iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007029

UUCD1 version

UUC-ArT-00080

Ensembl Protein ID

AT2G31770.1

UniProt Accession

Q9SKC3; A0MER2; ARI9_ARATH

Genbank Protein ID

CAD52891.1; AAD32295.1; AEC08582.1; ABE65878.1; ABK28520.1

Protein Name

Probable E3 ubiquitin-protein ligase ARI9; ARIADNE-like protein ARI9; Protein ariadne homolog 9; RING-type E3 ubiquitin transferase ARI9

Genbank Nucleotide ID

AJ510212; AC006533; CP002685; DQ446586; DQ653034

Gene Name

ARI9; At2g31770; F20M17.19

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G31770	AT2G31770.1	AT2G31770.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	16339806

Classification

Family	E-value	Score	Start	End
E3 activity/RBR	3.20e-47	161.6	128	317

Active Site

Position(s)	Description	Evidence
300	N/A	{ECO:0000250\|UniProtKB:Q9Y4X5}

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqv.teiscpaaecpekleeseikellveeelykryekllleevveadaalk 89
           C +C+ +++ ee+   ++C h +Ck C+  y+++ki++g    +++cp+++c++ + ++ i+  ++e+++ ++y+++ l+++ve  +++k
   Q: 128  CGICFESYTREEIAR-VSCGHPYCKTCWAGYITTKIEDGPGcLRVKCPEPSCSAAVGKDMIED-VTETKVNEKYSRYILRSYVEDGKKIK 215
           99***9999988875.5*********************987699*******************.7************************* PP
   S: 90   wcpapdCslvvllekea.eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCn 178
           wcp p+C ++v +  ++ ++  v+c  c+  fC++C+e +H++++C++++++  k++   +e+e+k+++ ansk+Cp+Ck +iekn+gCn
   Q: 216  WCPSPGCGYAVEFGGSEsSSYDVSC-LCSYRFCWNCSEDAHSPVDCDTVSKWIFKNQ---DESENKNWMLANSKPCPECKRPIEKNDGCN 301
           ***********99887647778889.9*****************************9...99**************************** PP
   S: 179  hmtC.akCkaefCwlC 193
           hmtC a C++efCw+C
   Q: 302  HMTCsAPCGHEFCWIC 317
           ****889********* PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.

Protein Sequence
(Fasta)

MDFSDDDMID NKSGEENYSY GGGNESDDYN DVVDTIIPSE KSYVILKEED ILKLQRDDIE 60
RVSSILSLSQ VEVIVLLLHY NWCVSKVEDE WFTDEERIRK AVGLLKEPVV DFNGGEKDKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACTTTT CAGATGATGA CATGATTGAT AACAAATCAG GGGAGGAGAA TTACAGCTAT 60
GGTGGTGGTA ACGAATCCGA TGACTACAAC GATGTGGTAG ACACAATTAT TCCATCGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ath:AT2G31770

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007926	Ashbya gossypii	29.31	8.00e-46	177.00
IUUC-Bra-017053	Brassica rapa	66.47	0.00e+00	654.00
IUUC-Eeu-035166	Erinaceus europaeus	26.85	2.00e-30	128.00
IUUC-Gac-042014	Gasterosteus aculeatus	29.55	5.00e-53	201.00
IUUC-Kpa-049350	Komagataella pastoris	29.27	6.00e-50	191.00
IUUC-Lch-049584	Latimeria chalumnae	29.84	5.00e-54	204.00
IUUC-Pfo-097256	Poecilia formosa	29.77	2.00e-51	196.00
IUUC-Ssl-108406	Sclerotinia sclerotiorum	26.67	1.00e-09	57.40
IUUC-Tru-117976	Takifugu rubripes	28.70	5.00e-53	201.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence