iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004988

Ensembl Protein ID

ENSACAP00000009332.2

UniProt Accession

H9GFB2; H9GFB2_ANOCA

Protein Name

Uncharacterized protein

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000009401.2	ENSACAT00000009527.2	ENSACAP00000009332.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.60e-15	55.0	165	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ + ++ +n+deL+++kGdv+ v     +++gW++g  +l+gk G fP+n+v++++
   Q: 165  VVRARFHFKQTNEDELSINKGDVICVT--RVEEGGWWEG--TLNGKTGWFPSNYVKEIK 219
           68999*********************7..999*******..8**************996 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MNPEEQIVTW LISLGALNSP KMKVGDPLQF LKTSLKDGVV LCKLLLRLLP GSIEKHCPEP 60
KTEADCVGNI KAFLSGCAAL KVELFDAHDL YAGDNFPQVL NTLAAICKAT EDQPSARPCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAACCCCG AAGAGCAAAT TGTGACCTGG TTGATTTCAT TGGGAGCCTT AAACTCCCCG 60
AAAATGAAGG TCGGGGACCC TCTGCAGTTC CTCAAAACAT CCCTCAAAGA CGGAGTCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	62.30	0.00e+00	967.00
IUUC-Apl-003960	Anas platyrhynchos	80.05	0.00e+00	1197.00
IUUC-Ame-011546	Astyanax mexicanus	65.17	0.00e+00	924.00
IUUC-Bta-013527	Bos taurus	70.57	0.00e+00	1045.00
IUUC-Cja-018935	Callithrix jacchus	70.04	0.00e+00	1033.00
IUUC-Cfa-021269	Canis familiaris	70.51	0.00e+00	1044.00
IUUC-Cpo-021620	Cavia porcellus	67.43	0.00e+00	994.00
IUUC-Csa-023415	Chlorocebus sabaeus	70.44	0.00e+00	1046.00
IUUC-Cne-026866	Cryptococcus neoformans	52.94	9.00e-13	69.70
IUUC-Dre-028580	Danio rerio	64.33	0.00e+00	937.00
IUUC-Dno-029201	Dasypus novemcinctus	66.67	0.00e+00	1008.00
IUUC-Dor-030868	Dipodomys ordii	58.35	0.00e+00	769.00
IUUC-Eca-033500	Equus caballus	70.18	0.00e+00	1031.00
IUUC-Eeu-035269	Erinaceus europaeus	59.83	4.00e-115	408.00
IUUC-Fca-035683	Felis catus	70.31	0.00e+00	1029.00
IUUC-Fal-037611	Ficedula albicollis	80.18	0.00e+00	1196.00
IUUC-Gmo-038980	Gadus morhua	60.68	0.00e+00	866.00
IUUC-Gga-040940	Gallus gallus	78.89	0.00e+00	1178.00
IUUC-Gac-042203	Gasterosteus aculeatus	60.82	0.00e+00	899.00
IUUC-Ggo-044755	Gorilla gorilla	70.29	0.00e+00	1038.00
IUUC-Hsa-046210	Homo sapiens	70.04	0.00e+00	1036.00
IUUC-Lch-049517	Latimeria chalumnae	70.68	0.00e+00	1025.00
IUUC-Loc-052393	Lepisosteus oculatus	65.31	0.00e+00	983.00
IUUC-Laf-054196	Loxodonta africana	70.14	0.00e+00	1012.00
IUUC-Mcc-055716	Macaca mulatta	70.31	0.00e+00	1044.00
IUUC-Meu-056285	Macropus eugenii	62.66	1.00e-159	556.00
IUUC-Mtr-058576	Medicago truncatula	40.26	6.00e-11	61.20
IUUC-Mla-059044	Melampsora laricipopulina	26.58	2.00e-18	88.20
IUUC-Mga-060029	Meleagris gallopavo	79.67	0.00e+00	1203.00
IUUC-Mmr-060803	Microcebus murinus	70.82	0.00e+00	1043.00
IUUC-Mdo-062654	Monodelphis domestica	72.16	0.00e+00	1063.00
IUUC-Mmu-063479	Mus musculus	68.77	0.00e+00	1011.00
IUUC-Mpu-066065	Mustela putorius furo	69.49	0.00e+00	1012.00
IUUC-Mlu-068222	Myotis lucifugus	68.93	0.00e+00	1004.00
IUUC-Nle-069379	Nomascus leucogenys	70.29	0.00e+00	1038.00
IUUC-Oan-073067	Ornithorhynchus anatinus	76.22	0.00e+00	1143.00
IUUC-Ocu-074852	Oryctolagus cuniculus	69.28	0.00e+00	1019.00
IUUC-Oar-089339	Ovis aries	70.31	0.00e+00	1041.00
IUUC-Pan-092666	Papio anubis	68.72	0.00e+00	1002.00
IUUC-Psi-093116	Pelodiscus sinensis	80.03	0.00e+00	1211.00
IUUC-Pfo-097394	Poecilia formosa	63.25	0.00e+00	932.00
IUUC-Pab-098567	Pongo abelii	70.29	0.00e+00	1039.00
IUUC-Pca-100997	Procavia capensis	61.00	0.00e+00	834.00
IUUC-Pva-102500	Pteropus vampyrus	68.89	0.00e+00	995.00
IUUC-Rno-104974	Rattus norvegicus	69.15	0.00e+00	995.00
IUUC-Sly-111123	Solanum lycopersicum	46.67	4.00e-09	55.50
IUUC-Stu-112434	Solanum tuberosum	46.67	4.00e-09	55.50
IUUC-Sar-113420	Sorex araneus	67.35	0.00e+00	970.00
IUUC-Ssc-115679	Sus scrofa	70.61	0.00e+00	928.00
IUUC-Tgu-117069	Taeniopygia guttata	79.33	0.00e+00	1182.00
IUUC-Tsy-119243	Tarsius syrichta	65.42	0.00e+00	728.00
IUUC-Tni-120584	Tetraodon nigroviridis	61.67	0.00e+00	892.00
IUUC-Tbe-127994	Tupaia belangeri	57.58	0.00e+00	829.00
IUUC-Ttr-128839	Tursiops truncatus	69.28	0.00e+00	1004.00
IUUC-Xtr-132624	Xenopus tropicalis	70.50	0.00e+00	1064.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence