iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tvi-122275

Ensembl Protein ID

EHK17418

UniProt Accession

G9N6R7; G9N6R7_HYPVG

Genbank Protein ID

EHK17418.1

Protein Name

Lactoylglutathione lyase; Glyoxalase I

Genbank Nucleotide ID

ABDF02000088

Gene Name

TRIVIDRAFT_82911

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIVIDRAFT_82911	EHK17418	EHK17418

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	35.90	9.70e-02	28.90	IUUC-Ots-000007

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Trichoderma virens

Functional Description
(View)

Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

Protein Sequence
(Fasta)

MAATTDLNTY KFNHSMIRVK DPKESVKFYE FLGMSVIRKV EFPEAKFDLY FMGYNSKGAI 60
SCGNSPIDRE GVIELTHNYG TENDPTYTIN NGNKDPHRGF GHTCISVDNI QAACQRIEDA 120

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Nucleotide Sequence
(Fasta)

CGAATCTCGG AAAAAAATTG CTGGAATTAT TTCTCATATA CAGCGACAGC ATCTCCTTTG 60
TGATCAAGGA GATCCTCCTC TGTCTTCATC ATTCTACTCA AATCTCTGCA TTGTTTACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0456--Lyase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR029068--Glyas_Bleomycin-R_OHBP_Dase
IPR004360--Glyas_Fos-R_dOase_dom
IPR004361--Glyoxalase_1
IPR018146--Glyoxalase_1_CS

PROSITE

PS00934--GLYOXALASE_I_1
PS00935--GLYOXALASE_I_2

Pfam

PF00903--Glyoxalase

Gene Ontology

GO:0004462--F:lactoylglutathione lyase activity
GO:0046872--F:metal ion binding
GO:0006749--P:glutathione metabolic process
GO:0019243--P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bra-017733	Brassica rapa	58.82	2.40e+00	26.20
IUUC-Mga-059442	Meleagris gallopavo	28.12	2.40e-01	28.90
IUUC-Mmu-063159	Mus musculus	30.23	3.70e-01	28.50
IUUC-Psi-093100	Pelodiscus sinensis	24.83	1.50e+00	26.20
IUUC-Pfo-136642	Poecilia formosa	30.61	7.80e-01	27.30
IUUC-Pop-099481	Populus trichocarpa	69.23	3.60e+00	24.30
IUUC-Tme-127218	Tuber melanosporum	61.23	1.00e-101	360.00
IUUC-Xma-136739	Xiphophorus maculatus	30.61	1.10e+00	26.90

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence