iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-034294

Ensembl Protein ID

ENSECAP00000015138.1

UniProt Accession

F6S4B7; F6S4B7_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBXN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000017404.1	ENSECAT00000018554.1	ENSECAP00000015138.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.90e-08	34.3	4	42
ULD/UDP/UFD/UBX	4.10e-20	72.3	208	289

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +le l+eMGF++ +a +aL+ + n  +eaA+++L+++
   Q: 4    LTALESLIEMGFPKGRAEKALALTgNQGIEAAMDWLMEH 42
           5689********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++ +  +dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 208  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEEPGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 289
           578*****************************************************************************98 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAELTALESL IEMGFPKGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLAAPVGHIL 60
GREPTPSEQG GPEGPGSAAG EGKPTLSEEE RQEQTKRMLE LVAQKQRERE EREEREALER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCATGGCGG AGCTGACGGC TCTGGAGAGT CTCATAGAGA TGGGCTTCCC CAAGGGACGC 60
GCGTAAGGGA GCCCCCTAAC CCCGGCCCGC GGGGGTCACG GACCTGTCCG GGCCTTTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

KEGG

ecb:100060210

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002325	Ailuropoda melanoleuca	91.47	2.00e-112	398.00
IUUC-Aca-004329	Anolis carolinensis	70.24	4.00e-48	184.00
IUUC-Aly-005639	Arabidopsis lyrata	52.73	5.00e-12	65.50
IUUC-Ath-006887	Arabidopsis thaliana	52.73	8.00e-12	64.70
IUUC-Ago-007989	Ashbya gossypii	37.18	7.00e-07	47.80
IUUC-Ame-011399	Astyanax mexicanus	52.77	7.00e-62	230.00
IUUC-Bta-013151	Bos taurus	94.93	6.00e-126	443.00
IUUC-Bol-016537	Brassica oleracea	52.73	8.00e-12	64.70
IUUC-Bra-017906	Brassica rapa	61.36	1.00e-11	64.70
IUUC-Cel-018300	Caenorhabditis elegans	34.09	3.00e-13	68.60
IUUC-Cja-019084	Callithrix jacchus	93.66	1.00e-101	362.00
IUUC-Cfa-020997	Canis familiaris	87.28	2.00e-89	321.00
IUUC-Cpo-021736	Cavia porcellus	78.79	1.00e-81	295.00
IUUC-Csa-024040	Chlorocebus sabaeus	92.26	1.00e-100	359.00
IUUC-Cho-024543	Choloepus hoffmanni	95.54	3.00e-70	257.00
IUUC-Cin-025719	Ciona intestinalis	39.07	5.00e-36	144.00
IUUC-Csv-025854	Ciona savignyi	38.80	4.00e-35	141.00
IUUC-Cme-027235	Cyanidioschyzon merolae	45.45	9.00e-08	51.20
IUUC-Dre-027745	Danio rerio	52.51	6.00e-59	220.00
IUUC-Dno-029598	Dasypus novemcinctus	92.23	5.00e-103	367.00
IUUC-Dor-030917	Dipodomys ordii	78.87	1.00e-89	323.00
IUUC-Dme-032055	Drosophila melanogaster	41.82	9.00e-24	103.00
IUUC-Ete-032960	Echinops telfairi	78.21	2.00e-79	288.00
IUUC-Eeu-034906	Erinaceus europaeus	89.47	2.00e-103	368.00
IUUC-Fca-035653	Felis catus	89.40	8.00e-95	339.00
IUUC-Gmo-038755	Gadus morhua	50.32	4.00e-55	207.00
IUUC-Gac-042481	Gasterosteus aculeatus	54.19	1.00e-57	216.00
IUUC-Gma-042684	Glycine max	52.27	2.00e-10	60.10
IUUC-Ggo-044821	Gorilla gorilla	91.52	1.00e-93	335.00
IUUC-Hsa-046797	Homo sapiens	91.92	3.00e-102	364.00
IUUC-Itr-048850	Ictidomys tridecemlineatus	91.58	6.00e-114	403.00
IUUC-Lch-049508	Latimeria chalumnae	51.82	4.00e-58	218.00
IUUC-Laf-053932	Loxodonta africana	94.95	7.00e-131	459.00
IUUC-Mcc-055300	Macaca mulatta	91.92	1.00e-100	358.00
IUUC-Mtr-058774	Medicago truncatula	50.00	8.00e-10	57.40
IUUC-Mla-059083	Melampsora laricipopulina	28.48	5.00e-07	48.50
IUUC-Mvi-060245	Microbotryum violaceum	40.48	1.00e-11	63.90
IUUC-Mmr-060979	Microcebus murinus	91.92	5.00e-107	380.00
IUUC-Mdo-062299	Monodelphis domestica	86.62	2.00e-96	344.00
IUUC-Mmu-063212	Mus musculus	92.59	2.00e-115	408.00
IUUC-Mac-065377	Musa acuminata	51.11	1.00e-11	61.20
IUUC-Mpu-066540	Mustela putorius furo	91.89	2.00e-114	404.00
IUUC-Mlu-067589	Myotis lucifugus	93.58	2.00e-106	378.00
IUUC-Nle-069045	Nomascus leucogenys	91.70	2.00e-74	271.00
IUUC-Opr-070772	Ochotona princeps	90.11	2.00e-88	318.00
IUUC-Ont-072006	Oreochromis niloticus	53.82	4.00e-58	218.00
IUUC-Oan-073244	Ornithorhynchus anatinus	63.18	8.00e-47	180.00
IUUC-Ocu-074333	Oryctolagus cuniculus	89.90	3.00e-104	371.00
IUUC-Oba-075451	Oryza barthii	50.94	2.00e-11	63.50
IUUC-Obr-076923	Oryza brachyantha	52.94	1.00e-11	64.70
IUUC-Ogl-077259	Oryza glaberrima	39.73	3.00e-10	59.30
IUUC-Ogu-078589	Oryza glumaepatula	50.94	2.00e-11	63.50
IUUC-Oin-079151	Oryza indica	50.94	2.00e-11	63.50
IUUC-Ome-081253	Oryza meridionalis	50.94	2.00e-11	63.50
IUUC-Oni-082110	Oryza nivara	39.73	9.00e-11	60.80
IUUC-Opu-083336	Oryza punctata	50.94	2.00e-11	63.50
IUUC-Oru-085235	Oryza rufipogon	50.94	2.00e-11	63.50
IUUC-Osa-085611	Oryza sativa	50.94	2.00e-11	63.50
IUUC-Ola-086781	Oryzias latipes	53.07	2.00e-55	208.00
IUUC-Oga-088429	Otolemur garnettii	91.25	1.00e-102	366.00
IUUC-Oar-089885	Ovis aries	94.59	5.00e-126	443.00
IUUC-Ptr-091315	Pan troglodytes	91.17	1.00e-93	335.00
IUUC-Pan-092885	Papio anubis	92.26	1.00e-100	359.00
IUUC-Psi-093299	Pelodiscus sinensis	72.73	6.00e-65	240.00
IUUC-Pma-094221	Petromyzon marinus	64.37	2.00e-28	117.00
IUUC-Ppa-095484	Physcomitrella patens	51.11	2.00e-10	60.10
IUUC-Pfo-096188	Poecilia formosa	54.25	5.00e-56	211.00
IUUC-Pab-097881	Pongo abelii	84.85	4.00e-99	354.00
IUUC-Pop-098863	Populus trichocarpa	54.90	4.00e-12	65.90
IUUC-Pca-100977	Procavia capensis	91.64	6.00e-104	370.00
IUUC-Ppe-101243	Prunus persica	49.02	2.00e-10	59.70
IUUC-Pva-102169	Pteropus vampyrus	94.37	3.00e-99	354.00
IUUC-Rno-105459	Rattus norvegicus	92.59	3.00e-115	407.00
IUUC-Sha-107526	Sarcophilus harrisii	88.22	7.00e-97	346.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	26.67	1.00e-05	44.30
IUUC-Sit-110434	Setaria italica	35.23	2.00e-09	56.20
IUUC-Sly-111766	Solanum lycopersicum	47.54	4.00e-11	62.40
IUUC-Stu-112122	Solanum tuberosum	47.54	4.00e-11	62.40
IUUC-Sar-112945	Sorex araneus	93.51	1.00e-69	255.00
IUUC-Sbi-114159	Sorghum bicolor	32.46	2.00e-10	60.10
IUUC-Ssc-116114	Sus scrofa	92.93	8.00e-101	359.00
IUUC-Tru-117839	Takifugu rubripes	52.56	6.00e-54	204.00
IUUC-Tsy-118813	Tarsius syrichta	92.68	7.00e-60	223.00
IUUC-Tni-120504	Tetraodon nigroviridis	54.85	8.00e-56	210.00
IUUC-Tur-126598	Triticum urartu	51.16	2.00e-09	56.20
IUUC-Tbe-128034	Tupaia belangeri	92.61	3.00e-104	371.00
IUUC-Ttr-128468	Tursiops truncatus	88.85	9.00e-104	369.00
IUUC-Uma-129569	Ustilago maydis	34.62	1.00e-05	43.50
IUUC-Vpa-130179	Vicugna pacos	90.04	7.00e-78	283.00
IUUC-Vvi-131064	Vitis vinifera	50.98	1.00e-10	60.80
IUUC-Xtr-132119	Xenopus tropicalis	62.75	9.00e-70	256.00
IUUC-Xma-134067	Xiphophorus maculatus	53.25	4.00e-56	211.00
IUUC-Zma-134709	Zea mays	36.36	1.00e-09	57.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence