iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033339

Ensembl Protein ID

ENSECAP00000007705.1

UniProt Accession

F6Z6H5; F6Z6H5_HORSE

Protein Name

Uncharacterized protein

Gene Name

IFT80

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000009494.1	ENSECAT00000010029.1	ENSECAP00000007705.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-14	52.5	228	256

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+ ++t++a+ +d  l+++Gs  +t++++D
   Q: 228  HEHPITSVAWaPDgELFAVGS-FHTLRLCD 256
           99*********9978888887.689*9999 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MRLKISLLKE PKHQELVSCV GWTTAEELYS CSDDHQIVKW SLLTSETTQI VKLPDEIYPI 60
DLHWFPKSLG IKKQTQAENF VLTSSDGKFH LISKLGRVEK TVEAHCGAVL AGRWNYEGTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTGAATACA ATCAAGTGGC ATTTTAAAAT TTTGCTGGAA AGTGAAGACA TGAGACTGAA 60
GATATCTCTT TTAAAAGAAC CAAAGCATAT CCTTTTAATA CTTATAAACC TTATTATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0030992--C:intraciliary transport particle B
GO:0060349--P:bone morphogenesis
GO:0002062--P:chondrocyte differentiation
GO:0060271--P:cilium assembly
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:1905515--P:non-motile cilium assembly
GO:0001649--P:osteoblast differentiation
GO:0045880--P:positive regulation of smoothened signaling pathway
GO:0007224--P:smoothened signaling pathway

KEGG

ecb:100049959

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001564	Ailuropoda melanoleuca	96.61	0.00e+00	895.00
IUUC-Apl-003721	Anas platyrhynchos	85.31	0.00e+00	1374.00
IUUC-Aca-004488	Anolis carolinensis	85.54	0.00e+00	1389.00
IUUC-Ame-011402	Astyanax mexicanus	80.39	0.00e+00	814.00
IUUC-Bta-013037	Bos taurus	86.27	0.00e+00	1325.00
IUUC-Cel-018360	Caenorhabditis elegans	40.66	0.00e+00	662.00
IUUC-Cja-019076	Callithrix jacchus	91.99	0.00e+00	1207.00
IUUC-Cfa-020999	Canis familiaris	95.41	0.00e+00	1516.00
IUUC-Cpo-021333	Cavia porcellus	84.96	0.00e+00	1293.00
IUUC-Cre-022899	Chlamydomonas reinhardtii	47.14	0.00e+00	678.00
IUUC-Csa-023699	Chlorocebus sabaeus	94.76	0.00e+00	1503.00
IUUC-Cho-024904	Choloepus hoffmanni	87.39	0.00e+00	830.00
IUUC-Cin-025399	Ciona intestinalis	57.29	0.00e+00	958.00
IUUC-Csv-026186	Ciona savignyi	55.45	0.00e+00	927.00
IUUC-Dre-028276	Danio rerio	75.88	0.00e+00	1280.00
IUUC-Dno-029824	Dasypus novemcinctus	96.40	0.00e+00	1518.00
IUUC-Dor-031141	Dipodomys ordii	90.35	0.00e+00	1417.00
IUUC-Dme-031620	Drosophila melanogaster	35.83	1.00e-145	510.00
IUUC-Eeu-034909	Erinaceus europaeus	94.39	0.00e+00	999.00
IUUC-Fca-035780	Felis catus	95.82	0.00e+00	1491.00
IUUC-Fal-037447	Ficedula albicollis	78.86	0.00e+00	1266.00
IUUC-Gmo-038657	Gadus morhua	61.16	0.00e+00	828.00
IUUC-Gga-040689	Gallus gallus	85.79	0.00e+00	1382.00
IUUC-Gac-041586	Gasterosteus aculeatus	73.38	0.00e+00	1016.00
IUUC-Hsa-047005	Homo sapiens	94.85	0.00e+00	1526.00
IUUC-Itr-048757	Ictidomys tridecemlineatus	97.15	0.00e+00	1118.00
IUUC-Lch-050459	Latimeria chalumnae	82.10	0.00e+00	1328.00
IUUC-Loc-052774	Lepisosteus oculatus	78.57	0.00e+00	1062.00
IUUC-Laf-053765	Loxodonta africana	94.69	0.00e+00	1459.00
IUUC-Mcc-055052	Macaca mulatta	94.76	0.00e+00	1503.00
IUUC-Meu-056368	Macropus eugenii	81.13	0.00e+00	1266.00
IUUC-Mga-059488	Meleagris gallopavo	85.68	0.00e+00	1381.00
IUUC-Mmr-061527	Microcebus murinus	94.89	0.00e+00	1491.00
IUUC-Mdo-062850	Monodelphis domestica	93.98	0.00e+00	1211.00
IUUC-Mmu-063117	Mus musculus	94.34	0.00e+00	1498.00
IUUC-Mpu-066550	Mustela putorius furo	96.38	0.00e+00	1382.00
IUUC-Mlu-067772	Myotis lucifugus	91.60	0.00e+00	1401.00
IUUC-Nle-069215	Nomascus leucogenys	93.94	0.00e+00	1512.00
IUUC-Opr-070725	Ochotona princeps	72.91	0.00e+00	1101.00
IUUC-Ont-072147	Oreochromis niloticus	74.05	0.00e+00	1257.00
IUUC-Oan-073176	Ornithorhynchus anatinus	87.10	3.00e-62	229.00
IUUC-Ocu-073896	Oryctolagus cuniculus	94.44	0.00e+00	1213.00
IUUC-Ola-086767	Oryzias latipes	68.91	0.00e+00	957.00
IUUC-Oga-088113	Otolemur garnettii	94.43	0.00e+00	1519.00
IUUC-Oar-089683	Ovis aries	91.67	0.00e+00	1448.00
IUUC-Ptr-091563	Pan troglodytes	95.54	0.00e+00	1525.00
IUUC-Pan-092042	Papio anubis	94.76	0.00e+00	1503.00
IUUC-Psi-093306	Pelodiscus sinensis	87.55	0.00e+00	1444.00
IUUC-Ppa-095694	Physcomitrella patens	44.53	0.00e+00	716.00
IUUC-Pfo-096800	Poecilia formosa	72.40	0.00e+00	1236.00
IUUC-Pab-098356	Pongo abelii	94.72	0.00e+00	1523.00
IUUC-Pva-102246	Pteropus vampyrus	90.78	0.00e+00	1409.00
IUUC-Rno-105195	Rattus norvegicus	94.59	0.00e+00	1499.00
IUUC-Sha-107056	Sarcophilus harrisii	93.85	0.00e+00	1488.00
IUUC-Smo-109240	Selaginella moellendorffii	43.73	2.00e-175	608.00
IUUC-Sar-113301	Sorex araneus	86.39	4.00e-150	525.00
IUUC-Ssc-116040	Sus scrofa	95.67	6.00e-146	509.00
IUUC-Tgu-117127	Taeniopygia guttata	80.75	0.00e+00	1315.00
IUUC-Tru-118663	Takifugu rubripes	70.55	0.00e+00	1195.00
IUUC-Tsy-119207	Tarsius syrichta	83.40	0.00e+00	1305.00
IUUC-Tni-120705	Tetraodon nigroviridis	69.41	0.00e+00	1183.00
IUUC-Tbe-127434	Tupaia belangeri	86.28	0.00e+00	950.00
IUUC-Ttr-128937	Tursiops truncatus	95.62	0.00e+00	1517.00
IUUC-Vpa-130518	Vicugna pacos	90.73	0.00e+00	1400.00
IUUC-Xtr-131879	Xenopus tropicalis	77.06	0.00e+00	1274.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence