iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-042461

Ensembl Protein ID

ENSGACP00000013499.1

UniProt Accession

G3P7C5; G3P7C5_GASAC

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000010180.1	ENSGACT00000013524.1	ENSGACP00000013499.1
ENSGACG00000010180.1	ENSGACT00000013527.1	ENSGACP00000013502.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-14	54.1	87	142

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L+++kG+  +++  ++++++W+++ + ++g  G +P+n+v+ ++
   Q: 87   FVALYDYEARTEDDLSFRKGERFQIL--NSTEGDWWEARSLTTGGTGYIPSNYVAPVD 142
           789***********************..8999**********************9987 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MGCVQCKDKE AAKLTDDRET SVSHNSGYRY GSDPTPQHYP SFGVTTIPNY NNFHSGATQG 60
VAVFGGVHTS SQSGTLRSRG GTGVTLFVAL YDYEARTEDD LSFRKGERFQ ILNSTEGDWW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCGACA GCAGCTCCCG AATCGGCAGG GACGGAAATC CCGCCGCTAT TCTCTCTTCA 60
TGCGACGGGA AAACTGTCAC AGGGAGCAGA AAAATATCCG CGATTCGCCA CACCAAAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002009	Ailuropoda melanoleuca	90.50	0.00e+00	1006.00
IUUC-Apl-003716	Anas platyrhynchos	84.97	0.00e+00	931.00
IUUC-Aca-005065	Anolis carolinensis	90.69	0.00e+00	1005.00
IUUC-Ame-011533	Astyanax mexicanus	96.92	0.00e+00	926.00
IUUC-Bta-012645	Bos taurus	90.50	0.00e+00	1004.00
IUUC-Cel-018682	Caenorhabditis elegans	57.91	2.00e-148	518.00
IUUC-Cja-019027	Callithrix jacchus	90.50	0.00e+00	1006.00
IUUC-Cfa-021163	Canis familiaris	90.50	0.00e+00	1006.00
IUUC-Cpo-022315	Cavia porcellus	90.50	0.00e+00	1006.00
IUUC-Csa-023721	Chlorocebus sabaeus	90.50	0.00e+00	1007.00
IUUC-Cho-025014	Choloepus hoffmanni	90.50	0.00e+00	1006.00
IUUC-Dre-027985	Danio rerio	94.04	0.00e+00	1067.00
IUUC-Dno-030043	Dasypus novemcinctus	75.84	0.00e+00	885.00
IUUC-Dor-031035	Dipodomys ordii	89.20	0.00e+00	985.00
IUUC-Dme-031976	Drosophila melanogaster	61.49	2.00e-166	578.00
IUUC-Eeu-034582	Erinaceus europaeus	87.90	3.00e-179	621.00
IUUC-Fca-035582	Felis catus	90.50	0.00e+00	1006.00
IUUC-Fal-037320	Ficedula albicollis	85.29	0.00e+00	936.00
IUUC-Gmo-038992	Gadus morhua	94.99	0.00e+00	1068.00
IUUC-Gga-041262	Gallus gallus	85.29	0.00e+00	936.00
IUUC-Ggo-044469	Gorilla gorilla	89.59	0.00e+00	1002.00
IUUC-Hsa-045723	Homo sapiens	90.50	0.00e+00	1007.00
IUUC-Itr-048519	Ictidomys tridecemlineatus	90.50	0.00e+00	1006.00
IUUC-Lch-049825	Latimeria chalumnae	89.39	0.00e+00	988.00
IUUC-Loc-052531	Lepisosteus oculatus	91.81	0.00e+00	1047.00
IUUC-Laf-053659	Loxodonta africana	90.50	0.00e+00	1006.00
IUUC-Mcc-055039	Macaca mulatta	84.69	0.00e+00	931.00
IUUC-Mga-060067	Meleagris gallopavo	90.71	0.00e+00	1005.00
IUUC-Mmr-061194	Microcebus murinus	90.50	0.00e+00	1006.00
IUUC-Mdo-062628	Monodelphis domestica	90.69	0.00e+00	1008.00
IUUC-Mmu-063896	Mus musculus	90.69	0.00e+00	1009.00
IUUC-Mpu-066333	Mustela putorius furo	90.69	0.00e+00	1008.00
IUUC-Mlu-067315	Myotis lucifugus	90.50	0.00e+00	1006.00
IUUC-Nle-068978	Nomascus leucogenys	85.10	0.00e+00	934.00
IUUC-Ont-072516	Oreochromis niloticus	97.77	0.00e+00	1103.00
IUUC-Oan-073714	Ornithorhynchus anatinus	93.63	0.00e+00	899.00
IUUC-Ocu-074284	Oryctolagus cuniculus	90.50	0.00e+00	1007.00
IUUC-Ola-087431	Oryzias latipes	97.02	0.00e+00	1095.00
IUUC-Oga-088789	Otolemur garnettii	84.92	0.00e+00	931.00
IUUC-Oar-089408	Ovis aries	90.50	0.00e+00	1004.00
IUUC-Ptr-091068	Pan troglodytes	90.50	0.00e+00	1007.00
IUUC-Pan-092217	Papio anubis	90.50	0.00e+00	1007.00
IUUC-Psi-093602	Pelodiscus sinensis	91.06	0.00e+00	1010.00
IUUC-Pfo-097084	Poecilia formosa	97.02	0.00e+00	1097.00
IUUC-Pab-097673	Pongo abelii	90.13	0.00e+00	1003.00
IUUC-Pca-100245	Procavia capensis	90.12	0.00e+00	907.00
IUUC-Pva-102645	Pteropus vampyrus	89.74	0.00e+00	978.00
IUUC-Rno-105372	Rattus norvegicus	90.69	0.00e+00	1008.00
IUUC-Sha-107637	Sarcophilus harrisii	90.69	0.00e+00	1002.00
IUUC-Sar-113016	Sorex araneus	79.89	0.00e+00	865.00
IUUC-Ssc-116389	Sus scrofa	90.32	0.00e+00	1005.00
IUUC-Tgu-117206	Taeniopygia guttata	85.29	0.00e+00	936.00
IUUC-Tru-118241	Takifugu rubripes	96.67	0.00e+00	1094.00
IUUC-Tni-120031	Tetraodon nigroviridis	97.39	0.00e+00	1095.00
IUUC-Tbe-127707	Tupaia belangeri	89.63	0.00e+00	909.00
IUUC-Ttr-129145	Tursiops truncatus	90.50	0.00e+00	1006.00
IUUC-Vpa-130815	Vicugna pacos	88.20	0.00e+00	954.00
IUUC-Xtr-132293	Xenopus tropicalis	84.73	0.00e+00	933.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence