iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073243

Ensembl Protein ID

ENSOANP00000030158.1

UniProt Accession

K7E9F1; K7E9F1_ORNAN

Protein Name

Uncharacterized protein

Gene Name

LOC103167900

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000029258.1	ENSOANT00000039401.1	ENSOANP00000030158.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.30e-09	37.4	24	65
E3 activity/RING/U-box	3.30e-06	27.3	20	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCle +++ p+++ C H+f++ C+ k+    +++++  +CPlC+
   Q: 24   CPICLELIRE-PVSTKCDHIFCKFCILKL---LRKKKGPSQCPLCK 65
           ********88.***************777...4669*********7 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk..tcPvtrqplteedlv 56
           + + CpI lel r+Pv +++ + + + +I k l++++   +cP++++ +t ++l 
   Q: 20   KNLECPICLELIREPVSTKCDHIFCKFCILKLLRKKKGpsQCPLCKHDVTRRSLQ 74
           6789***************************995555456*********999985 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MDLPAGEVQE VQGVLADMQK NLECPICLEL IREPVSTKCD HIFCKFCILK LLRKKKGPSQ 60
CPLCKHDVTR RSLQESPRSN KLVEGCGTPS VPSNATRASG FLAARSRAAV PLLSTQRKTW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGCATTTT GTGGTGCTTA GTAACTGATT CTGACTTCTT TTTTCAGGTG TGTGTGCGCG 60
TCCGTCCTTG GGATCGTGTG TCTCTGTGAA TGTTGGAGGC CTAGTTGAAG AGAGAAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011364--BRCA1
IPR031099--BRCA1-associated
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00097--zf-C3HC4

SMART

SM00184--RING

Gene Ontology

GO:0070531--C:BRCA1-A complex
GO:0031436--C:BRCA1-BARD1 complex
GO:0005886--C:plasma membrane
GO:0003677--F:DNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043009--P:chordate embryonic development
GO:0009048--P:dosage compensation by inactivation of X chromosome
GO:0000724--P:double-strand break repair via homologous recombination
GO:0045717--P:negative regulation of fatty acid biosynthetic process
GO:0035067--P:negative regulation of histone acetylation
GO:0071158--P:positive regulation of cell cycle arrest
GO:0035066--P:positive regulation of histone acetylation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042127--P:regulation of cell proliferation

KEGG

oaa:103167900

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002388	Ailuropoda melanoleuca	75.61	2.00e-32	135.00
IUUC-Apl-003252	Anas platyrhynchos	65.12	1.00e-27	119.00
IUUC-Ath-006986	Arabidopsis thaliana	37.93	3.00e-10	60.10
IUUC-Ame-011720	Astyanax mexicanus	52.38	9.00e-21	95.90
IUUC-Bta-013433	Bos taurus	77.38	3.00e-34	141.00
IUUC-Bol-016476	Brassica oleracea	37.93	4.00e-10	59.70
IUUC-Bra-017176	Brassica rapa	35.19	2.00e-10	60.50
IUUC-Cja-019149	Callithrix jacchus	77.38	4.00e-34	140.00
IUUC-Cfa-020322	Canis familiaris	76.19	1.00e-33	139.00
IUUC-Cpo-021583	Cavia porcellus	72.62	1.00e-28	122.00
IUUC-Cre-022597	Chlamydomonas reinhardtii	36.11	9.00e-09	53.90
IUUC-Csa-024227	Chlorocebus sabaeus	76.19	2.00e-34	139.00
IUUC-Cho-024530	Choloepus hoffmanni	75.44	2.00e-21	98.60
IUUC-Cin-025364	Ciona intestinalis	49.21	1.00e-11	63.20
IUUC-Ete-032472	Echinops telfairi	77.19	2.00e-21	98.60
IUUC-Eca-033446	Equus caballus	76.19	1.00e-33	139.00
IUUC-Fca-035991	Felis catus	76.19	7.00e-34	139.00
IUUC-Fal-036803	Ficedula albicollis	59.30	1.00e-26	115.00
IUUC-Gmo-038782	Gadus morhua	53.16	3.00e-18	87.40
IUUC-Gga-040969	Gallus gallus	63.95	1.00e-28	122.00
IUUC-Gac-042296	Gasterosteus aculeatus	53.25	7.00e-19	89.70
IUUC-Gma-044372	Glycine max	38.64	7.00e-10	59.70
IUUC-Ggo-044740	Gorilla gorilla	76.19	2.00e-33	138.00
IUUC-Hsa-046086	Homo sapiens	76.19	2.00e-33	138.00
IUUC-Itr-048512	Ictidomys tridecemlineatus	59.52	2.00e-21	98.60
IUUC-Lch-049789	Latimeria chalumnae	65.12	2.00e-27	118.00
IUUC-Loc-051952	Lepisosteus oculatus	53.49	9.00e-22	99.40
IUUC-Laf-053648	Loxodonta africana	72.62	1.00e-32	135.00
IUUC-Mcc-055210	Macaca mulatta	75.00	2.00e-33	138.00
IUUC-Meu-056342	Macropus eugenii	44.71	8.00e-12	66.60
IUUC-Mtr-058400	Medicago truncatula	39.33	3.00e-11	63.90
IUUC-Mga-060163	Meleagris gallopavo	65.82	3.00e-27	117.00
IUUC-Mdo-062209	Monodelphis domestica	72.94	4.00e-33	137.00
IUUC-Mmu-064003	Mus musculus	73.81	3.00e-32	134.00
IUUC-Mpu-065825	Mustela putorius furo	76.19	2.00e-34	140.00
IUUC-Mlu-068176	Myotis lucifugus	77.50	4.00e-32	134.00
IUUC-Nle-069178	Nomascus leucogenys	76.19	1.00e-33	139.00
IUUC-Opr-070574	Ochotona princeps	51.19	3.00e-17	84.30
IUUC-Ont-072380	Oreochromis niloticus	55.84	1.00e-19	91.70
IUUC-Ocu-074424	Oryctolagus cuniculus	76.19	3.00e-33	137.00
IUUC-Ola-086863	Oryzias latipes	55.84	3.00e-19	90.50
IUUC-Oar-089938	Ovis aries	77.38	3.00e-34	140.00
IUUC-Ptr-090960	Pan troglodytes	76.19	2.00e-33	138.00
IUUC-Pan-092609	Papio anubis	72.97	5.00e-10	60.50
IUUC-Pfo-096328	Poecilia formosa	53.25	5.00e-18	86.70
IUUC-Pab-097982	Pongo abelii	76.19	1.00e-33	139.00
IUUC-Pop-099956	Populus trichocarpa	39.08	1.00e-10	61.60
IUUC-Pca-100698	Procavia capensis	78.95	2.00e-22	101.00
IUUC-Pva-102631	Pteropus vampyrus	77.38	1.00e-33	139.00
IUUC-Rno-105879	Rattus norvegicus	75.00	3.00e-32	134.00
IUUC-Spo-108335	Schizosaccharomyces pombe	39.22	5.00e-08	52.00
IUUC-Sar-113047	Sorex araneus	78.95	3.00e-22	101.00
IUUC-Ssc-115846	Sus scrofa	74.39	3.00e-32	134.00
IUUC-Tgu-116785	Taeniopygia guttata	59.30	2.00e-26	115.00
IUUC-Tru-117895	Takifugu rubripes	40.57	1.00e-18	88.60
IUUC-Tsy-118885	Tarsius syrichta	80.70	2.00e-22	101.00
IUUC-Ttr-128685	Tursiops truncatus	78.95	3.00e-22	101.00
IUUC-Vpa-130216	Vicugna pacos	75.00	1.00e-33	138.00
IUUC-Xtr-132398	Xenopus tropicalis	55.14	5.00e-26	113.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence