iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097978

Ensembl Protein ID

ENSPPYP00000004780.2

UniProt Accession

H2NG91; H2NG91_PONAB

Genbank Protein ID

ENSPPYP00000004780

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01151607

Gene Name

ING4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000004195.2	ENSPPYT00000004970.2	ENSPPYP00000004780.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/PHD	99.58	4.00e-109	391.00	IUUC-Hsa-046852

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

IENLPFELQR NFQLMRDLDQ RTEDLKAEID KLATEYMSSA RSLSSEEKLA LLKQIQEAYG 60
KCKEFGDDKV QLAMQTYEMV DKHIRRLDTD LARFEADLKE KQIESSDYDS SSSKGKKKGR 120

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Nucleotide Sequence
(Fasta)

CGCCCGCCAC CATACCTGGC TAATTTTTTT GTATTTTTAG TAGAGACGGG GTTTCACCAT 60
GTTAGCCAGG ATGGTCTCGA TCTCCTGACC TCGTGATCTG CTCTCCTCGG CCTCCCAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0007050--P:cell cycle arrest
GO:0006978--P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006260--P:DNA replication
GO:0043966--P:histone H3 acetylation
GO:0043983--P:histone H4-K12 acetylation
GO:0043981--P:histone H4-K5 acetylation
GO:0043982--P:histone H4-K8 acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0045926--P:negative regulation of growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	98.31	7.00e-116	409.00
IUUC-Atr-002906	Amborella trichopoda	31.69	4.00e-29	120.00
IUUC-Apl-004097	Anas platyrhynchos	96.19	4.00e-114	403.00
IUUC-Aca-004593	Anolis carolinensis	96.19	3.00e-114	404.00
IUUC-Ame-011133	Astyanax mexicanus	80.67	2.00e-105	374.00
IUUC-Bta-012699	Bos taurus	97.03	1.00e-115	408.00
IUUC-Bdi-014504	Brachypodium distachyon	35.39	2.00e-35	141.00
IUUC-Cja-019988	Callithrix jacchus	99.58	2.00e-110	391.00
IUUC-Cfa-021282	Canis familiaris	98.73	2.00e-109	388.00
IUUC-Cpo-022011	Cavia porcellus	98.73	9.00e-120	422.00
IUUC-Csa-023203	Chlorocebus sabaeus	99.58	2.00e-110	391.00
IUUC-Cin-025479	Ciona intestinalis	60.44	7.00e-71	259.00
IUUC-Csv-026288	Ciona savignyi	53.94	1.00e-66	246.00
IUUC-Dre-028264	Danio rerio	77.73	7.00e-104	369.00
IUUC-Dno-029766	Dasypus novemcinctus	99.15	7.00e-110	389.00
IUUC-Dor-031136	Dipodomys ordii	93.47	2.00e-91	328.00
IUUC-Dme-032200	Drosophila melanogaster	82.67	5.00e-38	151.00
IUUC-Eca-033565	Equus caballus	98.73	1.00e-119	422.00
IUUC-Eeu-034948	Erinaceus europaeus	81.36	4.00e-94	337.00
IUUC-Fca-036368	Felis catus	99.15	5.00e-110	389.00
IUUC-Fal-037120	Ficedula albicollis	96.19	9.00e-114	402.00
IUUC-Gmo-038982	Gadus morhua	79.75	7.00e-105	372.00
IUUC-Gga-040771	Gallus gallus	96.19	3.00e-114	404.00
IUUC-Gac-042184	Gasterosteus aculeatus	79.32	2.00e-103	368.00
IUUC-Gma-044339	Glycine max	29.10	7.00e-30	123.00
IUUC-Ggo-045559	Gorilla gorilla	99.58	2.00e-110	391.00
IUUC-Hsa-046852	Homo sapiens	99.58	2.00e-110	391.00
IUUC-Hvu-047046	Hordeum vulgare	35.66	3.00e-34	138.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	98.31	2.00e-119	421.00
IUUC-Lpe-050822	Leersia perrieri	34.16	5.00e-34	137.00
IUUC-Loc-052725	Lepisosteus oculatus	61.44	2.00e-74	271.00
IUUC-Laf-054057	Loxodonta africana	99.15	5.00e-110	389.00
IUUC-Mcc-055212	Macaca mulatta	92.86	2.00e-104	371.00
IUUC-Meu-056511	Macropus eugenii	97.76	1.00e-110	392.00
IUUC-Mga-059967	Meleagris gallopavo	96.19	4.00e-114	403.00
IUUC-Mmr-060843	Microcebus murinus	97.03	7.00e-116	409.00
IUUC-Mdo-062357	Monodelphis domestica	97.88	3.00e-119	420.00
IUUC-Mmu-064093	Mus musculus	98.73	9.00e-120	422.00
IUUC-Mac-064625	Musa acuminata	34.26	8.00e-33	133.00
IUUC-Mpu-066923	Mustela putorius furo	86.86	9.00e-87	312.00
IUUC-Mlu-067754	Myotis lucifugus	90.79	6.00e-108	383.00
IUUC-Nle-069062	Nomascus leucogenys	99.58	2.00e-110	391.00
IUUC-Opr-070207	Ochotona princeps	91.95	4.00e-109	386.00
IUUC-Ont-072446	Oreochromis niloticus	80.17	1.00e-103	369.00
IUUC-Oan-073652	Ornithorhynchus anatinus	64.83	7.00e-79	286.00
IUUC-Ocu-074235	Oryctolagus cuniculus	98.73	2.00e-109	388.00
IUUC-Obr-076266	Oryza brachyantha	34.98	6.00e-33	134.00
IUUC-Ogl-077118	Oryza glaberrima	32.79	2.00e-32	132.00
IUUC-Ome-081291	Oryza meridionalis	33.20	5.00e-33	134.00
IUUC-Opu-084171	Oryza punctata	33.47	4.00e-33	135.00
IUUC-Osa-085563	Oryza sativa	33.20	5.00e-33	134.00
IUUC-Ola-086429	Oryzias latipes	75.11	1.00e-94	338.00
IUUC-Oga-089123	Otolemur garnettii	99.15	5.00e-110	389.00
IUUC-Oar-089524	Ovis aries	97.03	1.00e-115	408.00
IUUC-Ptr-090908	Pan troglodytes	99.15	5.00e-110	389.00
IUUC-Pan-092837	Papio anubis	98.73	2.00e-116	411.00
IUUC-Psi-093828	Pelodiscus sinensis	95.71	2.00e-111	394.00
IUUC-Ppa-096009	Physcomitrella patens	32.93	1.00e-28	119.00
IUUC-Pfo-096617	Poecilia formosa	79.75	1.00e-103	369.00
IUUC-Pca-100475	Procavia capensis	64.68	9.00e-75	272.00
IUUC-Ppe-101441	Prunus persica	32.66	1.00e-32	132.00
IUUC-Pva-102325	Pteropus vampyrus	98.73	1.00e-119	422.00
IUUC-Rno-105178	Rattus norvegicus	93.64	2.00e-125	441.00
IUUC-Sha-106773	Sarcophilus harrisii	97.88	3.00e-119	421.00
IUUC-Smo-109441	Selaginella moellendorffii	32.37	4.00e-35	140.00
IUUC-Sit-109827	Setaria italica	34.16	2.00e-32	132.00
IUUC-Sly-111750	Solanum lycopersicum	34.16	1.00e-32	132.00
IUUC-Stu-112250	Solanum tuberosum	34.16	1.00e-32	132.00
IUUC-Sbi-114826	Sorghum bicolor	35.39	2.00e-33	135.00
IUUC-Ssc-115797	Sus scrofa	95.76	4.00e-102	363.00
IUUC-Tgu-117270	Taeniopygia guttata	96.19	3.00e-114	404.00
IUUC-Tru-118253	Takifugu rubripes	78.99	7.00e-104	369.00
IUUC-Tni-120024	Tetraodon nigroviridis	56.36	8.00e-61	226.00
IUUC-Tae-123043	Triticum aestivum	34.41	8.00e-34	137.00
IUUC-Tbe-127558	Tupaia belangeri	98.31	7.00e-116	409.00
IUUC-Ttr-128300	Tursiops truncatus	98.18	9.00e-63	233.00
IUUC-Xtr-132189	Xenopus tropicalis	67.80	8.00e-80	289.00
IUUC-Xma-133297	Xiphophorus maculatus	61.86	3.00e-74	271.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence