iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-119970

Ensembl Protein ID

ENSTNIP00000018287.1

UniProt Accession

H3DCP4; H3DCP4_TETNG

Protein Name

Histone-lysine N-methyltransferase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000015229.1	ENSTNIT00000018512.1	ENSTNIP00000018287.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.40e-25	87.8	171	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrsk 54
           k+C  C+++ged+ ++++C+ C++ +H  Cl+++  ++lp++  w C++Cr +
   Q: 171  KICQTCKNPGEDT-KMLVCDMCDKGYHTFCLQPA-IDSLPTNG-WRCKNCRVC 220
           79*********87.6*******************.99*****8.******965 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

DRTSRFWDEL SHVGLPQHLN VQSLFDFLGQ CWAHQSCALW SEGVFQGEGQ SLLNVDRAIY 60
SGSTKHCAYC KRLGASIKCC AEGCAQLYHY PCAGAAGTFQ DIRSFSLLCP EHTEQAIHKF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACCGAACCA GTCGATTTTG GGATGAGCTG TCTCACGTTG GCCTTCCTCA ACATCTCAAC 60
GTCCAGTCTC TCTTTGAGTC AGGTAAAATC ATTGATTCTA CATCGGCCTG ACCTGCACCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00184--RING
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	46.19	0.00e+00	1301.00
IUUC-Apl-003311	Anas platyrhynchos	53.54	0.00e+00	1384.00
IUUC-Aca-004705	Anolis carolinensis	45.82	0.00e+00	1465.00
IUUC-Ame-010612	Astyanax mexicanus	57.59	0.00e+00	682.00
IUUC-Bta-012322	Bos taurus	47.56	0.00e+00	1502.00
IUUC-Bol-015791	Brassica oleracea	29.00	7.00e-28	119.00
IUUC-Cel-018354	Caenorhabditis elegans	35.17	3.00e-61	231.00
IUUC-Cja-019983	Callithrix jacchus	45.99	0.00e+00	1718.00
IUUC-Cfa-020903	Canis familiaris	46.79	0.00e+00	1332.00
IUUC-Cpo-021732	Cavia porcellus	60.07	0.00e+00	1154.00
IUUC-Csa-023083	Chlorocebus sabaeus	50.77	0.00e+00	1348.00
IUUC-Cho-024469	Choloepus hoffmanni	38.52	0.00e+00	684.00
IUUC-Dre-027995	Danio rerio	51.49	0.00e+00	2100.00
IUUC-Dno-029932	Dasypus novemcinctus	58.77	0.00e+00	699.00
IUUC-Dor-030569	Dipodomys ordii	50.52	0.00e+00	1045.00
IUUC-Ete-032572	Echinops telfairi	57.84	2.00e-163	572.00
IUUC-Eca-033945	Equus caballus	44.72	0.00e+00	1290.00
IUUC-Fca-035922	Felis catus	43.70	0.00e+00	1659.00
IUUC-Fal-037179	Ficedula albicollis	57.46	0.00e+00	669.00
IUUC-Gmo-039403	Gadus morhua	71.65	0.00e+00	2625.00
IUUC-Gac-041896	Gasterosteus aculeatus	73.63	0.00e+00	3609.00
IUUC-Ggo-044812	Gorilla gorilla	53.43	0.00e+00	1432.00
IUUC-Hsa-046595	Homo sapiens	45.98	0.00e+00	1730.00
IUUC-Itr-048303	Ictidomys tridecemlineatus	46.76	0.00e+00	1319.00
IUUC-Lch-050086	Latimeria chalumnae	46.93	0.00e+00	1253.00
IUUC-Loc-052891	Lepisosteus oculatus	55.21	0.00e+00	1968.00
IUUC-Laf-054348	Loxodonta africana	43.24	0.00e+00	1097.00
IUUC-Mcc-054868	Macaca mulatta	45.42	0.00e+00	1701.00
IUUC-Meu-055992	Macropus eugenii	60.07	0.00e+00	672.00
IUUC-Mga-059541	Meleagris gallopavo	47.97	0.00e+00	1320.00
IUUC-Mmr-061092	Microcebus murinus	47.20	0.00e+00	2636.00
IUUC-Mdo-062610	Monodelphis domestica	58.96	0.00e+00	732.00
IUUC-Mmu-063666	Mus musculus	44.13	0.00e+00	1265.00
IUUC-Mpu-066366	Mustela putorius furo	44.55	0.00e+00	1310.00
IUUC-Mlu-068201	Myotis lucifugus	47.33	0.00e+00	1274.00
IUUC-Nle-069232	Nomascus leucogenys	46.94	0.00e+00	2551.00
IUUC-Opr-070304	Ochotona princeps	50.00	2.00e-151	532.00
IUUC-Ont-072401	Oreochromis niloticus	69.64	0.00e+00	3246.00
IUUC-Oan-072945	Ornithorhynchus anatinus	45.30	0.00e+00	1251.00
IUUC-Ocu-074920	Oryctolagus cuniculus	45.91	0.00e+00	1474.00
IUUC-Ola-086436	Oryzias latipes	67.30	0.00e+00	3426.00
IUUC-Oga-088637	Otolemur garnettii	47.41	0.00e+00	1321.00
IUUC-Oar-089363	Ovis aries	47.50	0.00e+00	1488.00
IUUC-Ptr-091527	Pan troglodytes	45.89	0.00e+00	1721.00
IUUC-Pan-092102	Papio anubis	43.64	0.00e+00	1645.00
IUUC-Pfo-096288	Poecilia formosa	73.11	0.00e+00	3310.00
IUUC-Pab-098241	Pongo abelii	45.99	0.00e+00	1800.00
IUUC-Pca-100103	Procavia capensis	61.90	0.00e+00	912.00
IUUC-Pva-102238	Pteropus vampyrus	54.36	0.00e+00	1008.00
IUUC-Rno-105660	Rattus norvegicus	58.56	0.00e+00	655.00
IUUC-Sha-106550	Sarcophilus harrisii	45.53	0.00e+00	1600.00
IUUC-Sly-111109	Solanum lycopersicum	28.63	5.00e-26	112.00
IUUC-Sar-113183	Sorex araneus	68.00	1.00e-104	376.00
IUUC-Ssc-115678	Sus scrofa	58.66	0.00e+00	693.00
IUUC-Tgu-116677	Taeniopygia guttata	47.40	0.00e+00	1309.00
IUUC-Tru-118037	Takifugu rubripes	84.33	0.00e+00	3369.00
IUUC-Tsy-118932	Tarsius syrichta	58.40	0.00e+00	1146.00
IUUC-Tbe-127625	Tupaia belangeri	53.57	1.00e-76	284.00
IUUC-Ttr-129051	Tursiops truncatus	46.70	0.00e+00	2400.00
IUUC-Vpa-130236	Vicugna pacos	48.69	0.00e+00	638.00
IUUC-Xtr-132455	Xenopus tropicalis	55.50	0.00e+00	675.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence