iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025188

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Beta-transducin repeat-containing homologue protein

Genbank Nucleotide ID

EAAA01002171

Gene Name

Ci-betaTrCP; betaTrCP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000009295.3	ENSCINT00000018885.3	ENSCINP00000018885.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-57	187.9	520	556
UBD/Beta-Prp	7.60e-67	225.4	436	598

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvllk 37
           gH++ v+c++f d +++vsG++Dg+ikvWDl    +++
   Q: 520  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLQAALDPR 556
           8**********.44****************98877765 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetls 134
           r l gh a+v+ v+f+++  ++v++s Drtikvw+  t++ v+tl+gh + + +l++      +vsGs+d+tir+wd+e g cl+ +l+
   Q: 436  RVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWNTLTCEFVRTLNGHRRGIACLQYRD--RLVVSGSSDNTIRLWDIEFGACLR-ILE 519
           45799**********999..8************************************99..9**********************9.*** PP
   S: 135  ghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           gh+++v+c++++   + +vsG++D+++++Wdl         ++  +lrtl + ht++v  l+fd+  +++vs s+d ++ +wd+
   Q: 520  GHEELVRCIRFDN--KRIVSGAYDGKIKVWDLqaaldprspSSTLCLRTLVE-HTGRVFRLQFDE--FQIVSSSHDDSILIWDF 598
           ***********99..9************************99999*****98.***********9..99*************97 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MDSDPDDCIF EGDENEEVIG QQRMDSPQHM EIANGSNNDD SSNDEVMDDN LPAAMMMQGV 60
PVSIGIDNHP TASSNVSNSN PMQHQSVTLS ILPASHNIQS LQDRIDVRNT NLDSGPILTN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGGTGTTT TAATTTACTT ATTTTGCTGC ATGATCTGTT GCAAAGCTGG TGGTAACGAA 60
CCGTAGACAA GCTACACATA CCATTATGGA CAGTGACCCT GATGATTGCA TATTTGAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

cin:445628

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001961	Ailuropoda melanoleuca	74.90	0.00e+00	833.00
IUUC-Apl-003437	Anas platyrhynchos	78.20	0.00e+00	829.00
IUUC-Aca-004410	Anolis carolinensis	73.95	0.00e+00	820.00
IUUC-Ago-007794	Ashbya gossypii	29.30	2.00e-46	178.00
IUUC-Acl-008355	Aspergillus clavatus	30.11	3.00e-50	192.00
IUUC-Afl-008580	Aspergillus flavus	29.08	4.00e-44	171.00
IUUC-Afu-008790	Aspergillus fumigatus	29.89	7.00e-47	180.00
IUUC-Ani-009324	Aspergillus nidulans	30.57	1.00e-50	193.00
IUUC-Ang-009766	Aspergillus niger	32.38	1.00e-53	202.00
IUUC-Aor-009916	Aspergillus oryzae	30.09	2.00e-47	182.00
IUUC-Ate-010492	Aspergillus terreus	30.41	8.00e-50	190.00
IUUC-Ame-011393	Astyanax mexicanus	78.11	0.00e+00	799.00
IUUC-Bgr-012194	Blumeria graminis	32.59	2.00e-53	202.00
IUUC-Bta-013453	Bos taurus	74.90	0.00e+00	833.00
IUUC-Bci-013685	Botrytis cinerea	32.24	2.00e-58	218.00
IUUC-Cel-018392	Caenorhabditis elegans	62.55	2.00e-178	617.00
IUUC-Cja-019121	Callithrix jacchus	75.10	0.00e+00	835.00
IUUC-Cfa-020553	Canis familiaris	75.10	0.00e+00	834.00
IUUC-Cpo-022151	Cavia porcellus	80.00	0.00e+00	817.00
IUUC-Csa-023688	Chlorocebus sabaeus	75.10	0.00e+00	835.00
IUUC-Cho-024658	Choloepus hoffmanni	72.45	4.00e-87	313.00
IUUC-Csv-026020	Ciona savignyi	86.58	0.00e+00	1060.00
IUUC-Cgl-026429	Colletotrichum gloeosporioides	35.37	1.00e-63	236.00
IUUC-Cne-027018	Cryptococcus neoformans	26.68	1.00e-42	167.00
IUUC-Cme-027168	Cyanidioschyzon merolae	26.92	2.00e-29	123.00
IUUC-Dre-028322	Danio rerio	78.95	0.00e+00	802.00
IUUC-Dno-029484	Dasypus novemcinctus	71.00	0.00e+00	794.00
IUUC-Dor-030498	Dipodomys ordii	80.00	0.00e+00	819.00
IUUC-Dse-031196	Dothistroma septosporum	32.26	3.00e-49	189.00
IUUC-Dme-031885	Drosophila melanogaster	72.23	0.00e+00	756.00
IUUC-Ete-032978	Echinops telfairi	62.62	0.00e+00	649.00
IUUC-Eca-033804	Equus caballus	80.42	0.00e+00	825.00
IUUC-Eeu-034760	Erinaceus europaeus	67.79	5.00e-141	493.00
IUUC-Fca-035427	Felis catus	75.10	0.00e+00	835.00
IUUC-Fal-037530	Ficedula albicollis	75.29	0.00e+00	835.00
IUUC-Fox-037978	Fusarium oxysporum	34.67	2.00e-63	236.00
IUUC-Fso-038077	Fusarium solani	32.44	5.00e-57	214.00
IUUC-Gmo-038590	Gadus morhua	77.05	0.00e+00	781.00
IUUC-Ggr-039974	Gaeumannomyces graminis	31.49	2.00e-55	209.00
IUUC-Gga-041087	Gallus gallus	75.29	0.00e+00	836.00
IUUC-Gac-041305	Gasterosteus aculeatus	76.84	0.00e+00	785.00
IUUC-Ggo-045369	Gorilla gorilla	75.10	0.00e+00	833.00
IUUC-Hsa-045962	Homo sapiens	75.10	0.00e+00	835.00
IUUC-Itr-047872	Ictidomys tridecemlineatus	78.48	0.00e+00	743.00
IUUC-Lch-050460	Latimeria chalumnae	80.63	0.00e+00	822.00
IUUC-Loc-052686	Lepisosteus oculatus	76.60	0.00e+00	836.00
IUUC-Lma-053289	Leptosphaeria maculans	37.54	1.00e-46	180.00
IUUC-Laf-053968	Loxodonta africana	73.79	0.00e+00	826.00
IUUC-Mcc-055782	Macaca mulatta	75.10	0.00e+00	833.00
IUUC-Meu-056078	Macropus eugenii	69.92	0.00e+00	684.00
IUUC-Mor-057283	Magnaporthe oryzae	32.52	3.00e-57	215.00
IUUC-Mpo-057540	Magnaporthe poae	31.71	2.00e-55	209.00
IUUC-Mla-058989	Melampsora laricipopulina	39.94	7.00e-58	216.00
IUUC-Mga-059388	Meleagris gallopavo	75.29	0.00e+00	837.00
IUUC-Mvi-060284	Microbotryum violaceum	44.82	7.00e-71	260.00
IUUC-Mmr-060969	Microcebus murinus	75.10	0.00e+00	834.00
IUUC-Mdo-063041	Monodelphis domestica	75.48	0.00e+00	817.00
IUUC-Mmu-064096	Mus musculus	75.29	0.00e+00	837.00
IUUC-Mpu-065716	Mustela putorius furo	80.42	0.00e+00	825.00
IUUC-Mlu-067001	Myotis lucifugus	80.42	0.00e+00	825.00
IUUC-Nfi-068263	Neosartorya fischeri	29.63	2.00e-50	192.00
IUUC-Ncr-068736	Neurospora crassa	41.46	3.00e-46	178.00
IUUC-Nle-069548	Nomascus leucogenys	75.10	0.00e+00	835.00
IUUC-Opr-071229	Ochotona princeps	80.42	0.00e+00	823.00
IUUC-Ont-071792	Oreochromis niloticus	77.89	0.00e+00	796.00
IUUC-Oan-072867	Ornithorhynchus anatinus	78.16	0.00e+00	833.00
IUUC-Ocu-074246	Oryctolagus cuniculus	75.10	0.00e+00	834.00
IUUC-Ola-086985	Oryzias latipes	77.47	0.00e+00	795.00
IUUC-Oga-088244	Otolemur garnettii	78.16	0.00e+00	832.00
IUUC-Oar-090412	Ovis aries	73.79	0.00e+00	826.00
IUUC-Ptr-091039	Pan troglodytes	80.42	0.00e+00	825.00
IUUC-Pan-092826	Papio anubis	75.10	0.00e+00	835.00
IUUC-Psi-093887	Pelodiscus sinensis	79.79	0.00e+00	816.00
IUUC-Pma-094315	Petromyzon marinus	76.62	0.00e+00	766.00
IUUC-Pno-094808	Phaeosphaeria nodorum	30.85	4.00e-47	181.00
IUUC-Pfo-096783	Poecilia formosa	77.68	0.00e+00	795.00
IUUC-Pab-097680	Pongo abelii	74.90	0.00e+00	833.00
IUUC-Pca-100843	Procavia capensis	69.92	0.00e+00	740.00
IUUC-Pva-102547	Pteropus vampyrus	80.21	0.00e+00	818.00
IUUC-Pgr-103358	Puccinia graminis	36.92	2.00e-50	191.00
IUUC-Ptt-103853	Puccinia triticina	32.39	1.00e-57	216.00
IUUC-Pte-104392	Pyrenophora teres	37.59	2.00e-46	179.00
IUUC-Pyt-104678	Pyrenophora triticirepentis	37.59	2.00e-46	179.00
IUUC-Rno-105246	Rattus norvegicus	74.07	0.00e+00	827.00
IUUC-Sha-107454	Sarcophilus harrisii	75.29	0.00e+00	817.00
IUUC-Sja-107743	Schizosaccharomyces japonicus	36.67	5.00e-72	263.00
IUUC-Spo-108200	Schizosaccharomyces pombe	31.37	1.00e-61	229.00
IUUC-Sar-113471	Sorex araneus	62.73	1.00e-178	618.00
IUUC-Sre-114916	Sporisorium reilianum	32.67	7.00e-44	171.00
IUUC-Ssc-115490	Sus scrofa	78.16	0.00e+00	831.00
IUUC-Tgu-117445	Taeniopygia guttata	75.10	0.00e+00	835.00
IUUC-Tru-117671	Takifugu rubripes	77.05	0.00e+00	790.00
IUUC-Tsy-118983	Tarsius syrichta	72.61	0.00e+00	795.00
IUUC-Tni-120359	Tetraodon nigroviridis	77.05	0.00e+00	787.00
IUUC-Tre-122207	Trichoderma reesei	34.36	2.00e-58	218.00
IUUC-Tvi-122344	Trichoderma virens	35.68	5.00e-60	224.00
IUUC-Tme-127141	Tuber melanosporum	33.78	6.00e-63	233.00
IUUC-Tbe-127418	Tupaia belangeri	76.00	0.00e+00	764.00
IUUC-Ttr-128946	Tursiops truncatus	74.90	0.00e+00	833.00
IUUC-Uma-129491	Ustilago maydis	33.97	5.00e-45	175.00
IUUC-Vda-129941	Verticillium dahliae	31.94	2.00e-56	212.00
IUUC-Vpa-130668	Vicugna pacos	80.42	0.00e+00	824.00
IUUC-Xtr-132861	Xenopus tropicalis	74.48	0.00e+00	836.00
IUUC-Xma-133187	Xiphophorus maculatus	83.93	2.00e-142	496.00
IUUC-Yli-134582	Yarrowia lipolytica	34.00	2.00e-52	199.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence