iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062585

UUCD1 version

UUC-MoD-00148

Ensembl Protein ID

ENSMODP00000024090.2

UniProt Accession

F6RYQ1; F6RYQ1_MONDO

Protein Name

Uncharacterized protein

Gene Name

TRAF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000019302.2	ENSMODT00000024517.2	ENSMODP00000024090.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.10e-06	26.8	18	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C   +++++ v  CgH f+ +Clq +     +s + f+CP 
   Q: 18   CPLCAKAMREPVQVSTCGHRFCDTCLQEF-----LSEGVFKCPE 56
           ********99888888**********999.....89*******6 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MPGFDYKFLE KPKRRLLCPL CAKAMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKIYPDP ELEAQVLSLP IRCIHSEEGC RWTGALRQLQ VHLSSCGYNV VACPNRCNGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGACCCCGG CCGCCCGGCC GCCCACCATG CCGGGCTTCG ACTACAAGTT CCTGGAGAAG 60
CCCAAGCGGC GGCTGCTGTG CCCGCTGTGC GCCAAGGCCA TGCGGGAGCC CGTGCAGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0042981--P:regulation of apoptotic process
GO:0007585--P:respiratory gaseous exchange
GO:0030323--P:respiratory tube development

KEGG

mdo:100020121

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001287	Ailuropoda melanoleuca	86.35	0.00e+00	822.00
IUUC-Aly-006415	Arabidopsis lyrata	33.66	2.00e-07	51.20
IUUC-Ath-007062	Arabidopsis thaliana	33.66	3.00e-07	50.40
IUUC-Ame-011530	Astyanax mexicanus	77.23	0.00e+00	776.00
IUUC-Bta-013582	Bos taurus	87.66	0.00e+00	838.00
IUUC-Bdi-014617	Brachypodium distachyon	25.71	5.00e-07	50.40
IUUC-Cfa-020133	Canis familiaris	83.40	0.00e+00	782.00
IUUC-Cpo-022021	Cavia porcellus	87.45	0.00e+00	840.00
IUUC-Csa-023199	Chlorocebus sabaeus	87.45	0.00e+00	839.00
IUUC-Cne-026870	Cryptococcus neoformans	26.77	1.00e-18	88.60
IUUC-Dre-028193	Danio rerio	76.38	0.00e+00	772.00
IUUC-Dno-028917	Dasypus novemcinctus	87.66	0.00e+00	843.00
IUUC-Ete-032433	Echinops telfairi	85.96	0.00e+00	827.00
IUUC-Fca-036155	Felis catus	87.87	0.00e+00	843.00
IUUC-Gmo-038860	Gadus morhua	76.38	0.00e+00	767.00
IUUC-Gga-041052	Gallus gallus	79.57	0.00e+00	819.00
IUUC-Gac-041489	Gasterosteus aculeatus	76.60	0.00e+00	769.00
IUUC-Ggo-044996	Gorilla gorilla	86.60	0.00e+00	833.00
IUUC-Hsa-046252	Homo sapiens	86.81	0.00e+00	836.00
IUUC-Hvu-047127	Hordeum vulgare	31.82	2.00e-07	49.70
IUUC-Itr-048232	Ictidomys tridecemlineatus	87.66	0.00e+00	842.00
IUUC-Kpa-049340	Komagataella pastoris	24.08	3.00e-14	73.20
IUUC-Loc-052312	Lepisosteus oculatus	77.07	0.00e+00	772.00
IUUC-Laf-054376	Loxodonta africana	87.45	0.00e+00	838.00
IUUC-Mcc-055684	Macaca mulatta	87.45	0.00e+00	839.00
IUUC-Mmr-061198	Microcebus murinus	87.66	0.00e+00	842.00
IUUC-Mmu-064303	Mus musculus	87.66	0.00e+00	843.00
IUUC-Mac-064529	Musa acuminata	29.60	5.00e-09	55.10
IUUC-Mpu-066854	Mustela putorius furo	88.09	0.00e+00	843.00
IUUC-Nle-070098	Nomascus leucogenys	85.53	0.00e+00	823.00
IUUC-Ont-071518	Oreochromis niloticus	76.97	0.00e+00	771.00
IUUC-Ocu-073841	Oryctolagus cuniculus	87.66	0.00e+00	843.00
IUUC-Oba-075263	Oryza barthii	32.94	5.00e-07	48.50
IUUC-Obr-076500	Oryza brachyantha	35.90	2.00e-08	53.10
IUUC-Ogu-078582	Oryza glumaepatula	32.94	5.00e-07	48.50
IUUC-Oin-079499	Oryza indica	32.94	5.00e-07	48.50
IUUC-Ome-081269	Oryza meridionalis	34.12	1.00e-07	50.80
IUUC-Opu-083468	Oryza punctata	34.12	7.00e-08	51.60
IUUC-Oru-084662	Oryza rufipogon	32.94	7.00e-07	48.50
IUUC-Osa-085740	Oryza sativa	32.94	5.00e-07	48.50
IUUC-Ola-086674	Oryzias latipes	77.61	0.00e+00	773.00
IUUC-Oga-088510	Otolemur garnettii	87.45	0.00e+00	838.00
IUUC-Oar-089225	Ovis aries	85.11	0.00e+00	801.00
IUUC-Pan-092725	Papio anubis	87.45	0.00e+00	839.00
IUUC-Pfo-096341	Poecilia formosa	76.55	0.00e+00	769.00
IUUC-Pva-103131	Pteropus vampyrus	88.17	5.00e-131	461.00
IUUC-Rno-105996	Rattus norvegicus	87.87	0.00e+00	843.00
IUUC-Sbi-113900	Sorghum bicolor	37.14	1.00e-07	50.40
IUUC-Tru-117602	Takifugu rubripes	77.02	0.00e+00	775.00
IUUC-Tur-126067	Triticum urartu	34.12	6.00e-08	51.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence