iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120837

Ensembl Protein ID

ENSTNIP00000022483.1

UniProt Accession

H3DPN4; H3DPN4_TETNG

Protein Name

Histone-lysine N-methyltransferase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000019281.1	ENSTNIT00000022722.1	ENSTNIP00000022483.1
ENSTNIG00000019281.1	ENSTNIT00000003211.1	ENSTNIP00000002397.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.30e-19	68.6	1798	1857

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek...slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrs 53
           ++C++C++++ed++   +++eC +C++ +H++C kl+       ++lp+s +++C+kC +
   Q: 1798 NFCHICTKCYEDDEadaKMIECGRCHHRVHAKCEKLTddmyeLLSKLPESVAYTCTKCAE 1857
           79***********8889************************99***************86 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MAHSCRWRFP ARPGGSSNSG TGRRAGRTRV TASLRSVLGA HPNAAGLGPG FDAALQVSSV 60
IESNLQKFRD VLGESSDSSS GEEEPFRGFG TVAEQKRIQS PSTSSADTPS IQEKKPRGRP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCACA GCTGTCGGTG GCGGTTCCCC GCTCGGCCCG GAGGGAGCAG CAACTCCGGC 60
ACCGGGAGGA GAGCGGGCCG AACCAGGGTT ACTGCGTCTC TGCGGAGCGT CCTGGGAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR016569--MeTrfase_trithorax
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF02008--zf-CXXC

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD

Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002274	Ailuropoda melanoleuca	66.07	0.00e+00	1096.00
IUUC-Apl-003478	Anas platyrhynchos	67.72	0.00e+00	1095.00
IUUC-Aca-005086	Anolis carolinensis	63.32	0.00e+00	1123.00
IUUC-Ame-011195	Astyanax mexicanus	48.68	0.00e+00	992.00
IUUC-Bta-012974	Bos taurus	66.23	0.00e+00	1101.00
IUUC-Cja-019226	Callithrix jacchus	66.11	0.00e+00	1094.00
IUUC-Cfa-021049	Canis familiaris	66.27	0.00e+00	1099.00
IUUC-Cpo-021459	Cavia porcellus	65.99	0.00e+00	1083.00
IUUC-Csa-023434	Chlorocebus sabaeus	66.59	0.00e+00	1095.00
IUUC-Cho-024652	Choloepus hoffmanni	65.50	0.00e+00	896.00
IUUC-Csv-026268	Ciona savignyi	34.85	3.00e-123	436.00
IUUC-Cme-027224	Cyanidioschyzon merolae	36.25	7.00e-13	69.30
IUUC-Dre-028180	Danio rerio	68.86	0.00e+00	1136.00
IUUC-Dno-029583	Dasypus novemcinctus	46.18	0.00e+00	714.00
IUUC-Dor-030550	Dipodomys ordii	59.60	0.00e+00	885.00
IUUC-Ete-032834	Echinops telfairi	71.46	0.00e+00	687.00
IUUC-Eca-033615	Equus caballus	65.75	0.00e+00	1088.00
IUUC-Eeu-035136	Erinaceus europaeus	57.05	0.00e+00	714.00
IUUC-Fca-036311	Felis catus	48.39	0.00e+00	701.00
IUUC-Fal-037256	Ficedula albicollis	67.17	0.00e+00	1140.00
IUUC-Gmo-038641	Gadus morhua	60.57	0.00e+00	1517.00
IUUC-Gga-040828	Gallus gallus	67.55	0.00e+00	1112.00
IUUC-Gac-041452	Gasterosteus aculeatus	71.30	0.00e+00	3248.00
IUUC-Ggo-045124	Gorilla gorilla	63.19	0.00e+00	901.00
IUUC-Hsa-046143	Homo sapiens	66.23	0.00e+00	1096.00
IUUC-Itr-049024	Ictidomys tridecemlineatus	61.89	0.00e+00	1030.00
IUUC-Lch-049704	Latimeria chalumnae	64.53	0.00e+00	1091.00
IUUC-Loc-052181	Lepisosteus oculatus	68.42	0.00e+00	1217.00
IUUC-Laf-053946	Loxodonta africana	65.63	0.00e+00	1085.00
IUUC-Mcc-055508	Macaca mulatta	66.23	0.00e+00	1088.00
IUUC-Meu-056046	Macropus eugenii	47.80	0.00e+00	716.00
IUUC-Mga-059943	Meleagris gallopavo	67.73	0.00e+00	1104.00
IUUC-Mmr-061178	Microcebus murinus	66.19	0.00e+00	1095.00
IUUC-Mdo-063031	Monodelphis domestica	67.08	0.00e+00	1116.00
IUUC-Mmu-063650	Mus musculus	65.56	0.00e+00	1082.00
IUUC-Mpu-066495	Mustela putorius furo	66.27	0.00e+00	1095.00
IUUC-Mlu-068045	Myotis lucifugus	66.13	0.00e+00	1084.00
IUUC-Nle-069064	Nomascus leucogenys	65.99	0.00e+00	1091.00
IUUC-Opr-071043	Ochotona princeps	62.39	0.00e+00	992.00
IUUC-Ont-072556	Oreochromis niloticus	67.73	0.00e+00	1618.00
IUUC-Oan-073324	Ornithorhynchus anatinus	65.90	0.00e+00	1006.00
IUUC-Ocu-074190	Oryctolagus cuniculus	65.05	0.00e+00	1090.00
IUUC-Ola-087176	Oryzias latipes	66.24	0.00e+00	1531.00
IUUC-Oga-088208	Otolemur garnettii	65.95	0.00e+00	1085.00
IUUC-Oar-090152	Ovis aries	66.11	0.00e+00	1099.00
IUUC-Ptr-091127	Pan troglodytes	66.23	0.00e+00	1095.00
IUUC-Pan-092679	Papio anubis	66.47	0.00e+00	1088.00
IUUC-Psi-094059	Pelodiscus sinensis	65.89	0.00e+00	1108.00
IUUC-Pma-094258	Petromyzon marinus	50.59	1.00e-161	562.00
IUUC-Pfo-096536	Poecilia formosa	67.71	0.00e+00	3111.00
IUUC-Pab-098262	Pongo abelii	66.23	0.00e+00	1096.00
IUUC-Pca-100358	Procavia capensis	61.02	0.00e+00	940.00
IUUC-Pva-102522	Pteropus vampyrus	58.44	0.00e+00	888.00
IUUC-Rno-105200	Rattus norvegicus	65.10	0.00e+00	1081.00
IUUC-Sha-107174	Sarcophilus harrisii	64.48	0.00e+00	1130.00
IUUC-Sar-113289	Sorex araneus	44.88	1.00e-170	594.00
IUUC-Ssc-115509	Sus scrofa	48.44	0.00e+00	691.00
IUUC-Tgu-117047	Taeniopygia guttata	67.34	0.00e+00	1140.00
IUUC-Tru-118328	Takifugu rubripes	88.48	0.00e+00	6124.00
IUUC-Tsy-118953	Tarsius syrichta	64.24	2.00e-118	422.00
IUUC-Tbe-127950	Tupaia belangeri	65.10	0.00e+00	837.00
IUUC-Ttr-128643	Tursiops truncatus	63.92	2.00e-158	555.00
IUUC-Vpa-130660	Vicugna pacos	67.94	0.00e+00	927.00
IUUC-Xtr-132869	Xenopus tropicalis	59.52	0.00e+00	1020.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence