iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025605

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

EAAA01000384

Gene Name

LOC100184799

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000022729.1	ENSCINT00000036132.1	ENSCINP00000031420.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.40e-14	51.7	54	114

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk....elegkrGlfPenFvek 61
           +e++++lydy+a + d+L+++kGd+++++  +   ++W+k+      +++  +G++P+n+v+k
   Q: 54   EEVFIALYDYNARTADDLSFRKGDTLYIL--DRSQGDWWKARLltqnQTNSWEGFVPSNYVAK 114
           6889*************************..88999*****88888899999*********97 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MGFCWSKFLS CIGRNVSSDE NESVHSPNEF HNIRKTVQIH TIPDRPAPML PHNEEVFIAL 60
YDYNARTADD LSFRKGDTLY ILDRSQGDWW KARLLTQNQT NSWEGFVPSN YVAKYSSLDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAATTCGTT TTAAATTTGG TTGAGACGAA ACAGGACCGT ACTGCAACAA TTTGGATACG 60
ATACCCTGTG TATGCTTCCA TCGAAGCTGA ATAAATTCTC AAGCTATTCA AAGTGAGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

cin:100184799

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000140	Aegilops tauschii	28.09	1.00e-20	94.00
IUUC-Atr-002778	Amborella trichopoda	28.41	3.00e-22	99.40
IUUC-Aca-004553	Anolis carolinensis	55.22	5.00e-152	529.00
IUUC-Bdi-014122	Brachypodium distachyon	29.12	9.00e-22	97.40
IUUC-Bra-017486	Brassica rapa	29.00	1.00e-20	94.00
IUUC-Cel-018682	Caenorhabditis elegans	55.90	4.00e-153	533.00
IUUC-Cja-019885	Callithrix jacchus	55.34	5.00e-154	536.00
IUUC-Csv-026198	Ciona savignyi	66.81	0.00e+00	645.00
IUUC-Dre-028274	Danio rerio	56.40	2.00e-156	544.00
IUUC-Dno-029689	Dasypus novemcinctus	55.36	1.00e-152	531.00
IUUC-Dme-031976	Drosophila melanogaster	61.62	6.00e-174	602.00
IUUC-Eeu-035173	Erinaceus europaeus	41.26	9.00e-90	323.00
IUUC-Gma-043336	Glycine max	30.71	2.00e-23	103.00
IUUC-Hvu-047855	Hordeum vulgare	28.84	3.00e-21	95.90
IUUC-Lpe-051166	Leersia perrieri	29.32	1.00e-23	103.00
IUUC-Loc-052913	Lepisosteus oculatus	54.21	3.00e-160	556.00
IUUC-Mtr-058733	Medicago truncatula	31.95	5.00e-26	112.00
IUUC-Mmr-061480	Microcebus murinus	56.83	8.00e-156	541.00
IUUC-Mac-064539	Musa acuminata	29.53	1.00e-18	87.00
IUUC-Nle-069786	Nomascus leucogenys	53.94	5.00e-153	532.00
IUUC-Ont-072417	Oreochromis niloticus	54.79	1.00e-164	571.00
IUUC-Oba-075747	Oryza barthii	30.48	1.00e-22	101.00
IUUC-Obr-076676	Oryza brachyantha	29.48	4.00e-22	98.60
IUUC-Ogl-077366	Oryza glaberrima	30.48	6.00e-23	101.00
IUUC-Ogu-078229	Oryza glumaepatula	30.48	3.00e-22	100.00
IUUC-Ome-081788	Oryza meridionalis	30.50	2.00e-25	109.00
IUUC-Oni-082395	Oryza nivara	29.67	2.00e-22	100.00
IUUC-Ola-086419	Oryzias latipes	57.91	6.00e-161	558.00
IUUC-Pan-092732	Papio anubis	54.58	7.00e-154	535.00
IUUC-Psi-093899	Pelodiscus sinensis	55.13	6.00e-152	529.00
IUUC-Pma-094230	Petromyzon marinus	57.98	4.00e-158	549.00
IUUC-Pfo-096035	Poecilia formosa	54.60	1.00e-152	531.00
IUUC-Pop-099554	Populus trichocarpa	31.09	4.00e-24	105.00
IUUC-Ppe-102072	Prunus persica	34.12	2.00e-22	100.00
IUUC-Rno-105269	Rattus norvegicus	55.46	2.00e-151	527.00
IUUC-Smo-109331	Selaginella moellendorffii	29.71	7.00e-21	93.60
IUUC-Sit-109809	Setaria italica	29.56	3.00e-22	99.00
IUUC-Sly-111528	Solanum lycopersicum	31.34	2.00e-23	103.00
IUUC-Stu-112831	Solanum tuberosum	30.97	3.00e-22	99.40
IUUC-Sbi-114754	Sorghum bicolor	29.32	6.00e-23	100.00
IUUC-Tni-120512	Tetraodon nigroviridis	54.72	2.00e-166	577.00
IUUC-Tca-121389	Theobroma cacao	31.18	3.00e-23	102.00
IUUC-Tae-124630	Triticum aestivum	30.22	5.00e-22	98.20
IUUC-Tur-126824	Triticum urartu	30.34	9.00e-21	94.00
IUUC-Ttr-128817	Tursiops truncatus	55.46	6.00e-152	529.00
IUUC-Vvi-131057	Vitis vinifera	28.82	3.00e-24	105.00
IUUC-Xtr-132360	Xenopus tropicalis	51.80	9.00e-153	531.00
IUUC-Xma-133793	Xiphophorus maculatus	55.05	6.00e-153	532.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence