iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ola-087063

Ensembl Protein ID

ENSORLP00000013664.1

UniProt Accession

H2M5D9; H2M5D9_ORYLA

Genbank Protein ID

ENSORLP00000013664

Protein Name

Lutropin-choriogonadotropic hormone receptor

Genbank Nucleotide ID

BAAF04029322

Gene Name

LHCGR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000010892.1	ENSORLT00000013665.1	ENSORLP00000013664.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	48.15	2.90e-01	32.00	IUUC-Spo-108080

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryzias latipes

Functional Description
(View)

Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

Protein Sequence
(Fasta)

MAPRAVWLLV ALSGVLNARS CQAYPCHPIC RCTPDTFQCN RDTQLAAGTA EHRLRLTHLP 60
LKQVPTHAFK ELMNITIIEI SQSDRITAIQ RHAFLSLHSL QQILVLNINS LRGIERGAFT 120

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Nucleotide Sequence
(Fasta)

ATGGCTCCCC GGGCGGTCTG GCTCCTGGTC GCGCTGTCCG GTGTCCTGAA CGCGCGCTCC 60
TGCCAGGCGT ACCCCTGTCA TCCCATCTGC CGCTGCACCC CCGACACGTT TCAGTGCAAC 120

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Sequence Source

Ensembl

Keyword

KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0297--G-protein coupled receptor
KW-0433--Leucine-rich repeat
KW-0472--Membrane
KW-0675--Receptor
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0807--Transducer
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR002272--FSH_rcpt
IPR000276--GPCR_Rhodpsn
IPR017452--GPCR_Rhodpsn_7TM
IPR002131--Gphrmn_rcpt_fam
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR026906--LRR_5
IPR002273--LSH_rcpt
IPR034298--TSHR/LHCGR/FSHR

PROSITE

PS00237--G_PROTEIN_RECEP_F1_1
PS50262--G_PROTEIN_RECEP_F1_2

Pfam

PF00001--7tm_1
PF13306--LRR_5
PF13855--LRR_8

PRINTS

PR00373--GLYCHORMONER
PR00237--GPCRRHODOPSN
PR01144--LSHRECEPTOR

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0004963--F:follicle-stimulating hormone receptor activity
GO:0004964--F:luteinizing hormone receptor activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013064	Bos taurus	21.57	1.00e-02	33.90
IUUC-Cho-024336	Choloepus hoffmanni	25.93	2.70e-02	32.30
IUUC-Fox-037866	Fusarium oxysporum	32.14	1.10e+00	28.90
IUUC-Lch-049802	Latimeria chalumnae	24.18	5.00e-07	48.90
IUUC-Loc-052069	Lepisosteus oculatus	24.26	1.00e-03	38.10
IUUC-Mla-058951	Melampsora laricipopulina	33.75	3.50e-01	29.30
IUUC-Mdo-062558	Monodelphis domestica	22.73	6.00e-05	41.60
IUUC-Oan-072894	Ornithorhynchus anatinus	25.33	2.00e-05	43.50
IUUC-Pfo-096201	Poecilia formosa	21.40	1.00e-04	40.40
IUUC-Sha-107148	Sarcophilus harrisii	22.79	1.00e-03	37.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence