iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060151

UUCD1 version

UUC-MeG-00195

Ensembl Protein ID

ENSMGAP00000003765.1

UniProt Accession

G1MXY8; G1MXY8_MELGA

Protein Name

Uncharacterized protein

Gene Name

HERC4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000003907.2	ENSMGAT00000004472.1	ENSMGAP00000003765.1
ENSMGAG00000003907.2	ENSMGAT00000019337.1	ENSMGAP00000019490.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-37	129.3	732	891

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpl 92
           d kk l+v fvgEe++d gGv +ef+ l+++el +p++g+f+y e+++  ++ +++      e  +lF+++G+++g+a+++  ++dl++
   Q: 732  DYKKPLKVIFVGEEAVDVGGVRKEFFLLIMRELLDPKYGMFRYYEESRLIWFSDKTF-----EDSDLFHLIGVVCGLAIYNFTIVDLHF 815
           78999***********************************************98877.....689************************ PP
   S: 93   sksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + ++yk+ll+kk sl+dl+e++p++ + +++++++ e+diee+ ++l+f+++ e++g+t+ +eL+p+G++ipV ++N
   Q: 816  PLALYKKLLNKKPSLDDLKELMPDVGRGMQQLLDYPEDDIEEA-FCLNFTITVENFGTTEIKELVPNGADIPVVKQN 891
           *************************************9**998.*****************************9988 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MLCWGNASFG QLGLGGIDEE IVLEPRKSDF FLNKRIRDVG CGLRHTVFVL DDGTVYTCGC 60
NDLGQLGHEK ARKRPEHVGA LDAQNIVAVS CGEAHTLALN DKGQVYAWGL ATDGQLGLPG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGTGCT GGGGAAATGC ATCGTTTGGA CAACTTGGAC TGGGTGGAAT TGATGAAGAG 60
ATTGTTTTAG AACCCAGAAA AAGTGACTTT TTCTTAAATA AAAGGATCAG AGATGTGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0005829--C:cytosol
GO:0001650--C:fibrillar center
GO:0004842--F:ubiquitin-protein transferase activity
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001666	Ailuropoda melanoleuca	87.44	0.00e+00	1515.00
IUUC-Apl-003295	Anas platyrhynchos	98.21	0.00e+00	1760.00
IUUC-Aca-004336	Anolis carolinensis	85.14	0.00e+00	1544.00
IUUC-Ame-010768	Astyanax mexicanus	71.03	0.00e+00	1286.00
IUUC-Bta-013279	Bos taurus	87.56	0.00e+00	1520.00
IUUC-Bdi-014791	Brachypodium distachyon	38.69	3.00e-52	198.00
IUUC-Cja-019023	Callithrix jacchus	87.33	0.00e+00	1514.00
IUUC-Cfa-021074	Canis familiaris	87.56	0.00e+00	1519.00
IUUC-Cpo-021461	Cavia porcellus	84.79	0.00e+00	1467.00
IUUC-Cre-023014	Chlamydomonas reinhardtii	36.76	1.00e-48	186.00
IUUC-Csa-024261	Chlorocebus sabaeus	87.78	0.00e+00	1523.00
IUUC-Cho-024513	Choloepus hoffmanni	67.15	0.00e+00	1058.00
IUUC-Dre-028829	Danio rerio	72.07	0.00e+00	1240.00
IUUC-Dno-029445	Dasypus novemcinctus	86.70	0.00e+00	1180.00
IUUC-Ete-033072	Echinops telfairi	76.77	0.00e+00	1297.00
IUUC-Eca-033317	Equus caballus	86.21	0.00e+00	1493.00
IUUC-Fca-035682	Felis catus	86.66	0.00e+00	1496.00
IUUC-Fal-036969	Ficedula albicollis	95.06	0.00e+00	1707.00
IUUC-Gmo-038671	Gadus morhua	70.08	0.00e+00	1258.00
IUUC-Gga-041174	Gallus gallus	99.66	0.00e+00	1778.00
IUUC-Gac-042600	Gasterosteus aculeatus	70.76	0.00e+00	1217.00
IUUC-Gma-043616	Glycine max	36.31	3.00e-51	196.00
IUUC-Ggo-044589	Gorilla gorilla	87.78	0.00e+00	1546.00
IUUC-Hsa-046772	Homo sapiens	87.56	0.00e+00	1541.00
IUUC-Lch-050147	Latimeria chalumnae	80.61	0.00e+00	1396.00
IUUC-Lpe-051165	Leersia perrieri	33.53	1.00e-44	173.00
IUUC-Loc-052684	Lepisosteus oculatus	77.24	0.00e+00	1364.00
IUUC-Laf-053844	Loxodonta africana	86.66	0.00e+00	1503.00
IUUC-Mcc-055531	Macaca mulatta	85.48	0.00e+00	1511.00
IUUC-Mmr-060954	Microcebus murinus	87.78	0.00e+00	1526.00
IUUC-Mdo-062246	Monodelphis domestica	84.46	0.00e+00	1349.00
IUUC-Mmu-063369	Mus musculus	85.54	0.00e+00	1519.00
IUUC-Mpu-065936	Mustela putorius furo	87.03	0.00e+00	1367.00
IUUC-Mlu-067326	Myotis lucifugus	87.22	0.00e+00	1514.00
IUUC-Nle-069453	Nomascus leucogenys	86.66	0.00e+00	1495.00
IUUC-Ont-071720	Oreochromis niloticus	71.64	0.00e+00	1248.00
IUUC-Oan-073464	Ornithorhynchus anatinus	87.39	0.00e+00	1396.00
IUUC-Ocu-074207	Oryctolagus cuniculus	84.42	0.00e+00	1356.00
IUUC-Oba-075262	Oryza barthii	34.42	3.00e-45	175.00
IUUC-Obr-076115	Oryza brachyantha	33.94	8.00e-44	170.00
IUUC-Ogl-077586	Oryza glaberrima	34.42	2.00e-45	176.00
IUUC-Ogu-078796	Oryza glumaepatula	34.42	3.00e-45	175.00
IUUC-Oin-079298	Oryza indica	34.42	2.00e-45	176.00
IUUC-Olo-080768	Oryza longistaminata	38.59	3.00e-52	198.00
IUUC-Ome-081908	Oryza meridionalis	33.43	1.00e-45	176.00
IUUC-Oni-082049	Oryza nivara	34.42	3.00e-45	175.00
IUUC-Opu-083608	Oryza punctata	34.63	4.00e-46	178.00
IUUC-Oru-084712	Oryza rufipogon	34.42	3.00e-45	175.00
IUUC-Osa-086078	Oryza sativa	34.42	3.00e-45	175.00
IUUC-Ola-086762	Oryzias latipes	70.29	0.00e+00	1195.00
IUUC-Oga-088435	Otolemur garnettii	87.78	0.00e+00	1527.00
IUUC-Oar-089233	Ovis aries	87.67	0.00e+00	1521.00
IUUC-Ptr-091368	Pan troglodytes	87.78	0.00e+00	1546.00
IUUC-Pan-092300	Papio anubis	87.78	0.00e+00	1523.00
IUUC-Psi-093406	Pelodiscus sinensis	90.70	0.00e+00	1647.00
IUUC-Pma-094113	Petromyzon marinus	67.92	0.00e+00	886.00
IUUC-Pfo-097021	Poecilia formosa	70.27	0.00e+00	1281.00
IUUC-Pab-098327	Pongo abelii	87.67	0.00e+00	1544.00
IUUC-Pca-101075	Procavia capensis	82.98	0.00e+00	735.00
IUUC-Pva-102909	Pteropus vampyrus	79.04	0.00e+00	1321.00
IUUC-Rno-105457	Rattus norvegicus	86.77	0.00e+00	1546.00
IUUC-Sha-106632	Sarcophilus harrisii	85.76	0.00e+00	1520.00
IUUC-Sit-110415	Setaria italica	37.34	1.00e-51	197.00
IUUC-Sar-113679	Sorex araneus	77.50	0.00e+00	1013.00
IUUC-Tgu-116849	Taeniopygia guttata	89.46	0.00e+00	1580.00
IUUC-Tru-118206	Takifugu rubripes	69.92	0.00e+00	1193.00
IUUC-Tsy-119521	Tarsius syrichta	76.01	0.00e+00	1238.00
IUUC-Tni-120233	Tetraodon nigroviridis	69.69	0.00e+00	1169.00
IUUC-Tbe-127941	Tupaia belangeri	71.69	0.00e+00	988.00
IUUC-Ttr-128926	Tursiops truncatus	86.58	0.00e+00	1058.00
IUUC-Vpa-130448	Vicugna pacos	87.00	0.00e+00	1511.00
IUUC-Xtr-132719	Xenopus tropicalis	67.11	0.00e+00	1079.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence