iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000000577.1	ENSORLT00000000713.1	ENSORLP00000000713.1
ENSORLG00000000577.1	ENSORLT00000000715.1	ENSORLP00000000715.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.50e-61	206.9	168	655

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+++l+l+       ++l++++++++   ++++l++lf+ ++ sk+k+v+p++ +++lk++ ++ s
   Q: 168  VGLKNVGNTCWFSAVIQSLFNLLEFQRLVLNysppARVHDLPRNQKEHRYLLFMQELRNLFSLMVGSKRKYVDPSRAVEILKDAFKS-S 255
           6******************************9666666666777667777799*****************************99998.9 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           +++qqD++Ef++ lld le+++                   +++ae+++ ++ k+++++lF g++    + +  +++ + +e f +++l
   Q: 256  ESQQQDVSEFTHKLLDWLEDAF-------------------QMKAEDREGERPKNPMVELFYGRFLAVGVLE--GKKFENTEMFGQYPL 323
           9*********************...................345678999****************777664..444556899****** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++ +     ++ +++++++lP+vL+++L+Rf+f+++ +++eki++k+efp +L +++
   Q: 324  QVNGFK-----DLHECLEAAMIEGEIES---LHSAENS--AKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPSMLYMDR 402
           ******.....9**************96...5555544..445899******************************************8 PP
   S: 264  fcts...................................................................................pe 269
             ++                                                                                   + 
   Q: 403  RHAHelrsksrtlqhslllsffslhsfrylsygsgpkrfpladvlqyamefasskpvctspvedidtsappggatgqqlappstaeqD- 490
           5555366666666666777777666666666666666666666666666666666666666666666666666666666665555550. PP
   S: 270  ekqke.................................................................................... 274
               +                                                                                    
   Q: 491  ----Sappqdssgpaaapaaapgpaqqqrvsvhkpftqsrlppdlpmhpaprhiteeelrvlegclhrwrsevendtrvldtxisrihr 575
           ....0555555555556666666666666666777777777777777777777777777777777777777777788888888888888 PP
   S: 275  ............kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                       ++ Y+L+av+vH+G+++ GHY+ay+++ +++ W++++D +Vt++++ee ++++      ++aY+l+Y 
   Q: 576  tielmysdksmmQVPYRLHAVLVHEGQANAGHYWAYIYDPHQHcWMKYNDISVTKSSWEELVRDSFggyrnASAYCLMYI 655
           888888888888***************************77777***************99997779************6 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MTVEQNVLQQ HSQKHQQTLL NQLREVTGTT DVQLLQQALQ VSNGDLAEAV AFLTEKNAKV 60
PQQDETTYYQ TSQVSNDRYI SVGSQADTNV IDLTGDDKDD LQRAIALSLE ESNRAFRETG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGATGAAG GAGGGGACGT CCTAGCCTCC GTGGATTTTC TTCAGCTGTT TGGTACCGAG 60
CGTGTTTCCC TCCCGGTCGA CGTTTTAGCG CGTTTCCGGC GTCTGCAGCG GCCATGACCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0009953--P:dorsal/ventral pattern formation
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001340	Ailuropoda melanoleuca	72.97	0.00e+00	1588.00
IUUC-Apl-004030	Anas platyrhynchos	74.22	0.00e+00	1661.00
IUUC-Aca-004753	Anolis carolinensis	59.85	0.00e+00	960.00
IUUC-Ani-009503	Aspergillus nidulans	33.02	5.00e-11	63.50
IUUC-Ame-010624	Astyanax mexicanus	77.69	0.00e+00	1246.00
IUUC-Bta-013166	Bos taurus	70.29	0.00e+00	1487.00
IUUC-Cja-019150	Callithrix jacchus	70.32	0.00e+00	1573.00
IUUC-Cfa-020649	Canis familiaris	70.37	0.00e+00	1569.00
IUUC-Cpo-021807	Cavia porcellus	72.38	0.00e+00	1629.00
IUUC-Csa-023388	Chlorocebus sabaeus	70.10	0.00e+00	1579.00
IUUC-Cho-024343	Choloepus hoffmanni	57.69	0.00e+00	749.00
IUUC-Cin-025302	Ciona intestinalis	35.37	2.00e-83	303.00
IUUC-Cgl-026575	Colletotrichum gloeosporioides	53.19	2.00e-10	61.60
IUUC-Dre-028016	Danio rerio	76.31	0.00e+00	1716.00
IUUC-Dno-029495	Dasypus novemcinctus	67.84	0.00e+00	1549.00
IUUC-Dor-030948	Dipodomys ordii	61.80	0.00e+00	1087.00
IUUC-Fca-035876	Felis catus	70.58	0.00e+00	1502.00
IUUC-Fal-036762	Ficedula albicollis	74.12	0.00e+00	968.00
IUUC-Gmo-039490	Gadus morhua	83.00	0.00e+00	1801.00
IUUC-Gga-040817	Gallus gallus	72.05	0.00e+00	1637.00
IUUC-Gac-042473	Gasterosteus aculeatus	86.29	0.00e+00	1879.00
IUUC-Ggo-044939	Gorilla gorilla	71.76	0.00e+00	1560.00
IUUC-Hsa-046204	Homo sapiens	70.57	0.00e+00	1524.00
IUUC-Itr-048276	Ictidomys tridecemlineatus	44.24	2.00e-154	539.00
IUUC-Lch-049572	Latimeria chalumnae	70.12	0.00e+00	1547.00
IUUC-Loc-052070	Lepisosteus oculatus	77.00	0.00e+00	1720.00
IUUC-Lma-053078	Leptosphaeria maculans	30.56	3.00e-11	64.70
IUUC-Laf-054426	Loxodonta africana	69.84	0.00e+00	1406.00
IUUC-Mcc-055858	Macaca mulatta	70.32	0.00e+00	1600.00
IUUC-Mga-059808	Meleagris gallopavo	72.32	0.00e+00	1582.00
IUUC-Mmr-060987	Microcebus murinus	70.43	0.00e+00	1555.00
IUUC-Mmu-064245	Mus musculus	69.59	0.00e+00	1513.00
IUUC-Mpu-066304	Mustela putorius furo	70.18	0.00e+00	1554.00
IUUC-Mlu-067139	Myotis lucifugus	70.40	0.00e+00	1538.00
IUUC-Nle-069075	Nomascus leucogenys	70.57	0.00e+00	1519.00
IUUC-Ont-072150	Oreochromis niloticus	83.26	0.00e+00	1915.00
IUUC-Oan-073054	Ornithorhynchus anatinus	68.61	0.00e+00	1478.00
IUUC-Ocu-074102	Oryctolagus cuniculus	68.36	0.00e+00	1554.00
IUUC-Oga-088939	Otolemur garnettii	70.39	0.00e+00	1491.00
IUUC-Oar-090266	Ovis aries	70.18	0.00e+00	1539.00
IUUC-Ptr-090546	Pan troglodytes	70.57	0.00e+00	1524.00
IUUC-Pan-092311	Papio anubis	70.23	0.00e+00	1599.00
IUUC-Psi-093459	Pelodiscus sinensis	78.76	0.00e+00	1016.00
IUUC-Pfo-096726	Poecilia formosa	86.03	0.00e+00	1325.00
IUUC-Pab-097608	Pongo abelii	72.66	0.00e+00	1576.00
IUUC-Pca-100718	Procavia capensis	65.16	0.00e+00	1083.00
IUUC-Pva-103150	Pteropus vampyrus	68.82	0.00e+00	1160.00
IUUC-Rno-105727	Rattus norvegicus	69.25	0.00e+00	1495.00
IUUC-Sha-107051	Sarcophilus harrisii	70.99	0.00e+00	1531.00
IUUC-Sar-113097	Sorex araneus	66.45	0.00e+00	1422.00
IUUC-Ssc-115877	Sus scrofa	68.09	0.00e+00	1486.00
IUUC-Tgu-117473	Taeniopygia guttata	69.24	0.00e+00	1498.00
IUUC-Tru-118135	Takifugu rubripes	74.52	0.00e+00	1594.00
IUUC-Tsy-119471	Tarsius syrichta	68.99	0.00e+00	1407.00
IUUC-Tni-120139	Tetraodon nigroviridis	71.52	0.00e+00	1471.00
IUUC-Tbe-127549	Tupaia belangeri	67.01	0.00e+00	1419.00
IUUC-Ttr-128887	Tursiops truncatus	46.71	0.00e+00	882.00
IUUC-Vda-129742	Verticillium dahliae	38.71	2.00e-10	62.00
IUUC-Vpa-130500	Vicugna pacos	68.12	0.00e+00	1466.00
IUUC-Xtr-132896	Xenopus tropicalis	70.10	0.00e+00	1547.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence