iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062945

Ensembl Protein ID

ENSMODP00000022937.3

UniProt Accession

F6QU82; F6QU82_MONDO

Protein Name

Uncharacterized protein

Gene Name

KDM5A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000018390.4	ENSMODT00000023343.3	ENSMODP00000022937.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.50e-14	51.8	294	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vC +Cg+g +++ +l+ C+ C++ +H  Cl ++  +++p+ + w CpkC +
   Q: 294  VCMFCGRGNNED-KLLLCDGCDDSYHTFCLIPP-LPDVPKGD-WRCPKCVA 341
           8*********88.6*******************.*******7.******75 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAGAGPGGYA AEFVPPPECP VFEPSWEEFT DPLSFIGRIR PLAEKTGICK IRPPKDWQPP 60
FACEVKSFRF TPRVQRLNEL EAMTRVRLDF LDQLAKFWEL QGSTLKIPVV ERKILDLYAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACATTCCTC CGCGCCGGAA GAACGCGGCG TCTTTTTTCC GCTTTTTCCC TCTGTCCAAT 60
ATTACTCTGA TTCCTTGTAG CTCTCCCCCG TCTTTCCCAA AGTTGGGGTG GGTGGATTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002061	Ailuropoda melanoleuca	95.75	0.00e+00	2774.00
IUUC-Atr-002595	Amborella trichopoda	30.82	7.00e-124	439.00
IUUC-Apl-004141	Anas platyrhynchos	93.30	0.00e+00	2751.00
IUUC-Aca-004952	Anolis carolinensis	91.81	0.00e+00	2753.00
IUUC-Ate-010453	Aspergillus terreus	30.22	4.00e-115	410.00
IUUC-Ame-011323	Astyanax mexicanus	76.02	0.00e+00	1996.00
IUUC-Bgr-012241	Blumeria graminis	29.16	2.00e-109	391.00
IUUC-Bta-012902	Bos taurus	95.01	0.00e+00	2803.00
IUUC-Cja-018988	Callithrix jacchus	94.82	0.00e+00	2611.00
IUUC-Cfa-020212	Canis familiaris	94.69	0.00e+00	2733.00
IUUC-Cpo-022221	Cavia porcellus	95.34	0.00e+00	1907.00
IUUC-Csa-023575	Chlorocebus sabaeus	95.81	0.00e+00	2825.00
IUUC-Cho-024280	Choloepus hoffmanni	90.88	0.00e+00	2550.00
IUUC-Cin-025321	Ciona intestinalis	49.32	0.00e+00	1095.00
IUUC-Csv-026185	Ciona savignyi	47.67	0.00e+00	1178.00
IUUC-Dre-027909	Danio rerio	75.90	0.00e+00	1657.00
IUUC-Dno-029473	Dasypus novemcinctus	95.07	0.00e+00	2659.00
IUUC-Dor-030281	Dipodomys ordii	93.60	0.00e+00	1217.00
IUUC-Dme-032021	Drosophila melanogaster	46.89	0.00e+00	1121.00
IUUC-Eca-034265	Equus caballus	94.72	0.00e+00	2781.00
IUUC-Fca-035476	Felis catus	94.44	0.00e+00	2769.00
IUUC-Fal-037078	Ficedula albicollis	92.66	0.00e+00	2532.00
IUUC-Gga-040466	Gallus gallus	92.37	0.00e+00	2815.00
IUUC-Gac-042566	Gasterosteus aculeatus	75.92	0.00e+00	2132.00
IUUC-Ggo-044524	Gorilla gorilla	88.56	0.00e+00	2352.00
IUUC-Hsa-045821	Homo sapiens	95.69	0.00e+00	2803.00
IUUC-Kpa-049245	Komagataella pastoris	22.57	2.00e-38	155.00
IUUC-Lch-050630	Latimeria chalumnae	75.17	0.00e+00	2126.00
IUUC-Loc-051963	Lepisosteus oculatus	76.47	0.00e+00	2102.00
IUUC-Laf-053918	Loxodonta africana	88.47	0.00e+00	2521.00
IUUC-Mcc-055672	Macaca mulatta	95.75	0.00e+00	2816.00
IUUC-Mtr-058113	Medicago truncatula	31.54	2.00e-95	344.00
IUUC-Mga-059192	Meleagris gallopavo	83.23	0.00e+00	2360.00
IUUC-Mmr-060968	Microcebus murinus	95.18	0.00e+00	2798.00
IUUC-Mmu-063614	Mus musculus	94.50	0.00e+00	2773.00
IUUC-Mpu-066349	Mustela putorius furo	95.69	0.00e+00	2776.00
IUUC-Mlu-067363	Myotis lucifugus	95.38	0.00e+00	2830.00
IUUC-Nle-070142	Nomascus leucogenys	95.62	0.00e+00	2804.00
IUUC-Opr-071002	Ochotona princeps	88.24	0.00e+00	1358.00
IUUC-Ont-072471	Oreochromis niloticus	78.76	0.00e+00	1894.00
IUUC-Oan-072797	Ornithorhynchus anatinus	79.89	0.00e+00	2074.00
IUUC-Ocu-074164	Oryctolagus cuniculus	94.13	0.00e+00	2831.00
IUUC-Oba-075388	Oryza barthii	28.06	5.00e-83	303.00
IUUC-Obr-076296	Oryza brachyantha	33.64	2.00e-97	352.00
IUUC-Ogu-079040	Oryza glumaepatula	27.94	7.00e-83	303.00
IUUC-Ome-081764	Oryza meridionalis	29.84	5.00e-101	363.00
IUUC-Oni-083012	Oryza nivara	28.02	2.00e-82	301.00
IUUC-Oru-084630	Oryza rufipogon	27.94	4.00e-82	300.00
IUUC-Ola-087076	Oryzias latipes	75.10	0.00e+00	2116.00
IUUC-Oga-088350	Otolemur garnettii	93.25	0.00e+00	2699.00
IUUC-Oar-090045	Ovis aries	94.88	0.00e+00	2805.00
IUUC-Ptr-091199	Pan troglodytes	94.81	0.00e+00	2793.00
IUUC-Pan-092094	Papio anubis	92.54	0.00e+00	2684.00
IUUC-Psi-093550	Pelodiscus sinensis	92.72	0.00e+00	2640.00
IUUC-Pfo-097266	Poecilia formosa	75.23	0.00e+00	2123.00
IUUC-Pab-098576	Pongo abelii	95.94	0.00e+00	2802.00
IUUC-Pca-100123	Procavia capensis	91.21	0.00e+00	1623.00
IUUC-Ppe-101504	Prunus persica	32.12	3.00e-101	363.00
IUUC-Pva-103109	Pteropus vampyrus	89.56	0.00e+00	2599.00
IUUC-Pte-104195	Pyrenophora teres	29.04	4.00e-121	430.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	28.93	4.00e-123	436.00
IUUC-Rno-105664	Rattus norvegicus	94.31	0.00e+00	2759.00
IUUC-Sha-107506	Sarcophilus harrisii	98.10	0.00e+00	2497.00
IUUC-Sja-107734	Schizosaccharomyces japonicus	20.62	5.00e-33	137.00
IUUC-Spo-108283	Schizosaccharomyces pombe	22.57	3.00e-54	207.00
IUUC-Smo-108843	Selaginella moellendorffii	52.08	9.00e-11	62.40
IUUC-Sit-110534	Setaria italica	29.71	6.00e-121	429.00
IUUC-Sar-113052	Sorex araneus	93.94	0.00e+00	2769.00
IUUC-Sbi-114173	Sorghum bicolor	58.14	7.00e-12	64.70
IUUC-Sre-115161	Sporisorium reilianum	29.56	2.00e-130	461.00
IUUC-Tgu-116613	Taeniopygia guttata	91.99	0.00e+00	2736.00
IUUC-Tru-118604	Takifugu rubripes	75.36	0.00e+00	2157.00
IUUC-Tsy-119237	Tarsius syrichta	95.45	0.00e+00	1285.00
IUUC-Tni-120779	Tetraodon nigroviridis	75.00	0.00e+00	2136.00
IUUC-Tca-121478	Theobroma cacao	31.85	2.00e-105	378.00
IUUC-Tme-127087	Tuber melanosporum	33.62	1.00e-121	432.00
IUUC-Ttr-129242	Tursiops truncatus	93.12	0.00e+00	2702.00
IUUC-Vpa-130429	Vicugna pacos	88.21	0.00e+00	1439.00
IUUC-Vvi-131071	Vitis vinifera	30.35	2.00e-81	298.00
IUUC-Xtr-131762	Xenopus tropicalis	77.30	0.00e+00	2218.00
IUUC-Xma-133693	Xiphophorus maculatus	75.27	0.00e+00	2136.00
IUUC-Zma-135829	Zea mays	29.03	8.00e-117	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence