iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118230

UUCD1 version

UUC-TaR-00571

Ensembl Protein ID

ENSTRUP00000027468.1

UniProt Accession

H2TS10; H2TS10_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000010869.1	ENSTRUT00000027577.1	ENSTRUP00000027468.1
ENSTRUG00000010869.1	ENSTRUT00000027578.1	ENSTRUP00000027469.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.50e-33	117.3	95	262

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseyl....qkesdffsefieek........edekefcqklvepeakg 77
           ++l t+gDGnCLl+A+sq++lgv+d+d+ l++ l+ +L+e+ +  +    q e  + +ef +++        e+e++ + k+++p + +
   Q: 95   VPLRTNGDGNCLLHATSQYMLGVQDTDLvLRKTLHGVLKETDTGVFrarfQAELIQSQEFTQTGlryttmnwEEEWDKIVKMASPVSSS 183
           6789***************************************9998888888889999999999*******************99765 PP
   S: 78   ........eeihifaLaqiLsrpiivvdvdsles..........kvggillpllfpeek.lkkpivLlYrsgHYdaLva 137
                   e ihif+L++iL+rpiiv++++ ++s          +vggi+lpl++p+ + +k+pivL+Y+s H+ +L++
   Q: 184  nglqfdslEDIHIFILSNILRRPIIVIADQVVRSmksgssisplNVGGIYLPLHWPPTEcYKYPIVLGYDSQHFAPLIT 262
           56*******************************9******************************************975 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

QGQNFLPKFL FVSNLLKAVK IRQRVPNDVV KPANGSGLIH HLRGMHRYTL EMIAMNHFPQ 60
AFREVVQAAI LDRAMQATLE QEKKLNWCRE VKKMVPLRTN GDGNCLLHAT SQYMLGVQDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGTCAGA ACTTCCTGCC CAAATTCCTG TTTGTCTCCA ACCTTCTGAA GGCCGTGAAG 60
ATCCGGCAAC GTGTGCCCAA CGATGTGGTG AAGCCGGCCA ACGGCAGCGG CCTGATACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033478--A20
IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

SMART

SM00259--ZnF_A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006955--P:immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0016567--P:protein ubiquitination
GO:0050727--P:regulation of inflammatory response
GO:0045088--P:regulation of innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001825	Ailuropoda melanoleuca	47.41	0.00e+00	733.00
IUUC-Apl-003501	Anas platyrhynchos	48.89	0.00e+00	727.00
IUUC-Aca-004245	Anolis carolinensis	46.79	0.00e+00	728.00
IUUC-Ame-011789	Astyanax mexicanus	72.22	0.00e+00	1118.00
IUUC-Bta-012664	Bos taurus	48.63	0.00e+00	737.00
IUUC-Cja-019895	Callithrix jacchus	46.88	0.00e+00	730.00
IUUC-Cfa-020754	Canis familiaris	47.73	0.00e+00	734.00
IUUC-Cpo-021780	Cavia porcellus	47.17	0.00e+00	731.00
IUUC-Csa-023568	Chlorocebus sabaeus	47.17	0.00e+00	734.00
IUUC-Cho-024300	Choloepus hoffmanni	59.29	9.00e-124	437.00
IUUC-Dre-028577	Danio rerio	74.91	0.00e+00	1132.00
IUUC-Dno-029382	Dasypus novemcinctus	48.51	0.00e+00	729.00
IUUC-Dor-030874	Dipodomys ordii	46.00	0.00e+00	700.00
IUUC-Ete-032721	Echinops telfairi	58.31	3.00e-147	515.00
IUUC-Eca-033596	Equus caballus	46.86	0.00e+00	711.00
IUUC-Eeu-035159	Erinaceus europaeus	44.02	1.00e-146	513.00
IUUC-Fca-035847	Felis catus	47.16	0.00e+00	727.00
IUUC-Fal-036681	Ficedula albicollis	47.29	0.00e+00	720.00
IUUC-Gmo-038521	Gadus morhua	91.85	0.00e+00	749.00
IUUC-Gga-040975	Gallus gallus	46.83	0.00e+00	731.00
IUUC-Gac-042216	Gasterosteus aculeatus	86.47	0.00e+00	1251.00
IUUC-Ggo-045258	Gorilla gorilla	47.10	0.00e+00	733.00
IUUC-Hsa-046071	Homo sapiens	47.23	0.00e+00	736.00
IUUC-Itr-048386	Ictidomys tridecemlineatus	47.04	0.00e+00	732.00
IUUC-Lch-050326	Latimeria chalumnae	50.81	0.00e+00	781.00
IUUC-Loc-051945	Lepisosteus oculatus	56.56	0.00e+00	792.00
IUUC-Laf-053722	Loxodonta africana	46.99	0.00e+00	728.00
IUUC-Mcc-055503	Macaca mulatta	47.05	0.00e+00	734.00
IUUC-Meu-056481	Macropus eugenii	44.56	0.00e+00	642.00
IUUC-Mga-059690	Meleagris gallopavo	45.23	0.00e+00	656.00
IUUC-Mmr-061233	Microcebus murinus	46.91	0.00e+00	730.00
IUUC-Mdo-062446	Monodelphis domestica	47.41	0.00e+00	721.00
IUUC-Mmu-063436	Mus musculus	46.61	0.00e+00	719.00
IUUC-Mpu-066808	Mustela putorius furo	47.52	0.00e+00	741.00
IUUC-Mlu-067339	Myotis lucifugus	47.17	0.00e+00	731.00
IUUC-Nle-069888	Nomascus leucogenys	46.98	0.00e+00	732.00
IUUC-Opr-070303	Ochotona princeps	46.38	0.00e+00	723.00
IUUC-Ont-072283	Oreochromis niloticus	84.60	0.00e+00	1307.00
IUUC-Oan-072925	Ornithorhynchus anatinus	49.26	0.00e+00	762.00
IUUC-Ocu-073889	Oryctolagus cuniculus	47.36	0.00e+00	729.00
IUUC-Ola-087417	Oryzias latipes	85.36	0.00e+00	1266.00
IUUC-Oga-088708	Otolemur garnettii	46.29	0.00e+00	696.00
IUUC-Oar-089271	Ovis aries	48.64	0.00e+00	745.00
IUUC-Ptr-091296	Pan troglodytes	47.23	0.00e+00	736.00
IUUC-Pan-092474	Papio anubis	47.05	0.00e+00	733.00
IUUC-Psi-093447	Pelodiscus sinensis	48.32	0.00e+00	737.00
IUUC-Pfo-096511	Poecilia formosa	84.57	0.00e+00	1282.00
IUUC-Pab-098700	Pongo abelii	46.98	0.00e+00	731.00
IUUC-Pca-100246	Procavia capensis	45.45	2.00e-136	479.00
IUUC-Pva-102606	Pteropus vampyrus	48.85	1.00e-109	390.00
IUUC-Rno-105818	Rattus norvegicus	46.72	0.00e+00	721.00
IUUC-Sha-106559	Sarcophilus harrisii	46.57	0.00e+00	721.00
IUUC-Sar-113454	Sorex araneus	62.31	1.00e-126	447.00
IUUC-Ssc-116064	Sus scrofa	48.34	0.00e+00	741.00
IUUC-Tgu-117212	Taeniopygia guttata	47.52	0.00e+00	712.00
IUUC-Tsy-119066	Tarsius syrichta	47.37	0.00e+00	736.00
IUUC-Tni-119825	Tetraodon nigroviridis	91.83	0.00e+00	1378.00
IUUC-Tbe-127601	Tupaia belangeri	62.31	1.00e-125	443.00
IUUC-Ttr-128930	Tursiops truncatus	48.03	0.00e+00	732.00
IUUC-Vpa-130450	Vicugna pacos	59.80	2.00e-144	506.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence