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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-104834
Ensembl Protein ID ENSRNOP00000073503.1
UniProt Accession B5DEL1; KCTD5_RAT
Genbank Protein ID EDM03804.1; AAI68712.1
Protein Name BTB/POZ domain-containing protein KCTD5
Genbank Nucleotide ID CH473948; BC168712
Gene Name Kctd5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000057186.1 ENSRNOT00000084991.1 ENSRNOP00000073503.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFACRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 3.70e-11 43.6 44 114
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaas.SsvFyalf..lmele.esksklmveikdvqpevfrallkFlYtgklden 68
           ++v l+vgg++f +++ +L++   s++y+l+  + +l+ ++++++ + i+ ++p++f  +l++l++gkl +n
   Q: 44   KWVRLNVGGTYFLTTRQTLCRDpKSFLYRLCqaDPDLDsDKDETGAYLID-RDPTYFGPVLNYLRHGKLVIN 114
           59*****************************7777777788999999**9.******************887 PP
   
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (By similarity).
 Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (By similarity).
Protein Sequence
(Fasta)
MAENHCELLP PAPSGLGAGL GGGLCRRCSA GIGALAQRPS GVSKWVRLNV GGTYFLTTRQ 60
TLCRDPKSFL YRLCQADPDL DSDKDETGAY LIDRDPTYFG PVLNYLRHGK LVINRDLAEE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-104834|E3,BTB_Other|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGGCTTGTT AGGATCATGG CGGAGAATCA CTGCGAGCTG CTACCGCCGG CTCCGAGCGG 60
CCTCGGGGCG GGGCTGGGGG GCGGCCTGTG CCGCCGCTGC AGCGCTGGGA TCGGCGCCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-104834|E3,BTB_Other|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome
Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR003131--T1-type_BTB
Pfam

PF02214--BTB_2
SMART

SM00225--BTB
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0097602--F:cullin family protein binding
GO:0032403--F:protein complex binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization
KEGG rno:287109
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aca-005071 Anolis carolinensis 96.34 7.00e-109 386.00
IUUC-Ame-011953 Astyanax mexicanus 66.09 8.00e-86 309.00
IUUC-Bta-013238 Bos taurus 94.87 5.00e-115 406.00
IUUC-Cfa-020368 Canis familiaris 96.15 3.00e-124 437.00
IUUC-Cpo-022539 Cavia porcellus 95.73 3.00e-123 434.00
IUUC-Cho-024408 Choloepus hoffmanni 75.68 3.00e-62 230.00
IUUC-Csv-026375 Ciona savignyi 72.40 2.00e-83 301.00
IUUC-Dre-027599 Danio rerio 90.05 3.00e-102 363.00
IUUC-Dno-029324 Dasypus novemcinctus 94.02 6.00e-113 399.00
IUUC-Dor-030398 Dipodomys ordii 83.76 1.00e-105 375.00
IUUC-Dme-031661 Drosophila melanogaster 62.94 4.00e-66 243.00
IUUC-Eca-033240 Equus caballus 85.04 8.00e-113 399.00
IUUC-Fal-037455 Ficedula albicollis 89.76 7.00e-107 379.00
IUUC-Gmo-039650 Gadus morhua 86.50 1.00e-100 358.00
IUUC-Gga-040799 Gallus gallus 74.56 3.00e-92 331.00
IUUC-Gac-042357 Gasterosteus aculeatus 80.93 2.00e-107 381.00
IUUC-Ggo-044563 Gorilla gorilla 95.73 4.00e-120 423.00
IUUC-Hsa-045899 Homo sapiens 95.73 4.00e-120 423.00
IUUC-Laf-053631 Loxodonta africana 90.60 4.00e-121 426.00
IUUC-Mcc-055489 Macaca mulatta 96.36 2.00e-109 387.00
IUUC-Mga-059269 Meleagris gallopavo 91.88 2.00e-83 300.00
IUUC-Mmr-061170 Microcebus murinus 96.90 4.00e-113 400.00
IUUC-Mdo-063068 Monodelphis domestica 87.29 3.00e-112 397.00
IUUC-Mmu-064160 Mus musculus 98.29 3.00e-120 423.00
IUUC-Mpu-066707 Mustela putorius furo 94.44 7.00e-124 436.00
IUUC-Mlu-067096 Myotis lucifugus 95.30 2.00e-117 414.00
IUUC-Ont-072315 Oreochromis niloticus 89.95 6.00e-110 389.00
IUUC-Oan-072751 Ornithorhynchus anatinus 94.70 2.00e-84 304.00
IUUC-Ocu-074090 Oryctolagus cuniculus 97.01 5.00e-117 413.00
IUUC-Ola-087038 Oryzias latipes 86.19 2.00e-105 374.00
IUUC-Oga-088148 Otolemur garnettii 95.73 8.00e-117 412.00
IUUC-Oar-089499 Ovis aries 97.40 2.00e-92 330.00
IUUC-Pan-092829 Papio anubis 96.58 7.00e-118 416.00
IUUC-Ppa-095886 Physcomitrella patens 34.82 2.00e-11 62.00
IUUC-Pfo-097467 Poecilia formosa 70.63 4.00e-95 340.00
IUUC-Pab-098083 Pongo abelii 81.20 2.00e-89 320.00
IUUC-Smo-109623 Selaginella moellendorffii 36.59 1.00e-12 67.80
IUUC-Tgu-116616 Taeniopygia guttata 95.70 1.00e-104 371.00
IUUC-Tru-118495 Takifugu rubripes 89.47 2.00e-110 390.00
IUUC-Tni-120558 Tetraodon nigroviridis 88.52 2.00e-109 387.00
IUUC-Ttr-129255 Tursiops truncatus 95.30 5.00e-124 436.00
IUUC-Xtr-132856 Xenopus tropicalis 85.09 3.00e-108 384.00
Created Date 25-Jun-2017

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