

ENSECAP00000007251.1

UniProt Accession

F6Y6E7; F6Y6E7_HORSE

Protein Name

Uncharacterized protein

Gene Name

NCF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000008957.1	ENSECAT00000009512.1	ENSECAP00000007251.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.30e-11	42.5	175	228
ULD/UDP/UFD/PB1	4.10e-22	78.3	237	328

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            ++l+d++++++ eL++k+Gdv++++     +++Wl+g  + +g  G+fP  Fv+ l+
   Q: 175  AEALFDFTGNSKLELNFKAGDVIFLL--SRINKDWLEG--TVRGATGIFPLSFVKILK 228
           689***********************..999*******..8*************9776 PP

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirs......faldlekpgkfedLlkavrtltelknsevalkYeDedGDlvtlksDedldkavslla...skksll..r 78
           t++++++y+++++s      +++dl+++++f+dLl+++r+  e++++++al+Y+D+dGDlv+l sDed++ +v++++   ++k+l+  +
   Q: 237  TNWLRCYYYEDTIStikdiaVEEDLSSTPLFKDLLELMRR--EFQREDIALNYRDADGDLVRLLSDEDVALMVRQARglpTQKRLFpwK 323
           589**********9**************************..********************************************999 PP
   S: 79   lliqk 83
           l++++
   Q: 324  LHVTQ 328
           99987 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAVAQQLRAE SDFEQLPDDI AISANIADIE EKRGFTSHFV FVIEVKTKGG SKYLIYRRYR 60
QFHALQSKLE ERFGPENKSN AFTCSLPTLP AKVYVGVKKE IAESRIPALN AYMKSLLSLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGACCCTTT GACACCCACT CTCCTGGACC ACTGACGGCC ATGGCCGTGG CCCAGCAGCT 60
GCGGGCTGAG AGGTGAGTGC GAGGCGCCGC CCTCCCTGGG CCTCCTCACT GTCCCCTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000919--NCF_P40
IPR000270--PB1_dom
IPR001683--Phox
IPR001452--SH3_domain

PROSITE

PS51745--PB1
PS50195--PX
PS50002--SH3

Pfam

PF00564--PB1
PF00787--PX
PF00018--SH3_1

PRINTS

PR00497--P40PHOX

SMART

SM00666--PB1
SM00312--PX
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0010008--C:endosome membrane
GO:0043020--C:NADPH oxidase complex
GO:0005802--C:trans-Golgi network
GO:0005086--F:ARF guanyl-nucleotide exchange factor activity
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0016176--F:superoxide-generating NADPH oxidase activator activity
GO:0016192--P:vesicle-mediated transport

KEGG

ecb:100069566

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001675	Ailuropoda melanoleuca	89.38	0.00e+00	632.00
IUUC-Apl-003431	Anas platyrhynchos	66.37	8.00e-136	476.00
IUUC-Aca-005176	Anolis carolinensis	70.83	5.00e-141	493.00
IUUC-Ame-011492	Astyanax mexicanus	57.75	1.00e-115	409.00
IUUC-Bta-013434	Bos taurus	89.68	7.00e-169	586.00
IUUC-Cja-019788	Callithrix jacchus	89.38	0.00e+00	632.00
IUUC-Cfa-021039	Canis familiaris	90.56	2.00e-177	614.00
IUUC-Cpo-021848	Cavia porcellus	86.73	9.00e-173	598.00
IUUC-Csa-023733	Chlorocebus sabaeus	89.80	2.00e-159	554.00
IUUC-Dre-027732	Danio rerio	55.06	3.00e-99	354.00
IUUC-Dno-029154	Dasypus novemcinctus	77.78	9.00e-153	532.00
IUUC-Eeu-035129	Erinaceus europaeus	84.56	4.00e-71	261.00
IUUC-Fca-036402	Felis catus	91.45	0.00e+00	644.00
IUUC-Fal-037105	Ficedula albicollis	66.67	6.00e-136	476.00
IUUC-Gmo-039144	Gadus morhua	47.95	7.00e-38	149.00
IUUC-Gga-040526	Gallus gallus	66.08	3.00e-134	471.00
IUUC-Ggo-044667	Gorilla gorilla	91.09	2.00e-139	488.00
IUUC-Hsa-045779	Homo sapiens	91.74	0.00e+00	648.00
IUUC-Itr-048385	Ictidomys tridecemlineatus	71.35	2.00e-133	468.00
IUUC-Lch-050264	Latimeria chalumnae	52.41	7.00e-112	396.00
IUUC-Loc-051887	Lepisosteus oculatus	53.67	2.00e-105	375.00
IUUC-Laf-054411	Loxodonta africana	81.82	1.00e-154	538.00
IUUC-Mcc-055835	Macaca mulatta	89.94	4.00e-179	620.00
IUUC-Meu-056875	Macropus eugenii	80.30	8.00e-93	332.00
IUUC-Mga-059737	Meleagris gallopavo	65.78	2.00e-133	468.00
IUUC-Mmr-061065	Microcebus murinus	87.97	4.00e-126	443.00
IUUC-Mdo-062598	Monodelphis domestica	80.59	4.00e-159	553.00
IUUC-Mmu-063643	Mus musculus	86.14	1.00e-176	612.00
IUUC-Mpu-066142	Mustela putorius furo	89.09	0.00e+00	637.00
IUUC-Mlu-067898	Myotis lucifugus	87.78	5.00e-45	171.00
IUUC-Nle-069935	Nomascus leucogenys	78.01	1.00e-148	518.00
IUUC-Opr-070204	Ochotona princeps	83.85	2.00e-132	465.00
IUUC-Ont-072261	Oreochromis niloticus	56.00	3.00e-107	381.00
IUUC-Oan-072846	Ornithorhynchus anatinus	78.34	4.00e-73	266.00
IUUC-Ocu-074683	Oryctolagus cuniculus	88.53	0.00e+00	626.00
IUUC-Opu-083873	Oryza punctata	36.11	9.00e+00	25.80
IUUC-Ola-086700	Oryzias latipes	55.30	1.00e-97	349.00
IUUC-Oga-087992	Otolemur garnettii	89.79	2.00e-178	617.00
IUUC-Oar-089828	Ovis aries	88.86	2.00e-166	578.00
IUUC-Pan-092264	Papio anubis	89.38	0.00e+00	635.00
IUUC-Psi-093800	Pelodiscus sinensis	68.73	1.00e-135	475.00
IUUC-Pfo-096677	Poecilia formosa	52.25	5.00e-87	314.00
IUUC-Pab-097920	Pongo abelii	90.86	0.00e+00	641.00
IUUC-Pca-100312	Procavia capensis	72.69	1.00e-98	353.00
IUUC-Pva-102113	Pteropus vampyrus	88.42	5.00e-137	480.00
IUUC-Rno-105777	Rattus norvegicus	86.73	5.00e-178	616.00
IUUC-Sha-106666	Sarcophilus harrisii	79.71	6.00e-165	573.00
IUUC-Ssc-116056	Sus scrofa	87.32	2.00e-180	624.00
IUUC-Tgu-116797	Taeniopygia guttata	67.55	4.00e-139	487.00
IUUC-Tru-117860	Takifugu rubripes	53.60	3.00e-98	351.00
IUUC-Tsy-119537	Tarsius syrichta	89.70	9.00e-86	310.00
IUUC-Tni-119946	Tetraodon nigroviridis	55.40	3.00e-100	358.00
IUUC-Tbe-127274	Tupaia belangeri	74.61	2.00e-108	384.00
IUUC-Ttr-129026	Tursiops truncatus	89.95	6.00e-111	393.00
IUUC-Xtr-131910	Xenopus tropicalis	53.39	2.00e-109	388.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence