iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-054909

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03023912

Gene Name

KLHL40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000021244.3	ENSMMUT00000029892.3	ENSMMUP00000027974.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.70e-14	53.6	34	97
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.10e-07	31.1	130	160

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           D+++  g++ef++h++vLaa+S++F+a fl e e     ++ ++++v+p+v+ ++l++lYt+++ ++
   Q: 34   DCVVRAGEREFPCHRLVLAACSPYFRARFLAEPERA---GELHLEEVSPDVVAQVLHYLYTSEIALD 97
           99999************************9988864...69*********************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           l+Ncl+++r++ l+dc +L+ aa+dfi+ hF
   Q: 130  LSNCLAVFRLGLLLDCARLAVAARDFICAHF 160
           69***************************** PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MALGLEQAEE QRLYQQTLLQ DGLKDMLDHG KFLDCVVRAG EREFPCHRLV LAACSPYFRA 60
RFLAEPERAG ELHLEEVSPD VVAQVLHYLY TSEIALDEAS VQDLFAAAHR FQIPSIFTIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TACAGGGACC CGGCCACCTC TATATATAGC CCCTAGAAGA CAGCTGCGCA GTCTAAGCAA 60
GCCGCAGCAG GAAAGCAGGG GTACAGAGAG GAGCCCCCTT GGCACCGCCA CCACACCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030607--KLHL40
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031397--P:negative regulation of protein ubiquitination
GO:0048741--P:skeletal muscle fiber development

KEGG

mcc:717366

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001792	Ailuropoda melanoleuca	86.54	0.00e+00	1064.00
IUUC-Apl-003748	Anas platyrhynchos	71.11	0.00e+00	905.00
IUUC-Aca-005275	Anolis carolinensis	64.60	0.00e+00	820.00
IUUC-Acl-008133	Aspergillus clavatus	33.87	4.00e-04	40.00
IUUC-Ame-011294	Astyanax mexicanus	56.41	0.00e+00	712.00
IUUC-Bta-012801	Bos taurus	91.51	0.00e+00	1146.00
IUUC-Cja-019795	Callithrix jacchus	95.56	0.00e+00	1045.00
IUUC-Cfa-021245	Canis familiaris	90.13	0.00e+00	798.00
IUUC-Cpo-022436	Cavia porcellus	89.37	0.00e+00	1137.00
IUUC-Csa-023105	Chlorocebus sabaeus	99.36	0.00e+00	1190.00
IUUC-Dre-028603	Danio rerio	57.95	0.00e+00	749.00
IUUC-Dno-030015	Dasypus novemcinctus	72.45	0.00e+00	763.00
IUUC-Dse-031465	Dothistroma septosporum	28.41	2.00e-04	40.00
IUUC-Eca-034393	Equus caballus	93.61	0.00e+00	1066.00
IUUC-Fca-035823	Felis catus	80.16	0.00e+00	984.00
IUUC-Fal-037632	Ficedula albicollis	71.59	0.00e+00	884.00
IUUC-Gmo-039697	Gadus morhua	56.80	0.00e+00	735.00
IUUC-Gga-040525	Gallus gallus	71.43	0.00e+00	907.00
IUUC-Gac-042421	Gasterosteus aculeatus	59.46	0.00e+00	759.00
IUUC-Ggo-045596	Gorilla gorilla	98.71	0.00e+00	1186.00
IUUC-Hsa-046235	Homo sapiens	98.55	0.00e+00	1181.00
IUUC-Itr-048612	Ictidomys tridecemlineatus	93.58	0.00e+00	1170.00
IUUC-Lch-050123	Latimeria chalumnae	66.18	0.00e+00	865.00
IUUC-Loc-051824	Lepisosteus oculatus	63.13	0.00e+00	819.00
IUUC-Laf-053485	Loxodonta africana	89.05	0.00e+00	729.00
IUUC-Meu-055972	Macropus eugenii	75.64	0.00e+00	966.00
IUUC-Mga-059451	Meleagris gallopavo	71.27	0.00e+00	910.00
IUUC-Mmr-060736	Microcebus murinus	94.36	0.00e+00	1176.00
IUUC-Mdo-062563	Monodelphis domestica	76.58	0.00e+00	749.00
IUUC-Mmu-063549	Mus musculus	91.17	0.00e+00	1140.00
IUUC-Mpu-066262	Mustela putorius furo	91.99	0.00e+00	1157.00
IUUC-Mlu-067210	Myotis lucifugus	91.17	0.00e+00	1142.00
IUUC-Nle-069300	Nomascus leucogenys	98.86	0.00e+00	828.00
IUUC-Opr-070384	Ochotona princeps	87.82	0.00e+00	1036.00
IUUC-Ont-071273	Oreochromis niloticus	59.13	0.00e+00	749.00
IUUC-Ocu-074499	Oryctolagus cuniculus	91.55	0.00e+00	1135.00
IUUC-Ola-087175	Oryzias latipes	58.16	0.00e+00	744.00
IUUC-Oga-088855	Otolemur garnettii	93.88	0.00e+00	1165.00
IUUC-Oar-089342	Ovis aries	78.69	0.00e+00	913.00
IUUC-Ptr-091028	Pan troglodytes	98.86	0.00e+00	827.00
IUUC-Pan-091827	Papio anubis	99.68	0.00e+00	1190.00
IUUC-Psi-092998	Pelodiscus sinensis	72.07	0.00e+00	914.00
IUUC-Pma-094586	Petromyzon marinus	57.30	9.00e-96	342.00
IUUC-Pfo-096216	Poecilia formosa	58.24	0.00e+00	759.00
IUUC-Pab-097656	Pongo abelii	98.45	0.00e+00	723.00
IUUC-Pva-102331	Pteropus vampyrus	83.01	0.00e+00	1018.00
IUUC-Rno-105613	Rattus norvegicus	89.48	0.00e+00	1003.00
IUUC-Sha-107091	Sarcophilus harrisii	76.85	0.00e+00	1004.00
IUUC-Sar-112941	Sorex araneus	86.70	0.00e+00	783.00
IUUC-Ssc-116276	Sus scrofa	92.15	0.00e+00	1157.00
IUUC-Tgu-116494	Taeniopygia guttata	71.27	0.00e+00	912.00
IUUC-Tru-118614	Takifugu rubripes	59.29	0.00e+00	767.00
IUUC-Tsy-119499	Tarsius syrichta	93.95	0.00e+00	667.00
IUUC-Tni-119776	Tetraodon nigroviridis	59.13	0.00e+00	760.00
IUUC-Tbe-127806	Tupaia belangeri	84.89	0.00e+00	1037.00
IUUC-Ttr-128813	Tursiops truncatus	91.17	0.00e+00	1143.00
IUUC-Vpa-130127	Vicugna pacos	94.82	0.00e+00	699.00
IUUC-Xtr-132942	Xenopus tropicalis	67.20	0.00e+00	860.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence