iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000020400.17	ENSMUST00000102730.8	ENSMUSP00000099791.2
ENSMUSG00000020400.17	ENSMUST00000018482.12	ENSMUSP00000018482.6

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
miRTarBase	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
iRefIndex
Post-translational Modifications (PTMs)
PHOSIDA	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	1.60e-23	83.5	465	523

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslka 59
           k+el++++e+LkqQv+i++eDFq+ER+dREr+neekeeL++qveklq+qv++ n++lk 
   Q: 465  KQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLTNAQLKT 523
           699*****************************************************996 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MEGRGPYGIY DPGGSTPLGE VSAAFERLVE ENTRLKGKMQ GIKMLGELLE ESQMEASRLR 60
QKAEELVKDS ELSPPTSAPS LVSFDDLAEL TGQDTKVQVH PATSTAATTT ATATTGNSME 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGACACAG GGAGGCATGG CCGCACTCAC TGGGCACATC TTCAGATCAC CTCGTGCATT 60
CTCGGATGAG TGACCTGGGC TGAAGGTAGG TGTGACAAGG CAGATTCCAG GAGCGTCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR033372--TNIP1

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0009101--P:glycoprotein biosynthetic process
GO:0007159--P:leukocyte cell-cell adhesion
GO:0085032--P:modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade
GO:0002755--P:MyD88-dependent toll-like receptor signaling pathway
GO:0070373--P:negative regulation of ERK1 and ERK2 cascade
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050727--P:regulation of inflammatory response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002103	Ailuropoda melanoleuca	81.82	0.00e+00	816.00
IUUC-Apl-004176	Anas platyrhynchos	53.40	6.00e-150	524.00
IUUC-Aca-004362	Anolis carolinensis	55.78	3.00e-141	495.00
IUUC-Ame-011307	Astyanax mexicanus	40.67	1.00e-86	314.00
IUUC-Bta-012620	Bos taurus	79.87	0.00e+00	735.00
IUUC-Cja-018996	Callithrix jacchus	82.13	0.00e+00	895.00
IUUC-Cfa-020274	Canis familiaris	81.64	0.00e+00	815.00
IUUC-Cpo-021786	Cavia porcellus	79.91	0.00e+00	877.00
IUUC-Csa-023236	Chlorocebus sabaeus	81.05	0.00e+00	809.00
IUUC-Cho-024535	Choloepus hoffmanni	69.82	7.00e-50	191.00
IUUC-Cin-025355	Ciona intestinalis	29.03	4.00e-11	63.50
IUUC-Dre-028725	Danio rerio	47.25	1.00e-115	410.00
IUUC-Dno-028967	Dasypus novemcinctus	87.99	9.00e-117	412.00
IUUC-Dor-030761	Dipodomys ordii	75.34	1.00e-100	360.00
IUUC-Ete-032695	Echinops telfairi	68.96	0.00e+00	754.00
IUUC-Eca-033655	Equus caballus	81.35	0.00e+00	885.00
IUUC-Eeu-035335	Erinaceus europaeus	62.16	1.00e-98	354.00
IUUC-Fca-035597	Felis catus	83.33	0.00e+00	879.00
IUUC-Fal-037020	Ficedula albicollis	52.85	1.00e-142	499.00
IUUC-Gga-040812	Gallus gallus	52.89	8.00e-143	500.00
IUUC-Ggo-045345	Gorilla gorilla	80.89	0.00e+00	884.00
IUUC-Hsa-045785	Homo sapiens	82.13	0.00e+00	906.00
IUUC-Itr-048029	Ictidomys tridecemlineatus	80.89	0.00e+00	927.00
IUUC-Lch-049745	Latimeria chalumnae	51.65	2.00e-110	392.00
IUUC-Loc-052635	Lepisosteus oculatus	49.83	7.00e-131	461.00
IUUC-Laf-053625	Loxodonta africana	80.22	0.00e+00	817.00
IUUC-Mcc-055730	Macaca mulatta	81.20	0.00e+00	848.00
IUUC-Meu-056550	Macropus eugenii	69.86	5.00e-112	398.00
IUUC-Mpo-057394	Magnaporthe poae	34.62	1.40e-01	32.30
IUUC-Mtr-058001	Medicago truncatula	48.57	4.10e-01	28.10
IUUC-Mga-059948	Meleagris gallopavo	68.29	3.00e-72	264.00
IUUC-Mmr-060900	Microcebus murinus	81.92	0.00e+00	947.00
IUUC-Mdo-061805	Monodelphis domestica	66.46	0.00e+00	738.00
IUUC-Mpu-065979	Mustela putorius furo	81.04	0.00e+00	906.00
IUUC-Mlu-067100	Myotis lucifugus	78.37	0.00e+00	863.00
IUUC-Nle-069667	Nomascus leucogenys	82.43	0.00e+00	880.00
IUUC-Opr-070478	Ochotona princeps	76.70	0.00e+00	863.00
IUUC-Ont-071777	Oreochromis niloticus	46.34	1.00e-106	380.00
IUUC-Oan-073239	Ornithorhynchus anatinus	65.25	0.00e+00	696.00
IUUC-Ocu-073879	Oryctolagus cuniculus	80.40	0.00e+00	833.00
IUUC-Oga-088900	Otolemur garnettii	83.62	0.00e+00	987.00
IUUC-Oar-089444	Ovis aries	76.34	0.00e+00	770.00
IUUC-Ptr-090641	Pan troglodytes	82.13	0.00e+00	906.00
IUUC-Pan-092283	Papio anubis	81.50	0.00e+00	834.00
IUUC-Psi-092967	Pelodiscus sinensis	51.77	1.00e-144	506.00
IUUC-Pma-094726	Petromyzon marinus	31.42	2.00e-49	190.00
IUUC-Pfo-096085	Poecilia formosa	45.67	8.00e-109	387.00
IUUC-Pab-097976	Pongo abelii	77.90	0.00e+00	846.00
IUUC-Pca-100215	Procavia capensis	71.94	0.00e+00	697.00
IUUC-Pva-102258	Pteropus vampyrus	77.31	0.00e+00	831.00
IUUC-Rno-105833	Rattus norvegicus	92.45	0.00e+00	954.00
IUUC-Sly-111729	Solanum lycopersicum	26.96	8.00e-04	39.70
IUUC-Stu-112653	Solanum tuberosum	28.10	4.00e-04	40.40
IUUC-Sar-113660	Sorex araneus	44.44	5.00e-13	68.60
IUUC-Ssc-115652	Sus scrofa	77.74	0.00e+00	807.00
IUUC-Tgu-116648	Taeniopygia guttata	52.12	5.00e-128	451.00
IUUC-Tru-118455	Takifugu rubripes	48.98	1.00e-106	380.00
IUUC-Tsy-119152	Tarsius syrichta	46.23	5.00e-17	81.60
IUUC-Tbe-128129	Tupaia belangeri	67.61	6.00e-97	348.00
IUUC-Ttr-128305	Tursiops truncatus	73.57	0.00e+00	703.00
IUUC-Vpa-130185	Vicugna pacos	46.43	1.00e-17	83.60
IUUC-Xtr-131842	Xenopus tropicalis	48.49	6.00e-117	414.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence