iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091350

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03125998

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000014211.5	ENSPTRT00000026547.5	ENSPTRP00000024465.5

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.43	0.00e+00	1552.00	IUUC-Hsa-046484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MRPRSGGRPG APGRRHRRLR RRPRGLRCSR LPPPPPLPLL LGLLLAAAGP GAARAKETAF 60
VEVVLFESSP SGDYTTYTTG LTGRFSRAGA TLSAEGEIVQ MHPLGLCNNN DEEDLYEYGW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCCGC GCTCGGGCGG GCGCCCAGGG GCCCCGGGCC GCCGCCACCG CCGCCTGCGC 60
CGCCGCCCCC GCGGCCTCCG GTGCAGCCGC CTGCCGCCGC CGCCGCCGCT GCCGCTGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	86.79	0.00e+00	1230.00
IUUC-Apl-004188	Anas platyrhynchos	71.24	0.00e+00	1048.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	4.00e-15	73.60
IUUC-Ath-007372	Arabidopsis thaliana	42.68	2.00e-14	71.60
IUUC-Ame-011764	Astyanax mexicanus	62.15	0.00e+00	728.00
IUUC-Bta-012478	Bos taurus	66.58	0.00e+00	653.00
IUUC-Bol-016217	Brassica oleracea	56.25	3.00e-14	70.90
IUUC-Bra-017407	Brassica rapa	56.25	3.00e-14	70.90
IUUC-Cja-019504	Callithrix jacchus	95.33	0.00e+00	1460.00
IUUC-Cfa-020048	Canis familiaris	88.96	0.00e+00	1332.00
IUUC-Cpo-021725	Cavia porcellus	82.87	0.00e+00	1265.00
IUUC-Csa-023586	Chlorocebus sabaeus	96.44	0.00e+00	1426.00
IUUC-Cho-024867	Choloepus hoffmanni	91.94	0.00e+00	689.00
IUUC-Cin-025569	Ciona intestinalis	47.33	3.00e-56	213.00
IUUC-Csv-025869	Ciona savignyi	45.33	2.00e-57	216.00
IUUC-Dre-027553	Danio rerio	66.21	0.00e+00	856.00
IUUC-Dno-029370	Dasypus novemcinctus	84.65	0.00e+00	1215.00
IUUC-Dor-030816	Dipodomys ordii	81.49	0.00e+00	1138.00
IUUC-Ete-033060	Echinops telfairi	75.27	0.00e+00	849.00
IUUC-Eca-034044	Equus caballus	88.71	0.00e+00	1323.00
IUUC-Eeu-034591	Erinaceus europaeus	68.09	1.00e-138	486.00
IUUC-Fca-036000	Felis catus	87.84	0.00e+00	1325.00
IUUC-Fal-037147	Ficedula albicollis	70.92	0.00e+00	1061.00
IUUC-Gmo-039099	Gadus morhua	50.43	3.00e-119	421.00
IUUC-Ggr-039947	Gaeumannomyces graminis	30.43	3.00e-11	63.20
IUUC-Gga-041243	Gallus gallus	67.86	0.00e+00	835.00
IUUC-Gac-041340	Gasterosteus aculeatus	49.23	2.00e-114	405.00
IUUC-Gma-044387	Glycine max	50.00	4.00e-15	74.30
IUUC-Ggo-044953	Gorilla gorilla	98.57	0.00e+00	1471.00
IUUC-Hsa-046484	Homo sapiens	99.43	0.00e+00	1550.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	88.74	0.00e+00	1305.00
IUUC-Lch-050004	Latimeria chalumnae	58.85	0.00e+00	673.00
IUUC-Loc-051830	Lepisosteus oculatus	65.19	0.00e+00	837.00
IUUC-Laf-053975	Loxodonta africana	85.84	0.00e+00	1263.00
IUUC-Mcc-055302	Macaca mulatta	95.97	0.00e+00	1390.00
IUUC-Meu-056263	Macropus eugenii	75.23	0.00e+00	794.00
IUUC-Mtr-058744	Medicago truncatula	54.17	2.00e-13	68.60
IUUC-Mga-059706	Meleagris gallopavo	71.23	0.00e+00	1068.00
IUUC-Mmr-061372	Microcebus murinus	89.33	0.00e+00	1279.00
IUUC-Mdo-062651	Monodelphis domestica	65.43	0.00e+00	870.00
IUUC-Mmu-064339	Mus musculus	84.88	0.00e+00	1314.00
IUUC-Mac-065356	Musa acuminata	50.00	9.00e-13	67.80
IUUC-Mpu-066211	Mustela putorius furo	86.65	0.00e+00	1276.00
IUUC-Mlu-067058	Myotis lucifugus	88.19	0.00e+00	1248.00
IUUC-Nle-069886	Nomascus leucogenys	98.30	0.00e+00	1446.00
IUUC-Opr-070218	Ochotona princeps	82.28	0.00e+00	1107.00
IUUC-Ont-072483	Oreochromis niloticus	62.50	0.00e+00	828.00
IUUC-Oan-073718	Ornithorhynchus anatinus	71.04	0.00e+00	923.00
IUUC-Ocu-073847	Oryctolagus cuniculus	80.54	0.00e+00	1067.00
IUUC-Oba-075528	Oryza barthii	43.64	3.00e-12	66.20
IUUC-Obr-076184	Oryza brachyantha	53.33	2.00e-12	67.00
IUUC-Opu-083306	Oryza punctata	67.44	6.00e-13	67.40
IUUC-Ola-087358	Oryzias latipes	61.90	0.00e+00	765.00
IUUC-Oga-088362	Otolemur garnettii	87.92	0.00e+00	1337.00
IUUC-Oar-090197	Ovis aries	99.49	9.00e-97	347.00
IUUC-Pan-091700	Papio anubis	96.17	0.00e+00	1446.00
IUUC-Psi-093301	Pelodiscus sinensis	69.25	0.00e+00	990.00
IUUC-Pfo-096917	Poecilia formosa	63.33	0.00e+00	765.00
IUUC-Pab-097932	Pongo abelii	97.38	0.00e+00	1485.00
IUUC-Pop-099640	Populus trichocarpa	57.14	1.00e-14	72.80
IUUC-Pca-101054	Procavia capensis	93.21	0.00e+00	966.00
IUUC-Pva-102879	Pteropus vampyrus	89.25	0.00e+00	1342.00
IUUC-Pgr-103476	Puccinia graminis	41.27	2.00e-09	56.20
IUUC-Sha-106507	Sarcophilus harrisii	54.16	1.00e-164	573.00
IUUC-Sit-110656	Setaria italica	67.44	5.00e-13	67.00
IUUC-Stu-112500	Solanum tuberosum	62.79	7.00e-13	66.60
IUUC-Sar-113182	Sorex araneus	82.33	4.00e-112	399.00
IUUC-Sbi-114414	Sorghum bicolor	40.00	1.00e-12	65.90
IUUC-Ssc-115966	Sus scrofa	81.05	0.00e+00	1077.00
IUUC-Tgu-116864	Taeniopygia guttata	63.33	0.00e+00	682.00
IUUC-Tru-118502	Takifugu rubripes	62.93	0.00e+00	798.00
IUUC-Tsy-119210	Tarsius syrichta	89.47	0.00e+00	1295.00
IUUC-Tni-120344	Tetraodon nigroviridis	52.57	6.00e-123	434.00
IUUC-Tca-120966	Theobroma cacao	48.39	3.00e-13	69.30
IUUC-Tur-125977	Triticum urartu	50.00	2.00e-13	70.10
IUUC-Tbe-127735	Tupaia belangeri	87.46	1.00e-136	480.00
IUUC-Ttr-128714	Tursiops truncatus	76.07	0.00e+00	1002.00
IUUC-Vvi-131280	Vitis vinifera	31.50	3.00e-13	69.30
IUUC-Xtr-132280	Xenopus tropicalis	59.25	0.00e+00	759.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence