iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053445

UUCD1 version

UUC-LoA-00472

Ensembl Protein ID

ENSLAFP00000011585.3

UniProt Accession

G3TC32; G3TC32_LOXAF

Protein Name

Uncharacterized protein

Gene Name

FBXO7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000013837.3	ENSLAFT00000013836.3	ENSLAFP00000011585.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	78.54	0.00e+00	731.00	IUUC-Hsa-046348

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MKLRVRLQKR TWPLEMSEAE PTLGQLRAHL GQALLPTWGY SSDTRFAITL NNKDALTEDE 60
ETLASYGIVS GDLICLILED AIPAPNLPSS TDSEHSSLQN NDQPSLAASS NQSSIQDEQP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGCTTC GGGTCCGGCT TCAGAAGCGG ACCTGGCCGC TGGAGATGTC GGAAGCGGAG 60
CCGACGCTGG GGCAGCTGCG CGCGCATCTG GGCCAGGCCT TGTTGCCCAC TTGGGGGTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR021625--PI31_Prot_N

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF11566--PI31_Prot_N

Gene Ontology

GO:0097414--C:classical Lewy body
GO:0005829--C:cytosol
GO:0097409--C:glial cytoplasmic inclusion
GO:1990037--C:Lewy body core
GO:1990038--C:Lewy body corona
GO:0097462--C:Lewy neurite
GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0000422--P:mitophagy
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:2000134--P:negative regulation of G1/S transition of mitotic cell cycle
GO:0045620--P:negative regulation of lymphocyte differentiation
GO:1903204--P:negative regulation of oxidative stress-induced neuron death
GO:1903599--P:positive regulation of mitophagy
GO:0006626--P:protein targeting to mitochondrion
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0040012--P:regulation of locomotion
GO:0010975--P:regulation of neuron projection development
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001880	Ailuropoda melanoleuca	81.20	0.00e+00	655.00
IUUC-Atr-003003	Amborella trichopoda	26.28	1.00e-10	60.80
IUUC-Apl-003234	Anas platyrhynchos	66.67	6.00e-163	566.00
IUUC-Aca-004673	Anolis carolinensis	59.89	1.00e-149	522.00
IUUC-Ath-007055	Arabidopsis thaliana	24.83	1.00e-09	57.80
IUUC-Ame-011733	Astyanax mexicanus	42.13	2.00e-73	270.00
IUUC-Bta-013386	Bos taurus	79.54	0.00e+00	724.00
IUUC-Bdi-014029	Brachypodium distachyon	21.10	2.00e-03	37.00
IUUC-Bol-015733	Brassica oleracea	25.69	1.00e-06	47.80
IUUC-Cja-019301	Callithrix jacchus	81.23	0.00e+00	797.00
IUUC-Cfa-020474	Canis familiaris	80.88	0.00e+00	766.00
IUUC-Cpo-021958	Cavia porcellus	73.76	0.00e+00	740.00
IUUC-Csa-023971	Chlorocebus sabaeus	80.46	0.00e+00	750.00
IUUC-Cho-024677	Choloepus hoffmanni	85.77	5.00e-139	487.00
IUUC-Cin-025781	Ciona intestinalis	29.65	7.00e-44	171.00
IUUC-Csv-025989	Ciona savignyi	27.71	3.00e-22	98.60
IUUC-Dre-027820	Danio rerio	42.36	2.00e-36	146.00
IUUC-Dno-029936	Dasypus novemcinctus	76.08	0.00e+00	703.00
IUUC-Dor-030716	Dipodomys ordii	79.63	0.00e+00	645.00
IUUC-Ete-032853	Echinops telfairi	66.03	8.00e-124	437.00
IUUC-Eca-034267	Equus caballus	83.44	0.00e+00	677.00
IUUC-Eeu-035344	Erinaceus europaeus	79.44	2.00e-103	369.00
IUUC-Fca-035849	Felis catus	80.57	0.00e+00	748.00
IUUC-Fal-037612	Ficedula albicollis	62.45	3.00e-151	528.00
IUUC-Gmo-039634	Gadus morhua	49.08	6.00e-20	90.90
IUUC-Gga-041190	Gallus gallus	63.76	4.00e-168	584.00
IUUC-Gac-042001	Gasterosteus aculeatus	40.48	1.00e-66	247.00
IUUC-Gma-044390	Glycine max	25.10	4.00e-07	49.30
IUUC-Ggo-044544	Gorilla gorilla	79.12	0.00e+00	738.00
IUUC-Hsa-046348	Homo sapiens	78.54	0.00e+00	735.00
IUUC-Itr-048160	Ictidomys tridecemlineatus	81.90	0.00e+00	688.00
IUUC-Lch-049937	Latimeria chalumnae	54.92	2.00e-114	405.00
IUUC-Loc-052097	Lepisosteus oculatus	45.47	1.00e-87	316.00
IUUC-Meu-055942	Macropus eugenii	60.58	3.00e-136	478.00
IUUC-Mga-059897	Meleagris gallopavo	66.37	4.00e-119	421.00
IUUC-Mmr-061491	Microcebus murinus	84.32	0.00e+00	789.00
IUUC-Mdo-062549	Monodelphis domestica	71.16	0.00e+00	692.00
IUUC-Mmu-064312	Mus musculus	72.85	0.00e+00	751.00
IUUC-Mlu-067947	Myotis lucifugus	80.33	0.00e+00	668.00
IUUC-Nle-069189	Nomascus leucogenys	78.74	0.00e+00	726.00
IUUC-Opr-070340	Ochotona princeps	56.28	2.00e-54	206.00
IUUC-Ont-071633	Oreochromis niloticus	42.48	2.00e-84	306.00
IUUC-Oan-073153	Ornithorhynchus anatinus	67.56	3.00e-144	504.00
IUUC-Ocu-074367	Oryctolagus cuniculus	83.17	0.00e+00	636.00
IUUC-Oba-075835	Oryza barthii	22.22	4.00e-04	39.70
IUUC-Ola-087349	Oryzias latipes	40.69	1.00e-62	233.00
IUUC-Oga-088097	Otolemur garnettii	83.46	0.00e+00	765.00
IUUC-Oar-089633	Ovis aries	80.27	0.00e+00	728.00
IUUC-Ptr-091253	Pan troglodytes	78.35	0.00e+00	732.00
IUUC-Pan-092709	Papio anubis	80.46	0.00e+00	749.00
IUUC-Pma-094225	Petromyzon marinus	36.23	2.00e-64	239.00
IUUC-Ppa-095848	Physcomitrella patens	26.38	6.00e-06	45.80
IUUC-Pfo-096303	Poecilia formosa	41.86	1.00e-63	236.00
IUUC-Pab-098160	Pongo abelii	79.63	0.00e+00	670.00
IUUC-Pop-099047	Populus trichocarpa	24.54	2.00e-06	47.40
IUUC-Pca-100918	Procavia capensis	84.94	1.00e-149	523.00
IUUC-Ppe-101570	Prunus persica	23.28	5.00e-05	42.40
IUUC-Pva-103142	Pteropus vampyrus	81.74	0.00e+00	696.00
IUUC-Rno-105527	Rattus norvegicus	72.61	0.00e+00	739.00
IUUC-Sha-106501	Sarcophilus harrisii	68.51	4.00e-166	577.00
IUUC-Smo-108975	Selaginella moellendorffii	29.89	5.00e-03	33.50
IUUC-Sly-111386	Solanum lycopersicum	25.20	1.00e-07	51.20
IUUC-Stu-112530	Solanum tuberosum	25.62	2.00e-16	80.50
IUUC-Sar-113529	Sorex araneus	79.71	0.00e+00	692.00
IUUC-Ssc-116130	Sus scrofa	82.54	0.00e+00	772.00
IUUC-Tgu-116850	Taeniopygia guttata	62.17	3.00e-153	535.00
IUUC-Tru-117759	Takifugu rubripes	39.57	2.00e-70	259.00
IUUC-Tni-120308	Tetraodon nigroviridis	38.56	3.00e-57	215.00
IUUC-Tca-120980	Theobroma cacao	26.19	8.00e-12	65.10
IUUC-Tbe-127805	Tupaia belangeri	67.04	4.00e-146	511.00
IUUC-Ttr-129004	Tursiops truncatus	81.54	0.00e+00	718.00
IUUC-Vpa-130452	Vicugna pacos	83.20	0.00e+00	680.00
IUUC-Vvi-131289	Vitis vinifera	24.92	4.00e-07	49.70
IUUC-Xtr-132447	Xenopus tropicalis	47.80	2.00e-105	376.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence