iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004557

UUCD1 version

UUC-AnC-00199

Ensembl Protein ID

ENSACAP00000010225.2

UniProt Accession

H9GGD8; H9GGD8_ANOCA

Protein Name

Uncharacterized protein

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000010427.2	ENSACAT00000010436.2	ENSACAP00000010225.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	81.44	2.00e-126	449.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

RMAGCGEIDH SINMLPTNKK TNESCSGAGP SLMVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGATGGCTG GCTGTGGTGA AATTGATCAT TCAATCAATA TGCTTCCAAC TAACAAGAAG 60
ACAAATGAAT CATGTTCCGG TGCAGGGCCA TCCCTTATGG TCCCTGAATG TGCTATTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	73.48	2.00e-129	455.00
IUUC-Apl-004143	Anas platyrhynchos	77.40	2.00e-132	465.00
IUUC-Ame-011088	Astyanax mexicanus	61.07	1.00e-82	299.00
IUUC-Bta-012639	Bos taurus	77.62	1.00e-129	455.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	5.00e-19	87.40
IUUC-Cja-019397	Callithrix jacchus	73.96	2.00e-128	451.00
IUUC-Cfa-021140	Canis familiaris	77.01	2.00e-133	468.00
IUUC-Cpo-021387	Cavia porcellus	75.42	1.00e-142	498.00
IUUC-Csa-023503	Chlorocebus sabaeus	80.50	4.00e-129	454.00
IUUC-Cho-024895	Choloepus hoffmanni	73.14	9.00e-111	392.00
IUUC-Cin-025455	Ciona intestinalis	53.21	8.00e-44	169.00
IUUC-Dre-028824	Danio rerio	47.83	7.00e-84	303.00
IUUC-Dno-029269	Dasypus novemcinctus	73.76	6.00e-131	460.00
IUUC-Dor-030592	Dipodomys ordii	76.24	3.00e-137	481.00
IUUC-Dme-031618	Drosophila melanogaster	58.00	5.00e-56	211.00
IUUC-Ete-032478	Echinops telfairi	74.72	2.00e-136	478.00
IUUC-Eca-033389	Equus caballus	78.09	1.00e-146	512.00
IUUC-Fca-035488	Felis catus	74.65	4.00e-132	463.00
IUUC-Fal-037087	Ficedula albicollis	85.59	2.00e-156	545.00
IUUC-Gmo-039713	Gadus morhua	34.09	5.00e-08	55.80
IUUC-Gga-040401	Gallus gallus	84.42	8.00e-139	486.00
IUUC-Gac-042412	Gasterosteus aculeatus	66.17	7.00e-87	313.00
IUUC-Ggo-045417	Gorilla gorilla	82.86	2.00e-127	448.00
IUUC-Hsa-045790	Homo sapiens	73.96	3.00e-128	451.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	76.88	8.00e-139	486.00
IUUC-Lch-049493	Latimeria chalumnae	68.73	4.00e-114	404.00
IUUC-Loc-052927	Lepisosteus oculatus	64.00	3.00e-101	361.00
IUUC-Laf-053904	Loxodonta africana	77.96	1.00e-134	472.00
IUUC-Mcc-055427	Macaca mulatta	78.12	4.00e-130	457.00
IUUC-Mmr-060580	Microcebus murinus	74.02	3.00e-128	451.00
IUUC-Mdo-062094	Monodelphis domestica	96.95	3.00e-77	279.00
IUUC-Mmu-063363	Mus musculus	75.90	3.00e-137	481.00
IUUC-Mpu-066816	Mustela putorius furo	73.41	6.00e-127	446.00
IUUC-Mlu-067433	Myotis lucifugus	76.24	4.00e-146	510.00
IUUC-Nle-068986	Nomascus leucogenys	77.56	3.00e-139	487.00
IUUC-Opr-071117	Ochotona princeps	39.44	3.00e-06	49.30
IUUC-Ont-072670	Oreochromis niloticus	78.16	9.00e-79	286.00
IUUC-Oan-073330	Ornithorhynchus anatinus	87.06	2.00e-106	378.00
IUUC-Ocu-074161	Oryctolagus cuniculus	75.99	7.00e-140	489.00
IUUC-Ola-086902	Oryzias latipes	61.82	2.00e-84	305.00
IUUC-Oga-089159	Otolemur garnettii	78.09	5.00e-148	516.00
IUUC-Oar-089586	Ovis aries	73.31	1.00e-120	426.00
IUUC-Ptr-090987	Pan troglodytes	73.96	3.00e-128	451.00
IUUC-Pan-091867	Papio anubis	78.18	8.00e-131	459.00
IUUC-Psi-094024	Pelodiscus sinensis	83.62	1.00e-144	505.00
IUUC-Pma-094453	Petromyzon marinus	63.31	6.00e-65	240.00
IUUC-Pfo-097108	Poecilia formosa	70.28	1.00e-83	303.00
IUUC-Pab-097997	Pongo abelii	72.85	1.00e-132	465.00
IUUC-Pca-100260	Procavia capensis	80.34	2.00e-134	471.00
IUUC-Pva-103140	Pteropus vampyrus	76.60	8.00e-136	476.00
IUUC-Rno-105795	Rattus norvegicus	75.84	3.00e-137	481.00
IUUC-Sha-107033	Sarcophilus harrisii	81.64	1.00e-145	508.00
IUUC-Ssc-116395	Sus scrofa	78.18	7.00e-150	523.00
IUUC-Tgu-116685	Taeniopygia guttata	84.66	2.00e-139	488.00
IUUC-Tru-118014	Takifugu rubripes	64.86	1.00e-83	302.00
IUUC-Tsy-119326	Tarsius syrichta	76.32	9.00e-147	512.00
IUUC-Tni-120322	Tetraodon nigroviridis	69.16	5.00e-82	297.00
IUUC-Tbe-128067	Tupaia belangeri	72.22	8.00e-137	479.00
IUUC-Ttr-128530	Tursiops truncatus	73.68	2.00e-132	465.00
IUUC-Vpa-130322	Vicugna pacos	74.79	2.00e-137	481.00
IUUC-Xtr-132606	Xenopus tropicalis	66.10	8.00e-117	412.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence