iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088912

Ensembl Protein ID

ENSOGAP00000021409.1

UniProt Accession

H0XZ66; H0XZ66_OTOGA

Genbank Protein ID

ENSOGAP00000021409

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03060298

Gene Name

RNF5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000031466.1	ENSOGAT00000029246.1	ENSOGAP00000021409.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-07	31.1	27	68

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iCle  ++  +v  CgH+++  Cl++w         ++ CP+C+
   Q: 27   CNICLETARE-AVVSVCGHLYCWPCLHQW---LETRPERQECPVCK 68
           99******88.888***************...555888889****7 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAAAEEEDGG PEGPNRERGG AGATFECNIC LETAREAVVS VCGHLYCWPC LHQWLETRPE 60
RQECPVCKAG ISREKVVPLY GRGSQKPQDP RLKTPPRPQG QRPAPESRGG FQPFGDTGGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTACTTGGG GGGCTAAACA AACCCGGCCA TGGCAGCAGC AGAGGAGGAG GATGGGGGCC 60
CCGAAGGGCC AAACCGCGAG CGGGGCGGGG CGGGCGCGAC CTTCGAATGT AATATATGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0010507--P:negative regulation of autophagy
GO:0031648--P:protein destabilization
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:2000785--P:regulation of autophagosome assembly
GO:0009617--P:response to bacterium

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001417	Ailuropoda melanoleuca	99.21	2.00e-71	261.00
IUUC-Aca-004254	Anolis carolinensis	75.86	4.00e-36	143.00
IUUC-Ame-011316	Astyanax mexicanus	70.78	1.00e-57	215.00
IUUC-Bta-013109	Bos taurus	99.29	4.00e-80	290.00
IUUC-Bdi-014313	Brachypodium distachyon	54.65	1.00e-23	103.00
IUUC-Cja-019902	Callithrix jacchus	98.58	4.00e-79	286.00
IUUC-Cfa-020079	Canis familiaris	98.58	2.00e-79	287.00
IUUC-Cpo-021320	Cavia porcellus	92.81	5.00e-87	312.00
IUUC-Csa-023595	Chlorocebus sabaeus	98.58	9.00e-80	288.00
IUUC-Dre-027716	Danio rerio	74.29	2.00e-42	165.00
IUUC-Dno-029843	Dasypus novemcinctus	86.52	2.00e-56	211.00
IUUC-Dor-030170	Dipodomys ordii	98.39	2.00e-69	254.00
IUUC-Eca-033642	Equus caballus	99.39	6.00e-93	332.00
IUUC-Eeu-034778	Erinaceus europaeus	99.15	2.00e-64	237.00
IUUC-Fca-036326	Felis catus	97.16	5.00e-79	286.00
IUUC-Fso-038195	Fusarium solani	40.91	3.00e-10	59.70
IUUC-Gac-042258	Gasterosteus aculeatus	80.00	6.00e-56	209.00
IUUC-Ggo-045474	Gorilla gorilla	99.29	5.00e-80	289.00
IUUC-Hsa-046046	Homo sapiens	99.29	5.00e-80	289.00
IUUC-Hvu-047124	Hordeum vulgare	54.65	2.00e-23	102.00
IUUC-Itr-048037	Ictidomys tridecemlineatus	98.00	2.00e-84	303.00
IUUC-Lch-050367	Latimeria chalumnae	71.67	3.00e-46	176.00
IUUC-Lpe-051034	Leersia perrieri	45.26	1.00e-25	109.00
IUUC-Laf-053395	Loxodonta africana	97.16	2.00e-78	284.00
IUUC-Mcc-054833	Macaca mulatta	98.58	9.00e-80	288.00
IUUC-Meu-055984	Macropus eugenii	86.08	5.00e-36	143.00
IUUC-Mdo-062437	Monodelphis domestica	87.80	1.00e-82	298.00
IUUC-Mmu-064159	Mus musculus	97.18	1.00e-79	288.00
IUUC-Mlu-067689	Myotis lucifugus	91.98	2.00e-83	301.00
IUUC-Nle-069705	Nomascus leucogenys	99.29	5.00e-80	289.00
IUUC-Opr-070392	Ochotona princeps	43.97	3.00e-20	90.90
IUUC-Ont-072482	Oreochromis niloticus	74.13	2.00e-58	218.00
IUUC-Ocu-074208	Oryctolagus cuniculus	97.87	9.00e-79	285.00
IUUC-Oba-075461	Oryza barthii	52.75	3.00e-24	105.00
IUUC-Obr-076382	Oryza brachyantha	56.98	7.00e-25	107.00
IUUC-Olo-080378	Oryza longistaminata	54.65	1.00e-23	102.00
IUUC-Opu-083362	Oryza punctata	58.14	1.00e-25	110.00
IUUC-Oru-084757	Oryza rufipogon	55.00	8.00e-27	113.00
IUUC-Osa-086198	Oryza sativa	50.44	8.00e-27	114.00
IUUC-Ola-086507	Oryzias latipes	68.48	8.00e-61	226.00
IUUC-Oar-090284	Ovis aries	95.97	6.00e-72	263.00
IUUC-Ptr-090919	Pan troglodytes	99.21	1.00e-70	258.00
IUUC-Pan-092843	Papio anubis	98.58	9.00e-80	288.00
IUUC-Pfo-096818	Poecilia formosa	79.37	1.00e-56	212.00
IUUC-Pab-098244	Pongo abelii	98.58	1.00e-79	288.00
IUUC-Pca-100319	Procavia capensis	97.56	8.00e-83	298.00
IUUC-Pva-102249	Pteropus vampyrus	94.33	2.00e-73	267.00
IUUC-Rno-106042	Rattus norvegicus	97.18	1.00e-79	288.00
IUUC-Smo-109079	Selaginella moellendorffii	48.19	2.00e-22	100.00
IUUC-Sit-110690	Setaria italica	53.57	3.00e-22	98.20
IUUC-Sly-110917	Solanum lycopersicum	52.94	4.00e-25	107.00
IUUC-Sbi-114275	Sorghum bicolor	54.65	2.00e-23	102.00
IUUC-Ssc-115934	Sus scrofa	100.00	1.00e-80	291.00
IUUC-Tru-118679	Takifugu rubripes	61.73	3.00e-23	100.00
IUUC-Tsy-119615	Tarsius syrichta	95.77	1.00e-75	274.00
IUUC-Tae-124655	Triticum aestivum	54.65	1.00e-23	102.00
IUUC-Tur-126443	Triticum urartu	54.02	2.00e-23	102.00
IUUC-Tbe-127773	Tupaia belangeri	97.16	8.00e-77	279.00
IUUC-Ttr-128690	Tursiops truncatus	98.29	3.00e-64	237.00
IUUC-Vvi-131225	Vitis vinifera	60.00	6.00e-26	110.00
IUUC-Xtr-132608	Xenopus tropicalis	80.83	7.00e-46	176.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence