iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005143

UUCD1 version

UUC-AnC-00019

Ensembl Protein ID

ENSACAP00000000569.3

UniProt Accession

H9G3Z8; H9G3Z8_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000000301.3	ENSACAT00000000588.3	ENSACAP00000000569.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.30e-21	76.7	57	124
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.60e-11	43.3	157	187

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv++v ++ e+ ah++vLaa+S++F+a+f++e++es+ +++v ik+v+   ++ l++F+Ytg+++ +e
   Q: 57   CDVTIVAEDMEIAAHRVVLAACSPYFHAMFTGEMSESQ-SKRVRIKEVDGWTLKMLIEFVYTGEIQVTE 124
           8************************************9.*************************99865 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
            Nclgi++fAd++ c +L  +a++++++hF+
   Q: 157  VNCLGIRAFADMHACIELLNKANTYAEQHFT 187
           6*****************************7 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MEMLLLQPLG CSKLCQQKPP NLQDDDTEKH CPVTVNPWHM KKAFRIMNEL RSQDLLCDVT 60
IVAEDMEIAA HRVVLAACSP YFHAMFTGEM SESQSKRVRI KEVDGWTLKM LIEFVYTGEI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGCTGCA CGTAAGAGTG CGTGATGACG TCACTGCCCT AGCCAGGATA AGCGGGTTTG 60
GTTCCCGAAC CCCGGAAGTG GCGGCTTCAG TCGAATTCAG CAGCCGAAGG AGGAGGACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0003779--F:actin binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

acs:100551954

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002378	Ailuropoda melanoleuca	88.59	0.00e+00	1064.00
IUUC-Apl-003260	Anas platyrhynchos	88.70	0.00e+00	1063.00
IUUC-Cja-018942	Callithrix jacchus	88.74	0.00e+00	1068.00
IUUC-Cfa-020886	Canis familiaris	89.21	0.00e+00	1069.00
IUUC-Cpo-022543	Cavia porcellus	88.76	0.00e+00	1070.00
IUUC-Csa-023088	Chlorocebus sabaeus	88.76	0.00e+00	1068.00
IUUC-Dre-028082	Danio rerio	80.65	0.00e+00	965.00
IUUC-Dno-029873	Dasypus novemcinctus	86.90	0.00e+00	1042.00
IUUC-Dor-030460	Dipodomys ordii	71.23	0.00e+00	782.00
IUUC-Dse-031229	Dothistroma septosporum	35.71	1.00e-07	49.30
IUUC-Dme-032172	Drosophila melanogaster	59.93	0.00e+00	656.00
IUUC-Eca-033798	Equus caballus	88.53	0.00e+00	1061.00
IUUC-Eeu-034824	Erinaceus europaeus	83.24	0.00e+00	900.00
IUUC-Fca-036455	Felis catus	89.21	0.00e+00	1069.00
IUUC-Fal-037293	Ficedula albicollis	88.47	0.00e+00	1004.00
IUUC-Gmo-038811	Gadus morhua	76.75	0.00e+00	864.00
IUUC-Gga-040805	Gallus gallus	88.01	0.00e+00	1055.00
IUUC-Gac-041979	Gasterosteus aculeatus	78.85	0.00e+00	865.00
IUUC-Ggo-044620	Gorilla gorilla	84.21	0.00e+00	1010.00
IUUC-Hsa-046265	Homo sapiens	88.76	0.00e+00	1068.00
IUUC-Lch-049939	Latimeria chalumnae	81.51	0.00e+00	956.00
IUUC-Loc-052780	Lepisosteus oculatus	83.53	0.00e+00	1008.00
IUUC-Laf-053800	Loxodonta africana	89.04	0.00e+00	1066.00
IUUC-Mcc-055732	Macaca mulatta	87.99	0.00e+00	1053.00
IUUC-Meu-056011	Macropus eugenii	90.04	0.00e+00	997.00
IUUC-Mvi-060512	Microbotryum violaceum	25.42	5.00e-06	46.60
IUUC-Mmr-061067	Microcebus murinus	88.05	0.00e+00	1054.00
IUUC-Mdo-062977	Monodelphis domestica	88.22	0.00e+00	1075.00
IUUC-Mmu-064035	Mus musculus	87.74	0.00e+00	1043.00
IUUC-Mpu-066726	Mustela putorius furo	89.04	0.00e+00	1067.00
IUUC-Mlu-067020	Myotis lucifugus	88.46	0.00e+00	1067.00
IUUC-Nle-069456	Nomascus leucogenys	89.04	0.00e+00	1067.00
IUUC-Opr-071130	Ochotona princeps	80.48	0.00e+00	935.00
IUUC-Ont-072219	Oreochromis niloticus	79.08	0.00e+00	920.00
IUUC-Oan-073699	Ornithorhynchus anatinus	89.37	0.00e+00	919.00
IUUC-Ocu-074045	Oryctolagus cuniculus	88.76	0.00e+00	1068.00
IUUC-Oga-088494	Otolemur garnettii	89.21	0.00e+00	1066.00
IUUC-Oar-089645	Ovis aries	88.23	0.00e+00	1061.00
IUUC-Ptr-091063	Pan troglodytes	88.76	0.00e+00	1068.00
IUUC-Psi-093946	Pelodiscus sinensis	88.23	0.00e+00	1066.00
IUUC-Pfo-096817	Poecilia formosa	78.12	0.00e+00	924.00
IUUC-Pab-097768	Pongo abelii	88.59	0.00e+00	1066.00
IUUC-Pca-100607	Procavia capensis	72.08	0.00e+00	739.00
IUUC-Pva-102218	Pteropus vampyrus	83.30	0.00e+00	991.00
IUUC-Rno-105250	Rattus norvegicus	88.07	0.00e+00	1058.00
IUUC-Sar-113249	Sorex araneus	88.70	0.00e+00	1047.00
IUUC-Ssc-115423	Sus scrofa	88.70	0.00e+00	1064.00
IUUC-Tgu-117050	Taeniopygia guttata	87.01	0.00e+00	1046.00
IUUC-Tru-118239	Takifugu rubripes	77.80	0.00e+00	957.00
IUUC-Tsy-119377	Tarsius syrichta	76.54	0.00e+00	917.00
IUUC-Tni-120122	Tetraodon nigroviridis	78.12	0.00e+00	861.00
IUUC-Vpa-130707	Vicugna pacos	86.70	0.00e+00	810.00
IUUC-Xtr-132035	Xenopus tropicalis	82.91	0.00e+00	1015.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence