iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-034279

Ensembl Protein ID

ENSECAP00000006405.1

UniProt Accession

F6UCR0; F6UCR0_HORSE

Protein Name

Uncharacterized protein

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000007881.1	ENSECAT00000008541.1	ENSECAP00000006405.1
ENSECAG00000007881.1	ENSECAT00000008688.1	ENSECAP00000006532.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	8.70e-46	154.5	111	182

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktLvqkegWfrefl 73
           ++e ++ll++lq++++++L+v+dvldk+++  ll+ e+++++aaae++gn++++++LLk++vqke+Wf++fl
   Q: 111  HDECLQLLNLLQPTLVDRLLVRDVLDKCVAVDLLTLEDRNRIAAAENNGNESGVRELLKRIVQKENWFSTFL 182
           89********************************************************************96 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MANGYSTDKC FRYLISCFRA RVKKYIQVEP VLDYLTFLPP EAKEQVQTTA ATTGNMQAVE 60
LLLSTLEKGV WPPGWAREFV EALQRAGSPL AARYMNPELT DLPSPSFESA HDECLQLLNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCCACCAG TCCGTCTACT TGGGAGAATC CTCTCCCTTC TCTGAGAACG AAAGATGGCG 60
AATGGCTATT CCACAGACAA GTGTTTCCGC TATCTCATCT CGTGCTTCAG GGCCAGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

KEGG

ecb:100061257

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	83.66	0.00e+00	1645.00
IUUC-Apl-003900	Anas platyrhynchos	61.19	0.00e+00	1218.00
IUUC-Aca-005329	Anolis carolinensis	58.97	0.00e+00	1031.00
IUUC-Ang-009683	Aspergillus niger	37.14	1.30e-01	30.40
IUUC-Ame-011305	Astyanax mexicanus	47.77	0.00e+00	897.00
IUUC-Bta-012361	Bos taurus	85.42	0.00e+00	1633.00
IUUC-Cja-018760	Callithrix jacchus	85.09	0.00e+00	1602.00
IUUC-Cfa-020321	Canis familiaris	83.38	0.00e+00	1593.00
IUUC-Cpo-022450	Cavia porcellus	79.79	0.00e+00	1590.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	33.33	1.00e-12	68.60
IUUC-Csa-024194	Chlorocebus sabaeus	87.62	0.00e+00	1634.00
IUUC-Cho-024364	Choloepus hoffmanni	75.86	0.00e+00	1062.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	24.28	1.00e-24	109.00
IUUC-Dre-028305	Danio rerio	47.56	0.00e+00	806.00
IUUC-Dno-029831	Dasypus novemcinctus	85.07	0.00e+00	1655.00
IUUC-Dor-030410	Dipodomys ordii	76.80	0.00e+00	1212.00
IUUC-Ete-032950	Echinops telfairi	76.39	0.00e+00	660.00
IUUC-Eeu-034678	Erinaceus europaeus	79.98	0.00e+00	1588.00
IUUC-Fca-035618	Felis catus	86.47	0.00e+00	983.00
IUUC-Fal-037106	Ficedula albicollis	69.50	0.00e+00	1000.00
IUUC-Fso-038398	Fusarium solani	26.20	7.00e-30	126.00
IUUC-Gmo-038598	Gadus morhua	50.14	0.00e+00	690.00
IUUC-Gga-040467	Gallus gallus	60.63	0.00e+00	1192.00
IUUC-Gac-042316	Gasterosteus aculeatus	47.86	0.00e+00	853.00
IUUC-Ggo-045461	Gorilla gorilla	86.74	0.00e+00	1614.00
IUUC-Hsa-045771	Homo sapiens	86.65	0.00e+00	1614.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	83.04	0.00e+00	1580.00
IUUC-Lch-049913	Latimeria chalumnae	66.03	0.00e+00	930.00
IUUC-Loc-052768	Lepisosteus oculatus	53.94	0.00e+00	1022.00
IUUC-Laf-053933	Loxodonta africana	84.59	0.00e+00	1607.00
IUUC-Mcc-054695	Macaca mulatta	87.72	0.00e+00	1638.00
IUUC-Meu-056829	Macropus eugenii	74.15	0.00e+00	1139.00
IUUC-Mga-059205	Meleagris gallopavo	61.28	0.00e+00	1194.00
IUUC-Mmr-060703	Microcebus murinus	85.20	0.00e+00	1593.00
IUUC-Mdo-063079	Monodelphis domestica	72.33	0.00e+00	1462.00
IUUC-Mmu-064066	Mus musculus	78.86	0.00e+00	1597.00
IUUC-Mpu-066261	Mustela putorius furo	84.31	0.00e+00	1615.00
IUUC-Mlu-068196	Myotis lucifugus	84.96	0.00e+00	1619.00
IUUC-Nle-069479	Nomascus leucogenys	83.82	0.00e+00	1569.00
IUUC-Opr-070717	Ochotona princeps	76.64	0.00e+00	1173.00
IUUC-Ont-071702	Oreochromis niloticus	48.00	0.00e+00	887.00
IUUC-Oan-073639	Ornithorhynchus anatinus	66.49	0.00e+00	1206.00
IUUC-Ocu-074521	Oryctolagus cuniculus	84.78	0.00e+00	1650.00
IUUC-Ola-086351	Oryzias latipes	46.75	0.00e+00	837.00
IUUC-Oga-088539	Otolemur garnettii	81.46	0.00e+00	1574.00
IUUC-Oar-090186	Ovis aries	84.46	0.00e+00	1593.00
IUUC-Ptr-090575	Pan troglodytes	83.43	0.00e+00	1556.00
IUUC-Pan-092371	Papio anubis	87.82	0.00e+00	1639.00
IUUC-Psi-093072	Pelodiscus sinensis	64.65	0.00e+00	1292.00
IUUC-Pma-094345	Petromyzon marinus	43.96	5.00e-95	341.00
IUUC-Pfo-096401	Poecilia formosa	53.14	0.00e+00	691.00
IUUC-Pab-097623	Pongo abelii	86.45	0.00e+00	1632.00
IUUC-Pca-100993	Procavia capensis	78.46	0.00e+00	1322.00
IUUC-Pva-102227	Pteropus vampyrus	81.37	0.00e+00	1512.00
IUUC-Rno-105198	Rattus norvegicus	77.72	0.00e+00	1591.00
IUUC-Sha-107622	Sarcophilus harrisii	73.15	0.00e+00	1445.00
IUUC-Sar-113625	Sorex araneus	71.09	0.00e+00	762.00
IUUC-Tgu-117486	Taeniopygia guttata	60.16	0.00e+00	1140.00
IUUC-Tru-118445	Takifugu rubripes	46.29	0.00e+00	845.00
IUUC-Tsy-119512	Tarsius syrichta	82.65	0.00e+00	1509.00
IUUC-Tni-120711	Tetraodon nigroviridis	45.65	0.00e+00	872.00
IUUC-Tbe-127644	Tupaia belangeri	75.22	0.00e+00	1409.00
IUUC-Ttr-128989	Tursiops truncatus	79.77	0.00e+00	1597.00
IUUC-Vpa-130587	Vicugna pacos	79.52	0.00e+00	1276.00
IUUC-Xtr-132127	Xenopus tropicalis	53.70	0.00e+00	1042.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence