iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UFD/PB1	26.98	3.00e-20	96.30	IUUC-Sce-106197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MEAPGSGSGD GGDPGGDGAH PDARPSSGPC AAARDSERQL RLRLCVLNEI LATERDYVGT 60
LLLFSAFLQR IRQNVADSVD KGLTEENVKI LFSNIEDILE VHKDFLAALE YCLHPEPQSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCGC CCGGCAGCGG TAGTGGCGAT GGCGGCGGGA CCCAGGCGGG GACGGTGCGC 60
ATCCCGATGC TCGCGTCCCA GCTCCGGGCC ATGCGCGGCC GCCCGCGACT CGGAGCGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR000591--DEP_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR001478--PDZ
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50186--DEP
PS00741--DH_1
PS50010--DH_2
PS50106--PDZ
PS50003--PH_DOMAIN

Pfam

PF00610--DEP
PF00621--RhoGEF

SMART

SM00049--DEP
SM00228--PDZ
SM00233--PH
SM00325--RhoGEF

Gene Ontology

GO:0005829--C:cytosol
GO:0043198--C:dendritic shaft
GO:0030426--C:growth cone
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0005543--F:phospholipid binding
GO:0030676--F:Rac guanyl-nucleotide exchange factor activity
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0006469--P:negative regulation of protein kinase activity
GO:0032007--P:negative regulation of TOR signaling
GO:0030593--P:neutrophil chemotaxis
GO:0030335--P:positive regulation of cell migration
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0072593--P:reactive oxygen species metabolic process
GO:0030833--P:regulation of actin filament polymerization
GO:0050773--P:regulation of dendrite development
GO:0035023--P:regulation of Rho protein signal transduction
GO:0030217--P:T cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002073	Ailuropoda melanoleuca	33.25	2.00e-49	191.00
IUUC-Apl-004117	Anas platyrhynchos	34.16	1.00e-49	191.00
IUUC-Aca-004793	Anolis carolinensis	34.25	7.00e-45	176.00
IUUC-Ago-008003	Ashbya gossypii	27.20	9.00e-18	85.50
IUUC-Acl-008142	Aspergillus clavatus	24.05	1.00e-18	89.00
IUUC-Ani-009276	Aspergillus nidulans	24.86	2.00e-19	91.30
IUUC-Ate-010338	Aspergillus terreus	25.14	3.00e-17	84.30
IUUC-Ame-010682	Astyanax mexicanus	32.97	5.00e-48	187.00
IUUC-Bgr-012058	Blumeria graminis	25.48	3.00e-16	80.90
IUUC-Bta-013253	Bos taurus	37.54	1.00e-53	204.00
IUUC-Bci-013634	Botrytis cinerea	24.13	2.00e-16	81.60
IUUC-Cja-019555	Callithrix jacchus	34.66	4.00e-46	179.00
IUUC-Cfa-020578	Canis familiaris	32.99	2.00e-45	178.00
IUUC-Cpo-021726	Cavia porcellus	34.26	2.00e-17	85.10
IUUC-Csa-023331	Chlorocebus sabaeus	37.25	5.00e-54	205.00
IUUC-Cho-025069	Choloepus hoffmanni	71.37	0.00e+00	768.00
IUUC-Cin-025453	Ciona intestinalis	34.44	9.00e-47	181.00
IUUC-Csv-025922	Ciona savignyi	32.68	1.00e-45	178.00
IUUC-Dre-028197	Danio rerio	36.78	3.00e-48	189.00
IUUC-Dno-029679	Dasypus novemcinctus	33.91	3.00e-44	174.00
IUUC-Dor-030739	Dipodomys ordii	37.22	2.00e-52	200.00
IUUC-Dse-031545	Dothistroma septosporum	24.23	6.00e-13	70.10
IUUC-Ete-032545	Echinops telfairi	84.01	0.00e+00	713.00
IUUC-Eca-034299	Equus caballus	33.62	1.00e-47	184.00
IUUC-Eeu-034720	Erinaceus europaeus	62.67	0.00e+00	965.00
IUUC-Fca-036416	Felis catus	32.47	2.00e-44	174.00
IUUC-Fal-037035	Ficedula albicollis	34.44	2.00e-50	194.00
IUUC-Gmo-039587	Gadus morhua	35.82	3.00e-52	199.00
IUUC-Ggr-039728	Gaeumannomyces graminis	26.13	2.00e-11	64.70
IUUC-Gga-040841	Gallus gallus	37.06	4.00e-54	206.00
IUUC-Gac-042498	Gasterosteus aculeatus	36.39	6.00e-52	198.00
IUUC-Ggo-044700	Gorilla gorilla	57.18	0.00e+00	1775.00
IUUC-Hsa-045681	Homo sapiens	33.42	5.00e-51	196.00
IUUC-Itr-048380	Ictidomys tridecemlineatus	33.50	1.00e-45	177.00
IUUC-Kpa-049278	Komagataella pastoris	26.10	6.00e-19	89.70
IUUC-Lch-049639	Latimeria chalumnae	35.34	1.00e-53	204.00
IUUC-Loc-051994	Lepisosteus oculatus	37.07	3.00e-54	206.00
IUUC-Laf-054307	Loxodonta africana	32.72	4.00e-48	186.00
IUUC-Mcc-055305	Macaca mulatta	37.00	6.00e-37	148.00
IUUC-Meu-056376	Macropus eugenii	37.60	1.00e-55	211.00
IUUC-Mla-059044	Melampsora laricipopulina	25.27	2.00e-22	101.00
IUUC-Mga-059644	Meleagris gallopavo	34.44	3.00e-50	194.00
IUUC-Mvi-060486	Microbotryum violaceum	29.35	2.00e-26	114.00
IUUC-Mmr-061664	Microcebus murinus	33.77	1.00e-46	182.00
IUUC-Mdo-062404	Monodelphis domestica	58.27	0.00e+00	1806.00
IUUC-Mmu-063143	Mus musculus	55.81	0.00e+00	1752.00
IUUC-Mpu-066851	Mustela putorius furo	33.05	2.00e-43	171.00
IUUC-Mlu-066956	Myotis lucifugus	32.49	5.00e-45	176.00
IUUC-Ncr-068819	Neurospora crassa	27.07	5.00e-12	67.00
IUUC-Nle-069174	Nomascus leucogenys	90.61	2.00e-127	448.00
IUUC-Opr-070209	Ochotona princeps	34.30	1.00e-45	178.00
IUUC-Ont-072637	Oreochromis niloticus	36.39	6.00e-52	198.00
IUUC-Oan-073722	Ornithorhynchus anatinus	34.29	4.00e-46	179.00
IUUC-Ocu-074885	Oryctolagus cuniculus	33.76	5.00e-46	180.00
IUUC-Ola-087155	Oryzias latipes	51.49	0.00e+00	1536.00
IUUC-Olu-087672	Ostreococcus lucimarinus	29.82	1.80e+00	26.60
IUUC-Oga-088758	Otolemur garnettii	33.77	4.00e-50	193.00
IUUC-Oar-089923	Ovis aries	37.25	3.00e-53	202.00
IUUC-Ptr-091555	Pan troglodytes	33.51	2.00e-49	190.00
IUUC-Pan-092037	Papio anubis	33.77	6.00e-50	193.00
IUUC-Psi-093865	Pelodiscus sinensis	34.25	1.00e-50	195.00
IUUC-Pno-095127	Phaeosphaeria nodorum	22.82	7.00e-11	63.20
IUUC-Pfo-096918	Poecilia formosa	55.79	0.00e+00	1734.00
IUUC-Pab-097910	Pongo abelii	33.77	5.00e-50	193.00
IUUC-Pca-100891	Procavia capensis	50.44	3.00e-152	533.00
IUUC-Pva-102967	Pteropus vampyrus	38.26	3.00e-42	166.00
IUUC-Pgr-103400	Puccinia graminis	26.13	4.00e-26	114.00
IUUC-Sce-106197	Saccharomyces cerevisiae	29.25	6.00e-20	93.20
IUUC-Sha-107592	Sarcophilus harrisii	33.83	1.00e-48	188.00
IUUC-Sja-107728	Schizosaccharomyces japonicus	25.89	3.00e-13	70.90
IUUC-Spo-108284	Schizosaccharomyces pombe	26.24	4.00e-25	110.00
IUUC-Ssl-108541	Sclerotinia sclerotiorum	24.42	8.00e-17	82.80
IUUC-Sar-113369	Sorex araneus	35.65	3.00e-35	142.00
IUUC-Sbi-114741	Sorghum bicolor	27.36	4.70e-01	30.00
IUUC-Sre-115126	Sporisorium reilianum	31.16	4.00e-29	124.00
IUUC-Ssc-115967	Sus scrofa	33.80	6.00e-14	73.60
IUUC-Tgu-117088	Taeniopygia guttata	38.40	3.00e-54	206.00
IUUC-Tru-118716	Takifugu rubripes	68.61	0.00e+00	2211.00
IUUC-Tsy-118846	Tarsius syrichta	34.38	3.00e-41	162.00
IUUC-Tni-120887	Tetraodon nigroviridis	55.14	0.00e+00	1721.00
IUUC-Tme-127216	Tuber melanosporum	26.63	6.00e-23	103.00
IUUC-Tbe-127248	Tupaia belangeri	49.23	1.00e-137	484.00
IUUC-Ttr-128429	Tursiops truncatus	34.09	2.00e-18	88.60
IUUC-Uma-129594	Ustilago maydis	30.04	2.00e-27	118.00
IUUC-Vpa-130750	Vicugna pacos	62.34	0.00e+00	1079.00
IUUC-Xtr-132676	Xenopus tropicalis	36.68	1.00e-53	204.00
IUUC-Xma-133871	Xiphophorus maculatus	55.35	0.00e+00	1688.00
IUUC-Yli-134423	Yarrowia lipolytica	27.83	1.00e-28	121.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence