iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118448

UUCD1 version

UUC-TaR-00625

Ensembl Protein ID

ENSTRUP00000029563.1

UniProt Accession

H2TY04; H2TY04_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000011704.1	ENSTRUT00000029680.1	ENSTRUP00000029563.1
ENSTRUG00000011704.1	ENSTRUT00000029681.1	ENSTRUP00000029564.1
ENSTRUG00000011704.1	ENSTRUT00000029682.1	ENSTRUP00000029565.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.10e-16	60.3	35	102
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.20e-09	36.5	136	166

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalf.lmeleesksklmveikdvqpevfrallkFlYtgklden 68
           D++l+vg++ f++h++++aa+S++F+  f + + +e +++++v+++dv p  ++ ++k+lY+ ++d++
   Q: 35   DCTLKVGDRSFPCHRLIMAACSPYFREIFfTEDGKEVENTKEVVLEDVNPAILNMIIKYLYSAEIDLT 102
           9****************************6555558888**************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
            Nc++i+r++  ++cp+L+ aa+++i + F+
   Q: 136  GNCMAIFRLGLVLNCPRLAVAARNYIADRFE 166
           5***************************995 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

LAMDANAIKE ELRLFQSTLL QDGLKELLNE NKLVDCTLKV GDRSFPCHRL IMAACSPYFR 60
EIFFTEDGKE VENTKEVVLE DVNPAILNMI IKYLYSAEID LTDDNVQDII ALANRFQIPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGCCATGG ACGCCAACGC CATCAAGGAG GAGCTGCGCC TGTTTCAAAG TACCCTGCTC 60
CAGGATGGGC TGAAGGAGCT GCTGAATGAG AACAAGTTGG TGGACTGCAC GCTGAAGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0031430--C:M band
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cre-022766	Chlamydomonas reinhardtii	28.41	3.00e-07	48.90
IUUC-Csa-023184	Chlorocebus sabaeus	61.90	0.00e+00	673.00
IUUC-Dse-031465	Dothistroma septosporum	29.67	6.00e-06	45.10
IUUC-Gmo-039081	Gadus morhua	78.31	0.00e+00	842.00
IUUC-Gac-042252	Gasterosteus aculeatus	79.44	0.00e+00	998.00
IUUC-Ont-072420	Oreochromis niloticus	79.71	0.00e+00	997.00
IUUC-Ola-086361	Oryzias latipes	79.00	0.00e+00	944.00
IUUC-Pfo-096122	Poecilia formosa	79.51	0.00e+00	987.00
IUUC-Tni-120547	Tetraodon nigroviridis	87.40	0.00e+00	1052.00
IUUC-Xma-133860	Xiphophorus maculatus	80.16	0.00e+00	992.00
IUUC-Yli-134535	Yarrowia lipolytica	25.21	4.00e-08	52.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence