iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041295

UUCD1 version

UUC-GaA-00333

Ensembl Protein ID

ENSGACP00000009304.1

UniProt Accession

G3NVD5; G3NVD5_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000007003.1	ENSGACT00000009315.1	ENSGACP00000009295.1
ENSGACG00000007003.1	ENSGACT00000009324.1	ENSGACP00000009304.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.80e-128	428.0	410	742

Active Site

Position(s)	Description	Evidence
711	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dl krl+v+f+gEegld+gGv+re+l+lls+e+ np++glf+ys +d +tlq+npds + npehl++F+f+Gr++g+a+++g+++d 
   Q: 410  PKDLWKRLMVKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAV-NPEHLSYFHFVGRIMGMAVFHGHYIDG 497
           678999*****************************************************98.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            ++ +fyk+llgk+++l+d+e+vdp+l++sl +i++n   di+   ld tf+v+++ +ge+ ++eLkp+G++ipV ++ k+eYv+l+v+
   Q: 498  GFTLPFYKQLLGKPITLDDMESVDPDLHNSLVWILDN---DITGV-LDHTFCVEHNAYGEIIQHELKPNGKSIPVSQDTKKEYVRLYVN 582
           ***********************************99...9***8.******************************************* PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +gi+ q+ a+++Gfnevip++ll++F+e+elel++cG  +id++d+k++t+ k+ +t++s+ ++wFw+++e+f++e r+++LqFv
   Q: 583  WRFLRGIEAQFLALQKGFNEVIPQHLLKAFDEKELELIVCGLGKIDIHDWKSNTRLKH-CTAESNIVKWFWKAVESFDEERRARLLQFV 670
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tgssr+Pl+Gf++l+    prlf+i++ das+++lP+++TCfn++++P+Y+ +++l++kLl+Aieet gF +
   Q: 671  TGSSRVPLQGFKALQgaagPRLFTIHQiDASPNNLPKAHTCFNRIDIPPYEHYDKLYDKLLTAIEETCGFAV 742
           **********************************************************************76 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

LSLSFSVLCA KNLVKKDFFR LPDPFAKVVV DGSGQCHSTD TVRNTLDPKW NQHYDLYIGK 60
SDSITISVWN HKKIHKKQGA GFLGCVRLLS NAINRLKDTG YQRLDLNKLS PNDSDTVRGQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATGTTAAAT TAACACTAAA CTATTTCTTT CTTTCTCTCT CTTTTTCAGT CCTGTGTGCC 60
AAAAACCTGG TGAAGAAGGA CTTCTTCCGT AAGTATCTGA AAGTCACAAC GGTTAATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001305	Ailuropoda melanoleuca	91.91	0.00e+00	1403.00
IUUC-Apl-003513	Anas platyrhynchos	92.42	0.00e+00	1420.00
IUUC-Bta-013399	Bos taurus	91.73	0.00e+00	1393.00
IUUC-Cja-019355	Callithrix jacchus	91.78	0.00e+00	1399.00
IUUC-Cpo-022200	Cavia porcellus	92.16	0.00e+00	1403.00
IUUC-Cin-025126	Ciona intestinalis	65.04	0.00e+00	965.00
IUUC-Csv-026339	Ciona savignyi	64.07	0.00e+00	998.00
IUUC-Dre-027650	Danio rerio	92.24	0.00e+00	1446.00
IUUC-Dno-029534	Dasypus novemcinctus	91.40	0.00e+00	1399.00
IUUC-Ete-032715	Echinops telfairi	87.65	0.00e+00	1311.00
IUUC-Eca-033580	Equus caballus	91.89	0.00e+00	1399.00
IUUC-Eeu-034945	Erinaceus europaeus	90.48	0.00e+00	1298.00
IUUC-Fal-037275	Ficedula albicollis	91.83	0.00e+00	1423.00
IUUC-Gmo-039234	Gadus morhua	90.11	0.00e+00	789.00
IUUC-Gga-041060	Gallus gallus	88.49	0.00e+00	1340.00
IUUC-Hsa-046726	Homo sapiens	91.67	0.00e+00	1399.00
IUUC-Lch-050026	Latimeria chalumnae	91.71	0.00e+00	1404.00
IUUC-Loc-051760	Lepisosteus oculatus	88.89	0.00e+00	1400.00
IUUC-Laf-053753	Loxodonta africana	92.15	0.00e+00	1399.00
IUUC-Mcc-054815	Macaca mulatta	91.53	0.00e+00	1396.00
IUUC-Meu-056436	Macropus eugenii	70.43	0.00e+00	1021.00
IUUC-Mmr-060806	Microcebus murinus	92.14	0.00e+00	1399.00
IUUC-Mdo-062805	Monodelphis domestica	90.86	0.00e+00	1386.00
IUUC-Mmu-064034	Mus musculus	91.26	0.00e+00	1395.00
IUUC-Mpu-066762	Mustela putorius furo	91.91	0.00e+00	1406.00
IUUC-Mlu-066981	Myotis lucifugus	91.88	0.00e+00	1398.00
IUUC-Nle-069804	Nomascus leucogenys	91.67	0.00e+00	1401.00
IUUC-Opr-070591	Ochotona princeps	87.11	0.00e+00	1299.00
IUUC-Ont-071239	Oreochromis niloticus	96.90	0.00e+00	1506.00
IUUC-Ocu-074913	Oryctolagus cuniculus	91.53	0.00e+00	1400.00
IUUC-Ola-086597	Oryzias latipes	89.96	0.00e+00	1377.00
IUUC-Oga-089116	Otolemur garnettii	88.77	0.00e+00	1341.00
IUUC-Oar-089366	Ovis aries	91.62	0.00e+00	1395.00
IUUC-Ptr-091382	Pan troglodytes	91.67	0.00e+00	1399.00
IUUC-Psi-093298	Pelodiscus sinensis	92.83	0.00e+00	1399.00
IUUC-Pma-094354	Petromyzon marinus	73.77	0.00e+00	1112.00
IUUC-Pfo-096071	Poecilia formosa	94.07	0.00e+00	1484.00
IUUC-Pab-098682	Pongo abelii	91.67	0.00e+00	1400.00
IUUC-Pva-102754	Pteropus vampyrus	90.91	0.00e+00	1362.00
IUUC-Rno-105600	Rattus norvegicus	91.14	0.00e+00	1201.00
IUUC-Sha-107144	Sarcophilus harrisii	90.99	0.00e+00	1279.00
IUUC-Spo-108171	Schizosaccharomyces pombe	39.85	1.00e-161	563.00
IUUC-Sar-113122	Sorex araneus	81.41	0.00e+00	1187.00
IUUC-Tgu-117112	Taeniopygia guttata	91.43	0.00e+00	1405.00
IUUC-Tbe-127371	Tupaia belangeri	82.65	0.00e+00	1120.00
IUUC-Ttr-129305	Tursiops truncatus	85.65	0.00e+00	1204.00
IUUC-Vpa-130591	Vicugna pacos	82.63	0.00e+00	1209.00
IUUC-Xtr-132979	Xenopus tropicalis	75.00	0.00e+00	1075.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence