iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132144

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01035834

Gene Name

klhl41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000018861.3	ENSXETT00000040965.3	ENSXETP00000040965.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.00e-17	62.5	57	123
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.70e-09	36.8	155	185

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D+ l+ g +  ++h+++Laa+S++F+  fl++ +e k k+ +e++ v+p+ ++a+lk+lY+  +d+n+
   Q: 57   DCFLKAGSKSLPCHRLILAACSPYFREFFLSDESEEK-KKNMELDNVEPSTMEAILKYLYSADIDLND 123
           99********************************999.9999***********************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Ncl+i+r++ l+dcp+L+  a+d++++ F
   Q: 155  PANCLAIFRLGLLLDCPRLAVTARDYVCDRF 185
           67***************************98 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

ALGAARSRGL SVSPANACSS GNKMDPTGEI KDELRLYQST LLQDGLKELL DENKFVDCFL 60
KAGSKSLPCH RLILAACSPY FREFFLSDES EEKKKNMELD NVEPSTMEAI LKYLYSADID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTTGGGAG CTGCTAGAAG CAGAGGCCTC TCCGTTTCTC CTGCAAACGC CTGCTCTTCA 60
GGAAACAAAA AAAAATGGAT CCCACCGGGG AAATAAAGGA TGAACTTAGG CTTTACCAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0031430--C:M band
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002167	Ailuropoda melanoleuca	75.95	0.00e+00	974.00
IUUC-Apl-003866	Anas platyrhynchos	75.12	0.00e+00	956.00
IUUC-Ame-010909	Astyanax mexicanus	60.82	0.00e+00	795.00
IUUC-Bta-012925	Bos taurus	76.24	0.00e+00	977.00
IUUC-Cja-019348	Callithrix jacchus	76.24	0.00e+00	978.00
IUUC-Cfa-020782	Canis familiaris	75.93	0.00e+00	983.00
IUUC-Cpo-021825	Cavia porcellus	75.91	0.00e+00	971.00
IUUC-Csa-023184	Chlorocebus sabaeus	75.82	0.00e+00	828.00
IUUC-Cin-025237	Ciona intestinalis	29.40	1.00e-69	257.00
IUUC-Dre-028278	Danio rerio	59.87	0.00e+00	796.00
IUUC-Dno-029516	Dasypus novemcinctus	76.57	0.00e+00	981.00
IUUC-Dor-030850	Dipodomys ordii	73.48	0.00e+00	630.00
IUUC-Ete-032697	Echinops telfairi	75.25	0.00e+00	946.00
IUUC-Eca-033714	Equus caballus	76.11	0.00e+00	978.00
IUUC-Eeu-035245	Erinaceus europaeus	76.49	0.00e+00	895.00
IUUC-Gmo-039392	Gadus morhua	58.62	0.00e+00	759.00
IUUC-Gga-041106	Gallus gallus	75.74	0.00e+00	980.00
IUUC-Gac-042252	Gasterosteus aculeatus	59.11	0.00e+00	783.00
IUUC-Ggo-044817	Gorilla gorilla	76.28	0.00e+00	979.00
IUUC-Hsa-046620	Homo sapiens	76.40	0.00e+00	978.00
IUUC-Lch-050477	Latimeria chalumnae	67.49	0.00e+00	862.00
IUUC-Lpe-050853	Leersia perrieri	27.78	4.00e-09	55.50
IUUC-Loc-051955	Lepisosteus oculatus	68.20	0.00e+00	915.00
IUUC-Laf-053500	Loxodonta africana	76.57	0.00e+00	979.00
IUUC-Mcc-055316	Macaca mulatta	76.40	0.00e+00	979.00
IUUC-Mtr-058084	Medicago truncatula	29.53	2.00e-11	62.80
IUUC-Mmr-061444	Microcebus murinus	76.40	0.00e+00	979.00
IUUC-Mmu-064147	Mus musculus	75.41	0.00e+00	978.00
IUUC-Mlu-067481	Myotis lucifugus	75.25	0.00e+00	967.00
IUUC-Nle-069339	Nomascus leucogenys	76.57	0.00e+00	979.00
IUUC-Opr-070703	Ochotona princeps	76.40	0.00e+00	942.00
IUUC-Ont-072420	Oreochromis niloticus	61.18	0.00e+00	819.00
IUUC-Oan-073476	Ornithorhynchus anatinus	76.40	0.00e+00	981.00
IUUC-Ocu-074248	Oryctolagus cuniculus	76.26	0.00e+00	989.00
IUUC-Ola-086361	Oryzias latipes	60.23	0.00e+00	782.00
IUUC-Oar-090349	Ovis aries	76.07	0.00e+00	971.00
IUUC-Pan-092069	Papio anubis	76.57	0.00e+00	980.00
IUUC-Psi-093671	Pelodiscus sinensis	76.07	0.00e+00	944.00
IUUC-Pfo-096122	Poecilia formosa	61.51	0.00e+00	811.00
IUUC-Pab-098711	Pongo abelii	76.57	0.00e+00	978.00
IUUC-Pca-100495	Procavia capensis	69.64	0.00e+00	868.00
IUUC-Pva-102401	Pteropus vampyrus	76.07	0.00e+00	977.00
IUUC-Rno-105969	Rattus norvegicus	75.91	0.00e+00	980.00
IUUC-Ssl-108403	Sclerotinia sclerotiorum	25.88	5.00e-07	47.80
IUUC-Sar-113405	Sorex araneus	74.92	0.00e+00	951.00
IUUC-Tgu-116725	Taeniopygia guttata	75.25	0.00e+00	984.00
IUUC-Tru-117743	Takifugu rubripes	59.38	0.00e+00	790.00
IUUC-Tsy-119225	Tarsius syrichta	72.11	0.00e+00	905.00
IUUC-Tni-120547	Tetraodon nigroviridis	61.96	0.00e+00	802.00
IUUC-Ttr-128645	Tursiops truncatus	76.57	0.00e+00	981.00
IUUC-Vpa-130714	Vicugna pacos	76.24	0.00e+00	979.00
IUUC-Xma-133860	Xiphophorus maculatus	61.35	0.00e+00	813.00
IUUC-Yli-134535	Yarrowia lipolytica	23.03	1.00e-07	50.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence