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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064173
Ensembl Protein ID ENSMUSP00000030427.5
UniProt Accession Q8CB77; Q3UI38; Q80VB2; Q9R0Q5; ELOA1_MOUSE
Genbank Protein ID BAA84994.1; BAC29497.1; BAE26815.1; BAE27668.1; CAM15908.1; EDL29954.1; AAH49885.1
Protein Name Elongin-A; Elongin 110 kDa subunit; RNA polymerase II transcription factor SIII subunit A1; SIII p110; Transcription elongation factor B polypeptide 3
Genbank Nucleotide ID AB025015; AK036592; AK145994; AK147088; AL672076; CH466552; BC049885
Gene Name Tceb3; Eloa
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000028668.5 ENSMUST00000030427.5 ENSMUSP00000030427.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/SCF/F-box 33.82 2.00e-05 46.20 IUUC-Sce-106376
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box 33.82 2.00e-05 46.20 IUUC-Sce-106376
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
 SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
Protein Sequence
(Fasta)
MAAESALQVV EKLQARLAAN PDPKKLLKYL KKLSILPITV DILVETGVGK TVNSFRKHEQ 60
VGNFARDLVA QWKKLVPVER NSEAEDQDFE KNNSRKRPRD ALQREEELEG NYQESWKPSG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064173|E3,F-box;E3,SOCS|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATACACACAC CCCCAGCGGA GGCCCGGAAG GGACCATTCG CGCTTCCGTC TCCGCCGGGC 60
CCTCACGGAG GGCGGAGTTG CGGCCCGAGG ACGCGACGCG AGCCCAGTTC CGGCGAGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064173|E3,F-box;E3,SOCS|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR001810--F-box_dom
IPR010684--RNA_pol_II_trans_fac_SIII_A
IPR003617--TFIIS/CRSP70_N_sub
IPR017923--TFIIS_N
PROSITE

PS50181--FBOX
PS51319--TFIIS_N
Pfam

PF06881--Elongin_A
PF08711--Med26
SMART

SM00509--TFS2N
Gene Ontology

GO:0070449--C:elongin complex
GO:0005615--C:extracellular space
GO:0016021--C:integral component of membrane
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006368--P:transcription elongation from RNA polymerase II promoter
KEGG mmu:27224
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001705 Ailuropoda melanoleuca 79.84 0.00e+00 1044.00
IUUC-Apl-003659 Anas platyrhynchos 76.32 4.00e-130 458.00
IUUC-Aca-004513 Anolis carolinensis 54.71 0.00e+00 666.00
IUUC-Ago-007835 Ashbya gossypii 27.27 9.00e-06 44.30
IUUC-Acl-008085 Aspergillus clavatus 26.72 3.00e-07 49.70
IUUC-Afu-008931 Aspergillus fumigatus 27.59 3.00e-07 49.70
IUUC-Ani-009161 Aspergillus nidulans 23.70 3.00e-08 52.80
IUUC-Ang-009875 Aspergillus niger 26.32 2.00e-05 43.50
IUUC-Ame-011668 Astyanax mexicanus 59.02 1.00e-85 310.00
IUUC-Bta-013219 Bos taurus 74.90 0.00e+00 967.00
IUUC-Bci-014000 Botrytis cinerea 23.29 5.00e-07 48.90
IUUC-Bdi-014527 Brachypodium distachyon 38.03 2.00e-09 56.20
IUUC-Bol-016438 Brassica oleracea 32.26 1.00e-08 54.30
IUUC-Bra-017526 Brassica rapa 32.26 1.00e-08 54.30
IUUC-Cel-018281 Caenorhabditis elegans 31.74 2.00e-15 77.40
IUUC-Cja-018759 Callithrix jacchus 80.08 0.00e+00 1099.00
IUUC-Cfa-020766 Canis familiaris 76.78 0.00e+00 994.00
IUUC-Cpo-022250 Cavia porcellus 79.68 0.00e+00 995.00
IUUC-Csa-023293 Chlorocebus sabaeus 81.11 0.00e+00 1120.00
IUUC-Cin-025556 Ciona intestinalis 38.87 4.00e-48 186.00
IUUC-Csv-026153 Ciona savignyi 40.00 5.00e-39 154.00
IUUC-Cgl-026733 Colletotrichum gloeosporioides 27.08 8.00e-04 38.10
IUUC-Cne-026936 Cryptococcus neoformans 26.47 3.00e-05 43.10
IUUC-Dre-027828 Danio rerio 44.07 4.00e-77 282.00
IUUC-Dse-031436 Dothistroma septosporum 30.95 1.00e-04 41.20
IUUC-Dme-031809 Drosophila melanogaster 32.89 2.00e-40 160.00
IUUC-Ete-032677 Echinops telfairi 87.54 2.00e-147 515.00
IUUC-Eca-034045 Equus caballus 75.77 3.00e-113 402.00
IUUC-Eeu-035063 Erinaceus europaeus 84.13 4.00e-163 568.00
IUUC-Fca-036488 Felis catus 79.44 0.00e+00 1027.00
IUUC-Fal-037501 Ficedula albicollis 55.62 0.00e+00 633.00
IUUC-Fso-038123 Fusarium solani 31.33 2.00e-04 40.00
IUUC-Gmo-038614 Gadus morhua 68.78 2.00e-76 280.00
IUUC-Ggr-039793 Gaeumannomyces graminis 36.25 3.00e-08 52.80
IUUC-Gga-040738 Gallus gallus 56.19 0.00e+00 701.00
IUUC-Gac-041381 Gasterosteus aculeatus 53.47 1.00e-97 350.00
IUUC-Gma-042964 Glycine max 30.88 3.00e-04 38.90
IUUC-Ggo-045139 Gorilla gorilla 80.98 0.00e+00 1113.00
IUUC-Hsa-046083 Homo sapiens 80.98 0.00e+00 1120.00
IUUC-Itr-048970 Ictidomys tridecemlineatus 81.70 0.00e+00 1030.00
IUUC-Kpa-049376 Komagataella pastoris 38.10 1.00e-05 43.50
IUUC-Lch-050369 Latimeria chalumnae 65.06 9.00e-68 251.00
IUUC-Lpe-050727 Leersia perrieri 32.86 8.00e-07 47.80
IUUC-Loc-052347 Lepisosteus oculatus 57.19 1.00e-72 267.00
IUUC-Lma-053027 Leptosphaeria maculans 22.32 3.50e-01 28.90
IUUC-Laf-053575 Loxodonta africana 82.16 0.00e+00 1100.00
IUUC-Mcc-054823 Macaca mulatta 80.03 0.00e+00 1063.00
IUUC-Meu-056878 Macropus eugenii 40.03 1.00e-96 346.00
IUUC-Mor-056948 Magnaporthe oryzae 31.87 5.00e-07 48.90
IUUC-Mtr-057811 Medicago truncatula 25.49 8.00e-04 37.40
IUUC-Mla-058917 Melampsora laricipopulina 36.62 6.00e-11 62.00
IUUC-Mga-059445 Meleagris gallopavo 56.62 0.00e+00 669.00
IUUC-Mmr-060665 Microcebus murinus 78.77 0.00e+00 1059.00
IUUC-Mdo-062430 Monodelphis domestica 63.57 0.00e+00 767.00
IUUC-Mac-065364 Musa acuminata 33.80 1.00e-04 39.70
IUUC-Mpu-066344 Mustela putorius furo 77.58 0.00e+00 992.00
IUUC-Mlu-068101 Myotis lucifugus 80.64 0.00e+00 1078.00
IUUC-Nfi-068489 Neosartorya fischeri 27.59 2.00e-07 50.40
IUUC-Opr-070498 Ochotona princeps 47.49 1.00e-45 177.00
IUUC-Ont-071579 Oreochromis niloticus 53.69 1.00e-87 317.00
IUUC-Oan-072862 Ornithorhynchus anatinus 56.60 0.00e+00 681.00
IUUC-Ocu-073882 Oryctolagus cuniculus 73.04 0.00e+00 831.00
IUUC-Oba-075710 Oryza barthii 35.21 2.00e-07 49.70
IUUC-Ogl-077171 Oryza glaberrima 35.21 2.00e-07 49.30
IUUC-Ogu-078827 Oryza glumaepatula 35.21 4.00e-07 49.30
IUUC-Oin-080204 Oryza indica 35.21 2.00e-07 49.70
IUUC-Olo-081049 Oryza longistaminata 35.21 2.00e-07 49.70
IUUC-Ome-081128 Oryza meridionalis 33.77 1.00e-05 42.70
IUUC-Oni-083077 Oryza nivara 35.21 1.00e-07 50.40
IUUC-Opu-083270 Oryza punctata 33.80 1.00e-06 47.00
IUUC-Oru-084299 Oryza rufipogon 33.77 1.00e-05 42.70
IUUC-Osa-085671 Oryza sativa 33.77 1.00e-06 44.70
IUUC-Ola-086456 Oryzias latipes 61.89 9.00e-92 331.00
IUUC-Oga-087918 Otolemur garnettii 81.48 0.00e+00 1074.00
IUUC-Oar-089663 Ovis aries 75.77 0.00e+00 966.00
IUUC-Ptr-091033 Pan troglodytes 80.19 0.00e+00 1077.00
IUUC-Pan-092277 Papio anubis 80.33 0.00e+00 1119.00
IUUC-Psi-094086 Pelodiscus sinensis 55.38 0.00e+00 687.00
IUUC-Pma-094683 Petromyzon marinus 45.82 1.00e-59 223.00
IUUC-Pno-094930 Phaeosphaeria nodorum 34.38 2.00e-09 56.60
IUUC-Pfo-097334 Poecilia formosa 59.09 4.00e-87 315.00
IUUC-Pab-098345 Pongo abelii 80.87 0.00e+00 1078.00
IUUC-Pop-099683 Populus trichocarpa 31.43 4.00e-04 36.60
IUUC-Pca-100737 Procavia capensis 79.23 0.00e+00 1066.00
IUUC-Pva-102497 Pteropus vampyrus 81.03 0.00e+00 1130.00
IUUC-Pgr-103464 Puccinia graminis 36.62 2.00e-11 61.60
IUUC-Pte-104288 Pyrenophora teres 29.79 3.00e-07 49.30
IUUC-Pyt-104772 Pyrenophora triticirepentis 28.72 6.00e-07 48.10
IUUC-Rno-105177 Rattus norvegicus 92.76 0.00e+00 1196.00
IUUC-Sce-106376 Saccharomyces cerevisiae 31.71 4.00e-07 48.90
IUUC-Sha-106480 Sarcophilus harrisii 66.58 0.00e+00 822.00
IUUC-Sja-107782 Schizosaccharomyces japonicus 27.41 1.00e-12 67.00
IUUC-Spo-108157 Schizosaccharomyces pombe 29.17 8.00e-11 60.10
IUUC-Sit-109960 Setaria italica 25.84 3.00e-04 38.90
IUUC-Sar-113255 Sorex araneus 68.74 0.00e+00 755.00
IUUC-Sbi-114855 Sorghum bicolor 38.03 3.00e-06 45.80
IUUC-Sre-115076 Sporisorium reilianum 37.00 7.00e-17 82.40
IUUC-Ssc-115875 Sus scrofa 79.67 0.00e+00 1070.00
IUUC-Tgu-117066 Taeniopygia guttata 52.49 3.00e-173 602.00
IUUC-Tru-117881 Takifugu rubripes 56.17 9.00e-93 334.00
IUUC-Tsy-119531 Tarsius syrichta 76.45 0.00e+00 1018.00
IUUC-Tni-120325 Tetraodon nigroviridis 39.81 6.00e-118 418.00
IUUC-Tae-122727 Triticum aestivum 30.77 2.00e-09 56.60
IUUC-Tur-126506 Triticum urartu 31.62 4.00e-08 51.60
IUUC-Tbe-127648 Tupaia belangeri 74.83 0.00e+00 947.00
IUUC-Ttr-129287 Tursiops truncatus 78.23 0.00e+00 1026.00
IUUC-Uma-129543 Ustilago maydis 33.64 3.00e-14 73.90
IUUC-Vpa-130645 Vicugna pacos 76.01 0.00e+00 986.00
IUUC-Xtr-132709 Xenopus tropicalis 57.05 2.00e-125 442.00
IUUC-Xma-133858 Xiphophorus maculatus 60.53 3.00e-88 319.00
IUUC-Yli-134386 Yarrowia lipolytica 32.14 5.00e-09 55.10
IUUC-Zma-135412 Zea mays 29.47 4.00e-06 45.10
Created Date 25-Jun-2017

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