iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007670

UUCD1 version

UUC-ArT-01401

Ensembl Protein ID

AT2G39760.1

UniProt Accession

O22286; Q2V416; Q8L977; BPM3_ARATH

Genbank Protein ID

AAB87125.1; AEC09719.1; AEC09720.1; AAM91518.1; AAN15363.1; BAH19418.1; AAM66127.1

Protein Name

BTB/POZ and MATH domain-containing protein 3; Protein BTB-POZ AND MATH DOMAIN 3

Genbank Nucleotide ID

AC003000; CP002685; CP002685; AY128315; BT000044; AK316691; AY088598

Gene Name

BPM3; At2g39760; T5I7.6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G39760	AT2G39760.1	AT2G39760.1
AT2G39760	AT2G39760.4	AT2G39760.4
AT2G39760	AT2G39760.2	AT2G39760.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/BCR/BTB_3-box	BTB_3-box	15618422; 15772280

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	8.30e-20	71.8	194	259
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.20e-05	24.7	305	333

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +D+ ++vg+e ++ahk++Laa+S+vF+a f +   +++  ++++i+d++p+ f+a+l+F+Yt+ l++
   Q: 194  CDIAFQVGDETYKAHKLILAARSPVFRAQFFGPIGNNN-VDRIVIDDIEPSIFKAMLSFIYTDVLPN 259
           8**********************************999.************************9987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilk 29
           ++N+++ l++A++++  +Lk ++l+f+ +
   Q: 305  VDNVATTLALAEQHQFLQLKAFCLEFVAS 333
           69************************975 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Protein Sequence
(Fasta)

MSTVGGIEQL IPDSVSTSFI ETVNGSHQFT IQGYSLAKGM SPGKFIQSDI FSVGGYDWAI 60
YFYPDGKNPE DQSSYISLFI ALASDSNDIR ALFELTLMDQ SGKGKHKVHS HFDRALEGGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTATGGTCGT TGGACACTAC TTTCGAGCCC ATTACATTTA ATATCCTTTA AAATAAAAAA 60
TAAAGAAGGC GAAAACAGTT TCCCCCAAAT TCTCATAATT TTCACAAACA ACCTCTCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR034090--BPM_C
IPR000210--BTB/POZ_dom
IPR002083--MATH/TRAF_dom
IPR011333--SKP1/BTB/POZ
IPR008974--TRAF-like

PROSITE

PS50097--BTB
PS50144--MATH

Pfam

PF00651--BTB
PF00917--MATH

SMART

SM00225--BTB
SM00061--MATH

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0042802--F:identical protein binding
GO:0071472--P:cellular response to salt stress
GO:0016567--P:protein ubiquitination
GO:0031396--P:regulation of protein ubiquitination
GO:0006970--P:response to osmotic stress

KEGG

ath:AT2G39760

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002307	Ailuropoda melanoleuca	29.52	2.00e-36	146.00
IUUC-Atr-002874	Amborella trichopoda	62.11	2.00e-145	508.00
IUUC-Apl-003488	Anas platyrhynchos	30.33	5.00e-39	154.00
IUUC-Aca-005010	Anolis carolinensis	30.33	5.00e-39	154.00
IUUC-Aly-005813	Arabidopsis lyrata	97.00	0.00e+00	785.00
IUUC-Afu-009090	Aspergillus fumigatus	29.38	2.00e-11	63.50
IUUC-Ate-010432	Aspergillus terreus	29.38	3.00e-11	63.20
IUUC-Ame-011843	Astyanax mexicanus	30.89	3.00e-43	168.00
IUUC-Bta-013528	Bos taurus	32.51	3.00e-44	171.00
IUUC-Bdi-014327	Brachypodium distachyon	63.34	9.00e-133	466.00
IUUC-Bol-015178	Brassica oleracea	84.06	0.00e+00	688.00
IUUC-Bra-016833	Brassica rapa	85.38	0.00e+00	684.00
IUUC-Cel-018671	Caenorhabditis elegans	29.28	5.00e-36	144.00
IUUC-Cja-019227	Callithrix jacchus	31.68	1.00e-44	172.00
IUUC-Cfa-020115	Canis familiaris	30.05	2.00e-38	152.00
IUUC-Cpo-021660	Cavia porcellus	31.68	1.00e-44	172.00
IUUC-Cho-024732	Choloepus hoffmanni	35.41	1.00e-30	126.00
IUUC-Cin-025636	Ciona intestinalis	33.78	7.00e-46	177.00
IUUC-Csv-026167	Ciona savignyi	30.10	2.00e-38	152.00
IUUC-Dre-027880	Danio rerio	31.94	6.00e-45	174.00
IUUC-Dno-029399	Dasypus novemcinctus	31.15	5.00e-44	171.00
IUUC-Dor-030503	Dipodomys ordii	30.05	2.00e-38	152.00
IUUC-Dse-031195	Dothistroma septosporum	30.00	2.00e-12	67.40
IUUC-Dme-032218	Drosophila melanogaster	29.30	3.00e-34	139.00
IUUC-Ete-032328	Echinops telfairi	30.53	2.00e-38	152.00
IUUC-Eca-033238	Equus caballus	30.05	2.00e-38	152.00
IUUC-Eeu-035156	Erinaceus europaeus	32.52	5.00e-39	154.00
IUUC-Fca-035435	Felis catus	30.05	2.00e-38	152.00
IUUC-Fal-037023	Ficedula albicollis	31.15	1.00e-44	173.00
IUUC-Gmo-038600	Gadus morhua	30.33	6.00e-40	157.00
IUUC-Gga-040441	Gallus gallus	30.33	5.00e-39	154.00
IUUC-Gac-041911	Gasterosteus aculeatus	30.60	8.00e-40	157.00
IUUC-Gma-044082	Glycine max	66.24	2.00e-149	521.00
IUUC-Ggo-045160	Gorilla gorilla	31.68	1.00e-44	172.00
IUUC-Hsa-045729	Homo sapiens	31.68	1.00e-44	172.00
IUUC-Hvu-047528	Hordeum vulgare	62.76	2.00e-138	484.00
IUUC-Itr-048153	Ictidomys tridecemlineatus	31.41	2.00e-44	172.00
IUUC-Lch-050036	Latimeria chalumnae	29.92	1.00e-41	162.00
IUUC-Lpe-050732	Leersia perrieri	59.69	4.00e-134	470.00
IUUC-Loc-052374	Lepisosteus oculatus	30.60	2.00e-39	155.00
IUUC-Lma-053180	Leptosphaeria maculans	33.77	3.00e-05	43.10
IUUC-Laf-053691	Loxodonta africana	31.41	2.00e-44	172.00
IUUC-Mcc-055322	Macaca mulatta	30.05	2.00e-38	152.00
IUUC-Meu-056330	Macropus eugenii	26.50	3.00e-27	115.00
IUUC-Mga-059990	Meleagris gallopavo	31.15	1.00e-44	173.00
IUUC-Mmr-061748	Microcebus murinus	31.41	2.00e-44	172.00
IUUC-Mdo-062472	Monodelphis domestica	32.51	6.00e-45	174.00
IUUC-Mmu-064227	Mus musculus	30.05	2.00e-38	152.00
IUUC-Mac-064762	Musa acuminata	64.54	2.00e-134	471.00
IUUC-Mpu-065693	Mustela putorius furo	30.05	2.00e-38	152.00
IUUC-Mlu-067182	Myotis lucifugus	33.61	3.00e-43	168.00
IUUC-Nle-069115	Nomascus leucogenys	31.68	1.00e-44	172.00
IUUC-Opr-070490	Ochotona princeps	29.43	4.00e-37	148.00
IUUC-Ont-071726	Oreochromis niloticus	30.60	7.00e-40	157.00
IUUC-Oan-073449	Ornithorhynchus anatinus	30.63	9.00e-43	166.00
IUUC-Ocu-073817	Oryctolagus cuniculus	31.68	6.00e-45	174.00
IUUC-Oba-075571	Oryza barthii	62.17	1.00e-129	455.00
IUUC-Obr-076340	Oryza brachyantha	60.20	4.00e-132	463.00
IUUC-Ogl-077607	Oryza glaberrima	62.17	1.00e-129	455.00
IUUC-Ogu-078595	Oryza glumaepatula	62.17	1.00e-129	455.00
IUUC-Olo-080948	Oryza longistaminata	62.24	3.00e-129	454.00
IUUC-Oni-082973	Oryza nivara	62.17	1.00e-129	455.00
IUUC-Opu-084147	Oryza punctata	63.05	2.00e-133	468.00
IUUC-Oru-084463	Oryza rufipogon	62.17	1.00e-129	455.00
IUUC-Osa-085773	Oryza sativa	62.17	1.00e-129	455.00
IUUC-Ola-086989	Oryzias latipes	30.52	1.00e-38	153.00
IUUC-Oga-087982	Otolemur garnettii	32.51	1.00e-45	176.00
IUUC-Oar-089943	Ovis aries	30.56	2.00e-38	152.00
IUUC-Ptr-090729	Pan troglodytes	31.68	1.00e-44	172.00
IUUC-Pan-092504	Papio anubis	30.05	2.00e-38	152.00
IUUC-Psi-093063	Pelodiscus sinensis	30.33	5.00e-39	154.00
IUUC-Pma-094310	Petromyzon marinus	33.06	8.00e-42	163.00
IUUC-Pfo-096411	Poecilia formosa	30.60	7.00e-40	157.00
IUUC-Pab-098431	Pongo abelii	31.68	1.00e-44	172.00
IUUC-Pop-098825	Populus trichocarpa	73.46	6.00e-158	549.00
IUUC-Ppe-101816	Prunus persica	70.88	3.00e-153	533.00
IUUC-Pva-102660	Pteropus vampyrus	31.68	1.00e-42	166.00
IUUC-Rno-105399	Rattus norvegicus	30.05	2.00e-38	152.00
IUUC-Sha-106700	Sarcophilus harrisii	30.33	6.00e-39	154.00
IUUC-Sit-110513	Setaria italica	64.81	2.00e-136	478.00
IUUC-Sly-110886	Solanum lycopersicum	70.59	2.00e-135	474.00
IUUC-Stu-112678	Solanum tuberosum	70.59	2.00e-136	477.00
IUUC-Sar-113489	Sorex araneus	30.05	2.00e-38	152.00
IUUC-Sbi-114240	Sorghum bicolor	58.82	1.00e-135	475.00
IUUC-Ssc-116199	Sus scrofa	32.79	1.00e-44	172.00
IUUC-Tgu-116755	Taeniopygia guttata	31.32	1.00e-44	173.00
IUUC-Tru-117832	Takifugu rubripes	30.60	6.00e-40	157.00
IUUC-Tsy-118969	Tarsius syrichta	27.87	4.00e-32	131.00
IUUC-Tni-120221	Tetraodon nigroviridis	30.60	6.00e-40	157.00
IUUC-Tca-121666	Theobroma cacao	76.52	4.00e-157	546.00
IUUC-Tae-124631	Triticum aestivum	59.39	7.00e-139	486.00
IUUC-Tme-126982	Tuber melanosporum	35.80	9.00e-08	51.20
IUUC-Tbe-127298	Tupaia belangeri	29.51	1.00e-35	143.00
IUUC-Ttr-128952	Tursiops truncatus	30.05	2.00e-38	152.00
IUUC-Vvi-130854	Vitis vinifera	67.93	7.00e-143	499.00
IUUC-Xtr-132806	Xenopus tropicalis	32.79	2.00e-38	152.00
IUUC-Xma-134130	Xiphophorus maculatus	31.41	4.00e-44	171.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence