iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000004108.1	ENSORLT00000005142.1	ENSORLP00000005141.1
ENSORLG00000004108.1	ENSORLT00000005143.1	ENSORLP00000005142.1
ENSORLG00000004108.1	ENSORLT00000005145.1	ENSORLP00000005144.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-114	382.8	597	926

Active Site

Position(s)	Description	Evidence
897	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           ++lk+ + v+f gEeg+++ Gv re+++ ls+e+ npd+ lf++s+ d +t+qpn++s + np+hl++F+f+G++lg+al++++l+++ 
   Q: 597  EKLKQGIAVRFHGEEGMGQ-GVVREWFDILSSEIINPDYALFTQSA-DGTTFQPNSNSSV-NPDHLNYFQFAGQILGLALYHRQLVNIY 682
           78999**************.**********************6666.67788*******9.89************************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           +++sfyk++lg ++s++d++++dpe++k+l++i++n   di++lgl+ltfsv+++++g ++e+ Lk gG ++ Vt+eNk eYv+lv+e+
   Q: 683  FTRSFYKHILGIPVSYQDVSSIDPEYAKNLQWILDN---DISDLGLELTFSVETDVFGAMEEVPLKAGGTTTLVTQENKAEYVQLVTEL 768
           **********************************99...************************************************** PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           r+++ i+ q++af +Gf++ ip++l++lF+e elell++G++eidved+ ++t+y++gy++++p++qwFwev++++++eer  +LqFvT
   Q: 769  RMTRAIQPQINAFLRGFHTFIPPSLIQLFDEYELELLLSGMPEIDVEDWFRNTEYTSGYSDQEPVVQWFWEVVKGLTQEERILLLQFVT 857
           ***************************************************************************************** PP
   S: 270  gssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kg 332
           gssr+P+gGfa l+     ++f+i     +++ lP+++TC+n+LkLPeY+s  +l+++Ll+A + +  g
   Q: 858  GSSRVPHGGFAFLMggsgLQKFTIAAmPYTPNLLPTASTCINMLKLPEYPSLVVLQDRLLVALHCGsYG 926
           ******************8888888878899********************************986555 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MERAMEQLNV QLNRLTRSLR RARTVELPED NETAVYTLMP MVMADQHRSV SELLLNSRFD 60
VNYAFGRVKR SLLHIAANCG SVECLVLLLK KGANPNYQDI SGCTPLHLAA RNGQKKCMSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCAGACAGA TAGGGCGTCC ATGGGCTACG CCCGCGGAAG TTCCAGGCTC CACCGGGGAC 60
CAACGACGCC GCCGCGCAGC GCTCCCCTAT GATGGAACGG GCGATGGAGC AGCTCAACGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000569--HECT_dom

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50237--HECT

Pfam

PF12796--Ank_2
PF00632--HECT

PRINTS

PR01415--ANKYRIN

SMART

SM00248--ANK
SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	40.18	2.00e-83	305.00
IUUC-Aml-001490	Ailuropoda melanoleuca	81.70	0.00e+00	1584.00
IUUC-Atr-002582	Amborella trichopoda	43.86	2.00e-100	362.00
IUUC-Apl-003400	Anas platyrhynchos	77.90	0.00e+00	1027.00
IUUC-Aca-005375	Anolis carolinensis	80.72	0.00e+00	1582.00
IUUC-Aly-006157	Arabidopsis lyrata	44.87	2.00e-101	365.00
IUUC-Ath-007160	Arabidopsis thaliana	42.53	1.00e-95	346.00
IUUC-Afu-009022	Aspergillus fumigatus	42.89	4.00e-97	351.00
IUUC-Ani-009412	Aspergillus nidulans	42.56	4.00e-98	355.00
IUUC-Ate-010253	Aspergillus terreus	42.79	3.00e-97	351.00
IUUC-Ame-011847	Astyanax mexicanus	87.46	0.00e+00	1703.00
IUUC-Bta-012831	Bos taurus	81.72	0.00e+00	1552.00
IUUC-Bdi-014884	Brachypodium distachyon	43.28	1.00e-98	356.00
IUUC-Bol-016533	Brassica oleracea	53.07	3.00e-79	288.00
IUUC-Bra-016726	Brassica rapa	44.87	1.00e-101	366.00
IUUC-Cja-019160	Callithrix jacchus	82.09	0.00e+00	1597.00
IUUC-Cfa-020346	Canis familiaris	81.86	0.00e+00	1595.00
IUUC-Cpo-021766	Cavia porcellus	82.07	0.00e+00	1594.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	42.89	2.00e-96	345.00
IUUC-Csa-023768	Chlorocebus sabaeus	81.96	0.00e+00	1598.00
IUUC-Cho-024688	Choloepus hoffmanni	73.47	0.00e+00	942.00
IUUC-Cin-025417	Ciona intestinalis	46.72	3.00e-140	492.00
IUUC-Csv-025993	Ciona savignyi	43.52	0.00e+00	767.00
IUUC-Cne-027095	Cryptococcus neoformans	39.13	2.00e-79	292.00
IUUC-Cme-027267	Cyanidioschyzon merolae	40.74	1.00e-83	305.00
IUUC-Dre-027819	Danio rerio	85.90	0.00e+00	1669.00
IUUC-Dno-029027	Dasypus novemcinctus	81.34	0.00e+00	1579.00
IUUC-Dor-030327	Dipodomys ordii	75.27	0.00e+00	1385.00
IUUC-Ete-032966	Echinops telfairi	75.87	0.00e+00	1459.00
IUUC-Eca-034339	Equus caballus	81.96	0.00e+00	1591.00
IUUC-Eeu-034544	Erinaceus europaeus	72.56	6.00e-133	468.00
IUUC-Fca-035617	Felis catus	77.16	0.00e+00	1076.00
IUUC-Fal-036687	Ficedula albicollis	82.82	0.00e+00	1626.00
IUUC-Gmo-039508	Gadus morhua	89.07	0.00e+00	834.00
IUUC-Gga-040845	Gallus gallus	82.51	0.00e+00	1625.00
IUUC-Gac-041894	Gasterosteus aculeatus	86.77	0.00e+00	1636.00
IUUC-Gma-044216	Glycine max	44.55	4.00e-102	368.00
IUUC-Ggo-044465	Gorilla gorilla	78.65	0.00e+00	1523.00
IUUC-Hsa-045731	Homo sapiens	82.07	0.00e+00	1599.00
IUUC-Hvu-047697	Hordeum vulgare	43.28	1.00e-97	353.00
IUUC-Itr-048716	Ictidomys tridecemlineatus	82.33	0.00e+00	1600.00
IUUC-Lch-050436	Latimeria chalumnae	83.32	0.00e+00	1630.00
IUUC-Lpe-051550	Leersia perrieri	43.51	3.00e-99	358.00
IUUC-Loc-052287	Lepisosteus oculatus	85.37	0.00e+00	1691.00
IUUC-Lma-053159	Leptosphaeria maculans	39.16	1.00e-92	336.00
IUUC-Laf-053846	Loxodonta africana	82.19	0.00e+00	1599.00
IUUC-Mcc-055845	Macaca mulatta	81.96	0.00e+00	1598.00
IUUC-Meu-056060	Macropus eugenii	81.53	0.00e+00	633.00
IUUC-Mtr-057633	Medicago truncatula	42.98	5.00e-103	371.00
IUUC-Mga-059935	Meleagris gallopavo	81.38	0.00e+00	1582.00
IUUC-Mmr-060960	Microcebus murinus	82.38	0.00e+00	1602.00
IUUC-Mdo-061851	Monodelphis domestica	82.86	0.00e+00	1617.00
IUUC-Mmu-063657	Mus musculus	81.79	0.00e+00	1598.00
IUUC-Mac-065229	Musa acuminata	43.41	6.00e-100	360.00
IUUC-Mpu-066161	Mustela putorius furo	87.94	0.00e+00	743.00
IUUC-Mlu-067354	Myotis lucifugus	80.75	0.00e+00	1521.00
IUUC-Nfi-068278	Neosartorya fischeri	42.89	3.00e-97	352.00
IUUC-Nle-069112	Nomascus leucogenys	82.07	0.00e+00	1599.00
IUUC-Opr-070686	Ochotona princeps	78.82	0.00e+00	726.00
IUUC-Ont-072398	Oreochromis niloticus	86.51	0.00e+00	1639.00
IUUC-Oan-073194	Ornithorhynchus anatinus	81.62	0.00e+00	1543.00
IUUC-Ocu-074397	Oryctolagus cuniculus	74.60	0.00e+00	1403.00
IUUC-Oba-075757	Oryza barthii	43.28	2.00e-98	355.00
IUUC-Obr-076553	Oryza brachyantha	43.74	1.00e-98	356.00
IUUC-Ogl-077520	Oryza glaberrima	43.28	3.00e-98	355.00
IUUC-Ogu-078278	Oryza glumaepatula	43.28	3.00e-98	355.00
IUUC-Oin-079767	Oryza indica	43.28	3.00e-98	355.00
IUUC-Olo-080380	Oryza longistaminata	43.12	8.00e-97	350.00
IUUC-Ome-081925	Oryza meridionalis	43.12	6.00e-97	350.00
IUUC-Oni-082619	Oryza nivara	43.28	3.00e-98	355.00
IUUC-Opu-083684	Oryza punctata	43.12	7.00e-97	350.00
IUUC-Oru-084501	Oryza rufipogon	43.28	3.00e-98	355.00
IUUC-Osa-086251	Oryza sativa	43.28	1.00e-98	353.00
IUUC-Olu-087813	Ostreococcus lucimarinus	39.57	2.00e-84	305.00
IUUC-Oga-088684	Otolemur garnettii	82.19	0.00e+00	1596.00
IUUC-Oar-089428	Ovis aries	81.39	0.00e+00	1558.00
IUUC-Ptr-090529	Pan troglodytes	81.96	0.00e+00	1597.00
IUUC-Pan-091702	Papio anubis	82.07	0.00e+00	1600.00
IUUC-Psi-093969	Pelodiscus sinensis	82.22	0.00e+00	1562.00
IUUC-Pno-094871	Phaeosphaeria nodorum	39.16	3.00e-92	335.00
IUUC-Ppa-095834	Physcomitrella patens	42.73	2.00e-97	352.00
IUUC-Pfo-097364	Poecilia formosa	87.67	0.00e+00	1657.00
IUUC-Pab-098574	Pongo abelii	82.07	0.00e+00	1599.00
IUUC-Pop-099468	Populus trichocarpa	44.55	2.00e-101	365.00
IUUC-Pca-100525	Procavia capensis	79.28	6.00e-165	574.00
IUUC-Ppe-101641	Prunus persica	44.32	3.00e-101	365.00
IUUC-Pva-102365	Pteropus vampyrus	71.62	0.00e+00	1336.00
IUUC-Pgr-103465	Puccinia graminis	40.57	3.00e-100	362.00
IUUC-Ptt-103813	Puccinia triticina	38.09	1.00e-89	327.00
IUUC-Pte-104018	Pyrenophora teres	39.60	5.00e-92	334.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	39.82	2.00e-94	342.00
IUUC-Rno-105153	Rattus norvegicus	81.91	0.00e+00	1599.00
IUUC-Sha-107319	Sarcophilus harrisii	83.16	0.00e+00	1619.00
IUUC-Smo-109640	Selaginella moellendorffii	43.74	3.00e-98	355.00
IUUC-Sit-110598	Setaria italica	43.96	1.00e-98	356.00
IUUC-Sly-111706	Solanum lycopersicum	44.65	2.00e-101	365.00
IUUC-Stu-112894	Solanum tuberosum	34.47	3.00e-54	206.00
IUUC-Sar-113449	Sorex araneus	58.06	1.00e-125	444.00
IUUC-Sbi-114042	Sorghum bicolor	43.96	9.00e-99	357.00
IUUC-Sre-114958	Sporisorium reilianum	45.43	2.00e-107	382.00
IUUC-Ssc-115865	Sus scrofa	81.54	0.00e+00	1588.00
IUUC-Tgu-117225	Taeniopygia guttata	82.82	0.00e+00	1625.00
IUUC-Tru-118026	Takifugu rubripes	87.11	0.00e+00	1645.00
IUUC-Tsy-119407	Tarsius syrichta	69.62	0.00e+00	1298.00
IUUC-Tni-120234	Tetraodon nigroviridis	85.68	0.00e+00	1313.00
IUUC-Tca-121479	Theobroma cacao	44.09	1.00e-102	369.00
IUUC-Tae-125214	Triticum aestivum	42.54	4.00e-97	350.00
IUUC-Tbe-127708	Tupaia belangeri	68.65	0.00e+00	698.00
IUUC-Ttr-128667	Tursiops truncatus	81.43	0.00e+00	1589.00
IUUC-Uma-129355	Ustilago maydis	45.88	2.00e-107	383.00
IUUC-Vpa-130200	Vicugna pacos	81.37	0.00e+00	1538.00
IUUC-Vvi-131078	Vitis vinifera	43.86	6.00e-101	363.00
IUUC-Xtr-132176	Xenopus tropicalis	82.97	0.00e+00	1635.00
IUUC-Xma-133936	Xiphophorus maculatus	88.17	0.00e+00	969.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence