iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000048154.16	ENSMUST00000023741.15	ENSMUSP00000023741.8
ENSMUSG00000048154.16	ENSMUST00000191973.1	ENSMUSP00000142312.1
ENSMUSG00000048154.16	ENSMUST00000184363.2	ENSMUSP00000139020.1
ENSMUSG00000048154.16	ENSMUST00000178486.8	ENSMUSP00000135941.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
HINT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.50e-28	99.8	1462	1513

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
            C+vC++++ +e+ l++C++C++w+H++C +l  e+e+++  +  + C +C+
   Q: 1462 TCPVCHAPYVEEDLLIQCRHCERWMHAGCESLFTEDEVEQAADegFDCVSCQ 1513
           6********************************888888877778******7 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MDSQKPPAED KDSDPAADGL AAPEKPGATE PDLPILCIGE VSVPGSGGSR PQKPPHDCSR 60
GPARRCALCN CGEPGLHGQR ELQRFELPSD WPGFPVVPSG GNSGPCEAVL PKEDASQIGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTTTTTTT TTTTTTTTTT TAAACCCCCG GGGGAAGGGT GACCACTCCG ACCTGGATTT 60
ACCGTTCTTG GTCTCCCTAA GCCCCCCCGA GTGGGGGGCG GCTGTGCTCG CTCTGGCGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011989--ARM-like
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR029063--SAM-dependent_MTases
IPR001214--SET_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00184--RING
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0008284--P:positive regulation of cell proliferation
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043627--P:response to estrogen

KEGG

mmu:381022

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001806	Ailuropoda melanoleuca	88.66	0.00e+00	3444.00
IUUC-Aca-005364	Anolis carolinensis	91.99	0.00e+00	1086.00
IUUC-Ame-010612	Astyanax mexicanus	81.00	0.00e+00	1010.00
IUUC-Bta-013011	Bos taurus	86.38	0.00e+00	3357.00
IUUC-Cel-018354	Caenorhabditis elegans	37.35	8.00e-64	240.00
IUUC-Cja-019841	Callithrix jacchus	86.98	0.00e+00	3628.00
IUUC-Cfa-021131	Canis familiaris	88.72	0.00e+00	3546.00
IUUC-Cpo-021957	Cavia porcellus	86.13	0.00e+00	3674.00
IUUC-Csa-023722	Chlorocebus sabaeus	87.77	0.00e+00	3554.00
IUUC-Dno-029932	Dasypus novemcinctus	89.17	0.00e+00	1598.00
IUUC-Dor-030192	Dipodomys ordii	82.46	0.00e+00	1672.00
IUUC-Ete-032572	Echinops telfairi	82.16	0.00e+00	1899.00
IUUC-Eca-034166	Equus caballus	91.33	1.00e-179	623.00
IUUC-Eeu-034848	Erinaceus europaeus	90.77	0.00e+00	1291.00
IUUC-Fca-035424	Felis catus	88.61	0.00e+00	3523.00
IUUC-Fal-037179	Ficedula albicollis	66.64	0.00e+00	1102.00
IUUC-Gmo-038719	Gadus morhua	82.21	0.00e+00	912.00
IUUC-Gga-040815	Gallus gallus	61.05	0.00e+00	1229.00
IUUC-Gac-042436	Gasterosteus aculeatus	79.50	0.00e+00	994.00
IUUC-Ggo-044711	Gorilla gorilla	88.90	0.00e+00	3461.00
IUUC-Hsa-046567	Homo sapiens	88.44	0.00e+00	3494.00
IUUC-Itr-048510	Ictidomys tridecemlineatus	88.40	0.00e+00	3531.00
IUUC-Loc-051979	Lepisosteus oculatus	82.47	0.00e+00	1055.00
IUUC-Laf-054377	Loxodonta africana	86.84	0.00e+00	3435.00
IUUC-Mcc-055577	Macaca mulatta	86.85	0.00e+00	3468.00
IUUC-Meu-055992	Macropus eugenii	82.99	0.00e+00	1279.00
IUUC-Mmr-061772	Microcebus murinus	84.79	0.00e+00	3432.00
IUUC-Mdo-062876	Monodelphis domestica	81.88	0.00e+00	1112.00
IUUC-Mpu-066700	Mustela putorius furo	88.33	0.00e+00	3453.00
IUUC-Mlu-068180	Myotis lucifugus	87.52	0.00e+00	3532.00
IUUC-Nle-069362	Nomascus leucogenys	87.95	0.00e+00	3525.00
IUUC-Opr-070304	Ochotona princeps	84.37	0.00e+00	3321.00
IUUC-Ont-071881	Oreochromis niloticus	64.30	0.00e+00	1392.00
IUUC-Oan-073663	Ornithorhynchus anatinus	85.66	0.00e+00	906.00
IUUC-Ocu-074053	Oryctolagus cuniculus	82.85	0.00e+00	3471.00
IUUC-Ola-086384	Oryzias latipes	59.56	0.00e+00	1323.00
IUUC-Oga-088450	Otolemur garnettii	84.99	0.00e+00	3635.00
IUUC-Oar-089975	Ovis aries	91.86	0.00e+00	2000.00
IUUC-Ptr-091073	Pan troglodytes	87.85	0.00e+00	3528.00
IUUC-Pan-092871	Papio anubis	85.57	0.00e+00	3516.00
IUUC-Pfo-097525	Poecilia formosa	61.93	0.00e+00	1302.00
IUUC-Pab-097679	Pongo abelii	88.84	0.00e+00	3466.00
IUUC-Pca-100499	Procavia capensis	88.16	0.00e+00	2070.00
IUUC-Pva-102898	Pteropus vampyrus	87.89	0.00e+00	3404.00
IUUC-Rno-105660	Rattus norvegicus	94.21	0.00e+00	3902.00
IUUC-Sha-107431	Sarcophilus harrisii	81.77	0.00e+00	1996.00
IUUC-Sbi-113816	Sorghum bicolor	31.31	2.00e-13	71.60
IUUC-Ssc-115678	Sus scrofa	87.95	0.00e+00	3365.00
IUUC-Tru-117922	Takifugu rubripes	80.39	0.00e+00	1011.00
IUUC-Tsy-118905	Tarsius syrichta	80.55	0.00e+00	1546.00
IUUC-Tbe-127625	Tupaia belangeri	74.10	6.00e-179	624.00
IUUC-Ttr-129162	Tursiops truncatus	88.69	0.00e+00	2006.00
IUUC-Xtr-132455	Xenopus tropicalis	63.28	0.00e+00	1303.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence