iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068023

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02018271

Gene Name

RC3H1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000011127.2	ENSMLUT00000011161.2	ENSMLUP00000010173.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	44.68	3.00e-04	45.10	IUUC-Ath-007510
E3 activity/RING/RING	95.59	0.00e+00	1954.00	IUUC-Hsa-046163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MPVQAPQWTD FLSCPICTQT FDETIRKPIS LGCGHTVCKM CLNKLHRKAC PFDQTTINTD 60
IELLPVNSAL LQLVGAQVPE QQPVTLCSGV EDTKHYDEAR KCVEELALYL KPLSSARGVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTGTAC AAGCTCCACA GTGGACGGAT TTCCTTTCCT GCCCGATTTG CACTCAGACT 60
TTCGACGAAA CAATTCGAAA GCCCATCAGT TTGGGTTGTG GCCATACTGT CTGCAAGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032671--RC3H1
IPR027370--Znf-RING_LisH
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00642--zf-CCCH
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0000932--C:P-body
GO:0003730--F:mRNA 3'-UTR binding
GO:0035613--F:RNA stem-loop binding
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0001782--P:B cell homeostasis
GO:0071347--P:cellular response to interleukin-1
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048535--P:lymph node development
GO:0046007--P:negative regulation of activated T cell proliferation
GO:0030889--P:negative regulation of B cell proliferation
GO:0002635--P:negative regulation of germinal center formation
GO:0045623--P:negative regulation of T-helper cell differentiation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0048536--P:spleen development
GO:0043029--P:T cell homeostasis
GO:0042098--P:T cell proliferation
GO:0061470--P:T follicular helper cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001700	Ailuropoda melanoleuca	95.67	0.00e+00	1932.00
IUUC-Apl-003290	Anas platyrhynchos	85.58	0.00e+00	1815.00
IUUC-Aca-004905	Anolis carolinensis	83.38	0.00e+00	1688.00
IUUC-Aly-006116	Arabidopsis lyrata	44.68	4.00e-06	45.10
IUUC-Ath-007510	Arabidopsis thaliana	44.68	4.00e-06	45.10
IUUC-Ame-011475	Astyanax mexicanus	77.81	0.00e+00	918.00
IUUC-Cja-019907	Callithrix jacchus	95.06	0.00e+00	1959.00
IUUC-Cfa-020679	Canis familiaris	95.49	0.00e+00	1927.00
IUUC-Cpo-022110	Cavia porcellus	90.66	0.00e+00	1907.00
IUUC-Csa-024166	Chlorocebus sabaeus	95.40	0.00e+00	1890.00
IUUC-Dno-029870	Dasypus novemcinctus	92.77	0.00e+00	948.00
IUUC-Dor-030934	Dipodomys ordii	85.92	0.00e+00	1457.00
IUUC-Dme-031708	Drosophila melanogaster	64.51	2.00e-162	566.00
IUUC-Ete-032652	Echinops telfairi	93.53	0.00e+00	1351.00
IUUC-Eca-033236	Equus caballus	94.70	0.00e+00	1889.00
IUUC-Eeu-035091	Erinaceus europaeus	81.82	0.00e+00	867.00
IUUC-Fca-035773	Felis catus	95.41	0.00e+00	1925.00
IUUC-Fal-036972	Ficedula albicollis	84.41	0.00e+00	1793.00
IUUC-Gmo-039303	Gadus morhua	80.94	0.00e+00	894.00
IUUC-Ggo-044691	Gorilla gorilla	89.64	0.00e+00	1806.00
IUUC-Hsa-046163	Homo sapiens	95.59	0.00e+00	1968.00
IUUC-Itr-048266	Ictidomys tridecemlineatus	92.41	0.00e+00	1039.00
IUUC-Lch-050667	Latimeria chalumnae	75.04	0.00e+00	1536.00
IUUC-Loc-052404	Lepisosteus oculatus	68.12	0.00e+00	1310.00
IUUC-Laf-053618	Loxodonta africana	95.17	0.00e+00	1873.00
IUUC-Mcc-054692	Macaca mulatta	95.50	0.00e+00	1972.00
IUUC-Meu-056025	Macropus eugenii	83.31	0.00e+00	910.00
IUUC-Mmr-061188	Microcebus murinus	95.49	0.00e+00	1932.00
IUUC-Mdo-063035	Monodelphis domestica	90.83	0.00e+00	1866.00
IUUC-Mmu-064146	Mus musculus	91.51	0.00e+00	1895.00
IUUC-Mpu-066217	Mustela putorius furo	94.69	0.00e+00	1919.00
IUUC-Nle-069506	Nomascus leucogenys	95.59	0.00e+00	1974.00
IUUC-Opr-070587	Ochotona princeps	82.74	0.00e+00	1586.00
IUUC-Ont-071278	Oreochromis niloticus	78.35	0.00e+00	893.00
IUUC-Oan-073500	Ornithorhynchus anatinus	90.13	0.00e+00	1910.00
IUUC-Ocu-074299	Oryctolagus cuniculus	94.71	0.00e+00	1817.00
IUUC-Ola-086665	Oryzias latipes	78.96	0.00e+00	904.00
IUUC-Oga-088519	Otolemur garnettii	88.45	0.00e+00	1724.00
IUUC-Oar-089246	Ovis aries	94.04	0.00e+00	1810.00
IUUC-Ptr-091102	Pan troglodytes	95.68	0.00e+00	1972.00
IUUC-Pan-091952	Papio anubis	95.51	0.00e+00	1971.00
IUUC-Pfo-097227	Poecilia formosa	61.57	0.00e+00	1161.00
IUUC-Pab-097975	Pongo abelii	92.32	0.00e+00	1880.00
IUUC-Pca-101127	Procavia capensis	89.47	0.00e+00	1283.00
IUUC-Pva-102431	Pteropus vampyrus	87.19	0.00e+00	1723.00
IUUC-Sha-106690	Sarcophilus harrisii	90.22	0.00e+00	1852.00
IUUC-Sbi-114208	Sorghum bicolor	41.30	2.00e-05	43.10
IUUC-Ssc-116189	Sus scrofa	94.70	0.00e+00	1875.00
IUUC-Tgu-116527	Taeniopygia guttata	85.31	0.00e+00	1805.00
IUUC-Tru-118389	Takifugu rubripes	62.40	0.00e+00	1208.00
IUUC-Tsy-119193	Tarsius syrichta	92.67	0.00e+00	1867.00
IUUC-Tni-119790	Tetraodon nigroviridis	81.37	0.00e+00	872.00
IUUC-Tca-120920	Theobroma cacao	40.43	2.00e-05	42.40
IUUC-Tbe-127445	Tupaia belangeri	89.05	0.00e+00	1509.00
IUUC-Ttr-128877	Tursiops truncatus	93.74	0.00e+00	1863.00
IUUC-Xtr-132274	Xenopus tropicalis	77.30	0.00e+00	1565.00
IUUC-Xma-134230	Xiphophorus maculatus	61.04	0.00e+00	1164.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence