iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069181

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01080156

Gene Name

KLHL21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000008603.1	ENSNLET00000011013.1	ENSNLEP00000010500.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.90e-19	69.8	36	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.70e-09	35.2	136	164

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    Dvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           Dv+l+ + g+ f+ah++vLaa+S++F+a+f ++l+es+  ++v +++v p+ ++ ll+F+Ytg++ 
   Q: 36   DVTLEAAgGRDFPAHRAVLAAASPYFRAMFAGQLRESR-AERVRLHGVPPDMLQLLLDFSYTGRVA 100
           9*****99******************************.************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkh 30
            Ncl++ +fA++++c+ L++aa++fil+h
   Q: 136  ANCLDMQDFAEAFSCSGLASAAQRFILRH 164
           6***************************9 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MERPAPLAVL PFSDPAHALS LLRGLSQLRA ERKFLDVTLE AAGGRDFPAH RAVLAAASPY 60
FRAMFAGQLR ESRAERVRLH GVPPDMLQLL LDFSYTGRVA VSGDNAEPLL RAADLLQFPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCGAC CGGCGCCCCT GGCCGTGCTG CCCTTCTCGG ACCCCGCGCA TGCCCTGAGC 60
CTGCTGCGCG GCCTGAGCCA GCTCCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035853--P:chromosome passenger complex localization to spindle midzone
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001782	Ailuropoda melanoleuca	87.25	0.00e+00	914.00
IUUC-Apl-003189	Anas platyrhynchos	83.33	1.00e-142	498.00
IUUC-Ani-009467	Aspergillus nidulans	35.29	7.00e-08	51.20
IUUC-Ame-011774	Astyanax mexicanus	64.43	2.00e-131	461.00
IUUC-Bta-012367	Bos taurus	96.15	0.00e+00	1138.00
IUUC-Cja-019501	Callithrix jacchus	90.74	0.00e+00	1048.00
IUUC-Cfa-020550	Canis familiaris	96.15	0.00e+00	1137.00
IUUC-Cpo-022072	Cavia porcellus	95.48	0.00e+00	1110.00
IUUC-Csa-023364	Chlorocebus sabaeus	98.65	0.00e+00	1013.00
IUUC-Cin-025253	Ciona intestinalis	43.37	6.00e-146	510.00
IUUC-Csv-025871	Ciona savignyi	45.19	2.00e-151	529.00
IUUC-Dre-028694	Danio rerio	71.65	0.00e+00	844.00
IUUC-Dno-029082	Dasypus novemcinctus	92.79	0.00e+00	934.00
IUUC-Dor-030680	Dipodomys ordii	95.81	0.00e+00	1134.00
IUUC-Ete-032315	Echinops telfairi	93.87	0.00e+00	944.00
IUUC-Eca-033570	Equus caballus	93.47	0.00e+00	677.00
IUUC-Eeu-035067	Erinaceus europaeus	94.14	3.00e-147	515.00
IUUC-Fca-035663	Felis catus	91.91	2.00e-127	447.00
IUUC-Fal-037103	Ficedula albicollis	82.06	0.00e+00	880.00
IUUC-Gmo-039420	Gadus morhua	67.97	0.00e+00	820.00
IUUC-Ggr-039811	Gaeumannomyces graminis	38.36	3.00e-08	52.80
IUUC-Gga-040161	Gallus gallus	81.29	0.00e+00	849.00
IUUC-Gac-041755	Gasterosteus aculeatus	70.47	0.00e+00	844.00
IUUC-Ggo-044899	Gorilla gorilla	98.32	0.00e+00	1137.00
IUUC-Hsa-045834	Homo sapiens	98.79	0.00e+00	1131.00
IUUC-Itr-048413	Ictidomys tridecemlineatus	96.31	0.00e+00	1136.00
IUUC-Lch-050338	Latimeria chalumnae	68.60	0.00e+00	856.00
IUUC-Loc-051780	Lepisosteus oculatus	73.99	0.00e+00	859.00
IUUC-Laf-053725	Loxodonta africana	92.75	0.00e+00	769.00
IUUC-Mcc-055032	Macaca mulatta	98.60	0.00e+00	969.00
IUUC-Meu-056661	Macropus eugenii	93.02	0.00e+00	751.00
IUUC-Mpo-057626	Magnaporthe poae	31.67	4.00e-07	49.70
IUUC-Mga-059821	Meleagris gallopavo	83.13	2.00e-127	447.00
IUUC-Mdo-062095	Monodelphis domestica	93.68	0.00e+00	940.00
IUUC-Mmu-063138	Mus musculus	95.81	0.00e+00	1132.00
IUUC-Mpu-066386	Mustela putorius furo	94.41	0.00e+00	632.00
IUUC-Mlu-067807	Myotis lucifugus	93.54	0.00e+00	685.00
IUUC-Opr-070658	Ochotona princeps	95.81	0.00e+00	1159.00
IUUC-Ont-072209	Oreochromis niloticus	70.60	0.00e+00	832.00
IUUC-Oan-072861	Ornithorhynchus anatinus	90.70	9.00e-119	419.00
IUUC-Ocu-074631	Oryctolagus cuniculus	87.02	0.00e+00	993.00
IUUC-Ola-087553	Oryzias latipes	69.37	0.00e+00	819.00
IUUC-Oga-088782	Otolemur garnettii	95.98	0.00e+00	1137.00
IUUC-Oar-089634	Ovis aries	95.81	0.00e+00	1133.00
IUUC-Ptr-091259	Pan troglodytes	97.98	0.00e+00	842.00
IUUC-Pan-091734	Papio anubis	98.32	0.00e+00	1137.00
IUUC-Psi-092979	Pelodiscus sinensis	81.95	0.00e+00	902.00
IUUC-Pma-094459	Petromyzon marinus	51.74	6.00e-120	424.00
IUUC-Pno-094945	Phaeosphaeria nodorum	34.85	4.00e-06	44.70
IUUC-Pfo-097446	Poecilia formosa	70.42	0.00e+00	831.00
IUUC-Pab-098765	Pongo abelii	98.66	0.00e+00	1165.00
IUUC-Pca-101018	Procavia capensis	99.42	6.00e-94	338.00
IUUC-Pva-102730	Pteropus vampyrus	93.30	0.00e+00	1095.00
IUUC-Rno-104972	Rattus norvegicus	95.14	0.00e+00	1127.00
IUUC-Ssc-115869	Sus scrofa	96.82	0.00e+00	961.00
IUUC-Tgu-116562	Taeniopygia guttata	81.90	0.00e+00	912.00
IUUC-Tru-118490	Takifugu rubripes	69.89	0.00e+00	825.00
IUUC-Tni-119898	Tetraodon nigroviridis	68.13	0.00e+00	793.00
IUUC-Ttr-128976	Tursiops truncatus	94.53	5.00e-147	514.00
IUUC-Xtr-132876	Xenopus tropicalis	73.69	0.00e+00	890.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence