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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046920
UUCD1 version UUC-HoS-01006
Ensembl Protein ID ENSP00000437464.1
UniProt Accession Q9UF56; A1A4E3; FXL17_HUMAN
Genbank Protein ID BAC86658.1; CAB63737.2; EAW49061.1; AAI26145.1; AAI26147.1
Protein Name F-box/LRR-repeat protein 17; F-box and leucine-rich repeat protein 17; F-box only protein 13
Genbank Nucleotide ID AK126722; AL133602; AC008462; BC126144; BC126146
Gene Name FBXL17; FBL17; FBX13; FBXO13
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000145743.15 ENST00000496714.1 ENSP00000418111.1
ENSG00000145743.15 ENST00000542267.5 ENSP00000437464.1
ENSG00000145743.15 ENST00000619412.4 ENSP00000481439.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDPINAHINTMentha
InWeb_IM
Disease-associated Information
ClinVarGWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box F-box 24035498
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
 Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Protein Sequence
(Fasta)
MGHLLSKEPR NRPSQKRPRC CSWCRRRRPL LRLPRRTPAK VPPQPAAPRS RDCFFRGPCM 60
LCFIVHSPGA PAPAGPEEEP PLSPPPRDGA YAAASSSQHL ARRYAALAAE DCAAAARRFL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046920|E3,F-box|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGAGTCGCGG GTGCGCGCGC CGGCGGCGGA TCCGCAGTTA AAATGGTCCG AGCGGGACCC 60
GGCCTTTCCC CGGCCGCTCC GCTGACTGAC TGAGCCGGCT GGCCGGGCCC GGACTGGTCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046920|E3,F-box|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp
PROSITE

PS50181--FBOX
Pfam

PF12937--F-box-like
PF13516--LRR_6
SMART

SM00256--FBOX
SM00367--LRR_CC
KEGG hsa:64839
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002032 Ailuropoda melanoleuca 99.46 0.00e+00 729.00
IUUC-Apl-003766 Anas platyrhynchos 92.75 8.00e-176 609.00
IUUC-Aca-005107 Anolis carolinensis 89.96 7.00e-147 513.00
IUUC-Acl-008301 Aspergillus clavatus 28.80 6.00e-38 152.00
IUUC-Afl-008738 Aspergillus flavus 29.21 3.00e-35 143.00
IUUC-Ani-009369 Aspergillus nidulans 30.05 2.00e-38 154.00
IUUC-Ang-009719 Aspergillus niger 28.02 6.00e-36 145.00
IUUC-Aor-009957 Aspergillus oryzae 28.65 4.00e-35 142.00
IUUC-Ame-011514 Astyanax mexicanus 75.27 5.00e-82 298.00
IUUC-Bta-013098 Bos taurus 97.86 2.00e-78 283.00
IUUC-Cja-019467 Callithrix jacchus 95.60 0.00e+00 1023.00
IUUC-Cfa-020024 Canis familiaris 96.17 0.00e+00 741.00
IUUC-Cpo-021473 Cavia porcellus 97.92 3.00e-139 487.00
IUUC-Csa-023932 Chlorocebus sabaeus 96.48 0.00e+00 806.00
IUUC-Cho-024827 Choloepus hoffmanni 98.78 0.00e+00 630.00
IUUC-Dre-028302 Danio rerio 41.81 1.00e-62 233.00
IUUC-Dor-030648 Dipodomys ordii 85.37 2.00e-148 518.00
IUUC-Ete-032460 Echinops telfairi 85.21 3.00e-119 421.00
IUUC-Eca-034004 Equus caballus 99.67 1.00e-170 592.00
IUUC-Eeu-034554 Erinaceus europaeus 81.16 5.00e-130 457.00
IUUC-Fca-035592 Felis catus 99.67 1.00e-170 592.00
IUUC-Fal-036750 Ficedula albicollis 92.19 0.00e+00 732.00
IUUC-Gmo-038685 Gadus morhua 70.33 8.00e-74 269.00
IUUC-Gga-040203 Gallus gallus 90.86 0.00e+00 709.00
IUUC-Lch-049535 Latimeria chalumnae 80.08 4.00e-123 434.00
IUUC-Loc-052238 Lepisosteus oculatus 75.00 2.00e-82 298.00
IUUC-Mcc-054939 Macaca mulatta 97.16 0.00e+00 1051.00
IUUC-Meu-056168 Macropus eugenii 74.38 6.00e-83 300.00
IUUC-Mor-057058 Magnaporthe oryzae 25.33 2.00e-30 127.00
IUUC-Mpo-057320 Magnaporthe poae 27.89 6.00e-34 139.00
IUUC-Mmr-061483 Microcebus murinus 99.67 1.00e-170 592.00
IUUC-Mdo-062006 Monodelphis domestica 95.54 0.00e+00 755.00
IUUC-Mpu-065771 Mustela putorius furo 99.73 0.00e+00 729.00
IUUC-Mlu-067338 Myotis lucifugus 99.15 1.00e-138 485.00
IUUC-Nfi-068473 Neosartorya fischeri 28.37 1.00e-34 141.00
IUUC-Opr-070744 Ochotona princeps 88.12 1.00e-145 509.00
IUUC-Ola-086864 Oryzias latipes 70.93 6.00e-72 263.00
IUUC-Oga-088756 Otolemur garnettii 98.13 0.00e+00 833.00
IUUC-Oar-089491 Ovis aries 98.35 3.00e-167 580.00
IUUC-Ptr-091120 Pan troglodytes 99.43 0.00e+00 1051.00
IUUC-Pan-092746 Papio anubis 98.06 0.00e+00 810.00
IUUC-Psi-093402 Pelodiscus sinensis 93.99 2.00e-177 614.00
IUUC-Pma-094211 Petromyzon marinus 50.00 4.00e-43 167.00
IUUC-Pca-100179 Procavia capensis 88.62 5.00e-149 520.00
IUUC-Pva-102200 Pteropus vampyrus 85.23 2.00e-158 552.00
IUUC-Rno-105491 Rattus norvegicus 97.36 1.00e-166 578.00
IUUC-Sha-107408 Sarcophilus harrisii 95.38 5.00e-97 346.00
IUUC-Sar-113484 Sorex araneus 73.17 6.00e-127 447.00
IUUC-Ssc-116229 Sus scrofa 91.88 2.00e-174 605.00
IUUC-Tgu-116754 Taeniopygia guttata 90.48 9.00e-162 562.00
IUUC-Tsy-119390 Tarsius syrichta 99.09 0.00e+00 633.00
IUUC-Tni-120505 Tetraodon nigroviridis 71.68 1.00e-73 268.00
IUUC-Ttr-129011 Tursiops truncatus 82.46 3.00e-157 547.00
Created Date 25-Jun-2017

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