iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091523

UUCD1 version

UUC-PaT-00178

Ensembl Protein ID

ENSPTRP00000006792.4

UniProt Accession

H2Q481; H2Q481_PANTR

Genbank Protein ID

JAA14669.1; JAA27402.1; JAA38561.1

Protein Name

Lysine (K)-specific demethylase 2A

Genbank Nucleotide ID

AACZ03082716; GABD01005698; GABE01006178

Gene Name

KDM2A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000003945.4	ENSPTRT00000007365.4	ENSPTRP00000006792.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.00e-10	40.1	619	677

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedek......slveCekCrewfHpaClkls....veeelpnsekwiCpkCrs 53
            C +Cge +++e+      +l+eC++C+e++Hp+Cl++      +eelpn+  w+CpkC +
   Q: 619  TCSLCGEVDQNEEtqdfekKLMECCICNEIVHPGCLQMDgeglLNEELPNC--WECPKCYQ 677
           7*********995555666***********************99*******..******76 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MEPEEERIRY SQRLRGTMRR RYEDDGISDD EIEGKRTFDL EEKLHTNKYN ANFVTFMEGK 60
DFNVEYIQRG GLRDPLIFKN SDGLGIKMPD PDFTVNDVKM CVGSRRMVDV MDVNTQKGIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTCTGACG GGTTCAAAAT GGCGGCGGCT GCTTCAGCGG CTCCTCCTGT GTGAGGGAAA 60
CAACACCCCT CCCCGGCAGC GGCGGCGGCG GCGGCGGCTC TCGGAGCACC TTCCCAGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR019786--Zinc_finger_PHD-type_CS
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF02373--JmjC
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0008168--F:methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0070544--P:histone H3-K36 demethylation

KEGG

ptr:107967129; ptr:451362

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002052	Ailuropoda melanoleuca	88.68	0.00e+00	1149.00
IUUC-Apl-003192	Anas platyrhynchos	77.56	0.00e+00	1052.00
IUUC-Aca-004576	Anolis carolinensis	84.02	0.00e+00	1914.00
IUUC-Ago-007912	Ashbya gossypii	37.24	2.00e-52	199.00
IUUC-Ame-011753	Astyanax mexicanus	57.30	0.00e+00	781.00
IUUC-Bta-012730	Bos taurus	87.44	0.00e+00	1871.00
IUUC-Cja-019030	Callithrix jacchus	98.80	0.00e+00	2141.00
IUUC-Cfa-020644	Canis familiaris	99.48	0.00e+00	2175.00
IUUC-Cpo-022055	Cavia porcellus	97.85	0.00e+00	2120.00
IUUC-Csa-023379	Chlorocebus sabaeus	99.74	0.00e+00	2112.00
IUUC-Cho-024541	Choloepus hoffmanni	77.48	0.00e+00	1431.00
IUUC-Cin-025140	Ciona intestinalis	61.09	2.00e-107	383.00
IUUC-Csv-025861	Ciona savignyi	45.14	2.00e-134	473.00
IUUC-Cne-026797	Cryptococcus neoformans	38.51	5.00e-59	222.00
IUUC-Dno-029268	Dasypus novemcinctus	98.71	0.00e+00	2122.00
IUUC-Dor-031142	Dipodomys ordii	98.91	0.00e+00	1025.00
IUUC-Dme-032039	Drosophila melanogaster	60.36	1.00e-124	441.00
IUUC-Ete-032467	Echinops telfairi	89.15	0.00e+00	1898.00
IUUC-Eca-033526	Equus caballus	98.97	0.00e+00	2137.00
IUUC-Eeu-035273	Erinaceus europaeus	84.05	0.00e+00	1425.00
IUUC-Fca-035532	Felis catus	99.48	0.00e+00	2106.00
IUUC-Fal-037140	Ficedula albicollis	86.87	0.00e+00	1929.00
IUUC-Gmo-038932	Gadus morhua	58.95	0.00e+00	793.00
IUUC-Gga-040418	Gallus gallus	83.26	0.00e+00	1097.00
IUUC-Gac-041674	Gasterosteus aculeatus	55.98	0.00e+00	1196.00
IUUC-Ggo-045330	Gorilla gorilla	94.33	0.00e+00	802.00
IUUC-Hsa-046180	Homo sapiens	100.00	0.00e+00	2189.00
IUUC-Itr-048198	Ictidomys tridecemlineatus	98.98	0.00e+00	1424.00
IUUC-Lch-049730	Latimeria chalumnae	60.19	0.00e+00	983.00
IUUC-Laf-053939	Loxodonta africana	98.43	0.00e+00	2139.00
IUUC-Mcc-054600	Macaca mulatta	99.57	0.00e+00	2139.00
IUUC-Meu-056314	Macropus eugenii	92.41	0.00e+00	1198.00
IUUC-Mga-059549	Meleagris gallopavo	78.70	0.00e+00	1132.00
IUUC-Mmr-060865	Microcebus murinus	99.57	0.00e+00	2156.00
IUUC-Mdo-062567	Monodelphis domestica	95.44	0.00e+00	2083.00
IUUC-Mmu-063782	Mus musculus	96.90	0.00e+00	2131.00
IUUC-Mpu-066055	Mustela putorius furo	99.23	0.00e+00	2178.00
IUUC-Mlu-067228	Myotis lucifugus	90.70	0.00e+00	1144.00
IUUC-Nle-069668	Nomascus leucogenys	99.74	0.00e+00	2142.00
IUUC-Opr-070225	Ochotona princeps	96.28	0.00e+00	2079.00
IUUC-Ont-071349	Oreochromis niloticus	52.67	0.00e+00	1086.00
IUUC-Oan-073668	Ornithorhynchus anatinus	79.19	0.00e+00	670.00
IUUC-Ocu-074710	Oryctolagus cuniculus	98.71	0.00e+00	2102.00
IUUC-Ola-087410	Oryzias latipes	57.81	0.00e+00	770.00
IUUC-Oga-088644	Otolemur garnettii	99.27	0.00e+00	2053.00
IUUC-Oar-089193	Ovis aries	98.09	0.00e+00	2078.00
IUUC-Pan-092415	Papio anubis	99.74	0.00e+00	2148.00
IUUC-Psi-093607	Pelodiscus sinensis	90.94	0.00e+00	1051.00
IUUC-Ppa-095609	Physcomitrella patens	37.58	4.00e-58	218.00
IUUC-Pfo-096695	Poecilia formosa	51.11	0.00e+00	1087.00
IUUC-Pab-098580	Pongo abelii	100.00	0.00e+00	1244.00
IUUC-Pca-100670	Procavia capensis	94.43	0.00e+00	1533.00
IUUC-Pva-102416	Pteropus vampyrus	91.83	0.00e+00	1924.00
IUUC-Pgr-103554	Puccinia graminis	44.67	3.00e-74	272.00
IUUC-Rno-105814	Rattus norvegicus	97.33	0.00e+00	2152.00
IUUC-Sce-106445	Saccharomyces cerevisiae	43.46	5.00e-50	191.00
IUUC-Sha-106693	Sarcophilus harrisii	95.00	0.00e+00	1962.00
IUUC-Sar-113568	Sorex araneus	95.38	0.00e+00	2031.00
IUUC-Sre-115112	Sporisorium reilianum	40.94	1.00e-59	224.00
IUUC-Ssc-116337	Sus scrofa	98.12	0.00e+00	1569.00
IUUC-Tgu-117298	Taeniopygia guttata	87.37	0.00e+00	1927.00
IUUC-Tru-118423	Takifugu rubripes	53.26	0.00e+00	1129.00
IUUC-Tsy-119293	Tarsius syrichta	97.93	0.00e+00	2051.00
IUUC-Tni-120020	Tetraodon nigroviridis	56.95	0.00e+00	764.00
IUUC-Tbe-127450	Tupaia belangeri	86.39	0.00e+00	1766.00
IUUC-Ttr-128837	Tursiops truncatus	89.47	0.00e+00	924.00
IUUC-Uma-129458	Ustilago maydis	40.31	3.00e-60	226.00
IUUC-Vpa-130655	Vicugna pacos	93.45	0.00e+00	1498.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence