iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026794

Ensembl Protein ID

AAW42211

UniProt Accession

P0CP30; Q55VJ9; Q5KKN9; NPL4_CRYNJ

Genbank Protein ID

AAW42211.1

Protein Name

Nuclear protein localization protein 4

Genbank Nucleotide ID

AE017343

Gene Name

NPL4; CNC02370

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNC02370	AAW42211	AAW42211

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/NZF	29.12	4.00e-71	267.00	IUUC-Hsa-046334
UBD/ZnF/NZF	29.12	3.00e-70	263.00	IUUC-Mmu-063916
UBD/ZnF/Other	34.20	6.00e-106	380.00	IUUC-Sce-106145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cryptococcus neoformans

Functional Description
(View)

Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity).

Protein Sequence
(Fasta)

MLLRIRSPAG TARLTVQPET TGEDFAEAIL NTIPAADPQP DPATLALSNQ PGAAGESVPF 60
HALSGRTVGD MGFSHGDLLF LSYKPRAADP DSHPAMQATA PHPQPAQPDP SHPKTHTDPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAAGCC CCTGCCTCCC TGCGCGGCCA GCGCTGATCG CCGCAGCTGC TCCGGATCCG 60
CTCGCCCGCG GGGACTGCCC GCCTCACTGT GCAGCCCGAG ACGACGGGGG AGGACTTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0256--Endoplasmic reticulum
KW-0472--Membrane
KW-0509--mRNA transport
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0811--Translocation
KW-0813--Transport

Interpro

IPR016563--Npl4
IPR007717--NPL4_C
IPR007716--NPL4_Zn-bd_put

Pfam

PF05021--NPL4
PF05020--zf-NPL4

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0031965--C:nuclear membrane
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0043130--F:ubiquitin binding
GO:0031625--F:ubiquitin protein ligase binding
GO:0051028--P:mRNA transport
GO:0015031--P:protein transport
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cne:CNC02370

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000460	Aegilops tauschii	24.17	4.00e-07	47.40
IUUC-Aml-002268	Ailuropoda melanoleuca	30.03	3.00e-72	264.00
IUUC-Atr-002939	Amborella trichopoda	24.43	4.00e-04	37.40
IUUC-Apl-003496	Anas platyrhynchos	32.18	2.00e-68	251.00
IUUC-Aca-005230	Anolis carolinensis	27.73	4.00e-71	260.00
IUUC-Aly-005413	Arabidopsis lyrata	25.00	1.00e-04	38.90
IUUC-Ath-007051	Arabidopsis thaliana	25.29	2.00e-05	41.20
IUUC-Ago-007954	Ashbya gossypii	35.48	3.00e-97	347.00
IUUC-Acl-008208	Aspergillus clavatus	38.16	3.00e-119	420.00
IUUC-Afl-008574	Aspergillus flavus	40.38	4.00e-124	436.00
IUUC-Afu-008825	Aspergillus fumigatus	40.81	9.00e-129	452.00
IUUC-Ani-009495	Aspergillus nidulans	38.91	8.00e-124	435.00
IUUC-Ang-009762	Aspergillus niger	40.52	2.00e-124	437.00
IUUC-Aor-010199	Aspergillus oryzae	40.58	5.00e-123	432.00
IUUC-Ate-010592	Aspergillus terreus	40.14	1.00e-117	415.00
IUUC-Ame-011587	Astyanax mexicanus	23.45	1.00e-33	136.00
IUUC-Bgr-012124	Blumeria graminis	39.33	3.00e-124	437.00
IUUC-Bta-013312	Bos taurus	29.70	6.00e-75	273.00
IUUC-Bci-013648	Botrytis cinerea	39.69	1.00e-129	454.00
IUUC-Bdi-014326	Brachypodium distachyon	26.21	2.00e-06	45.10
IUUC-Bol-016294	Brassica oleracea	25.75	3.00e-06	44.30
IUUC-Bra-017023	Brassica rapa	25.75	4.00e-06	43.90
IUUC-Cel-018206	Caenorhabditis elegans	30.99	3.00e-62	230.00
IUUC-Cja-018869	Callithrix jacchus	31.72	9.00e-72	262.00
IUUC-Cfa-020757	Canis familiaris	29.70	2.00e-72	264.00
IUUC-Cpo-022390	Cavia porcellus	29.74	5.00e-70	256.00
IUUC-Csa-023366	Chlorocebus sabaeus	29.70	5.00e-74	270.00
IUUC-Cho-024455	Choloepus hoffmanni	28.98	6.00e-39	153.00
IUUC-Cin-025638	Ciona intestinalis	27.51	1.00e-37	149.00
IUUC-Csv-026310	Ciona savignyi	28.63	1.00e-42	165.00
IUUC-Cgl-026685	Colletotrichum gloeosporioides	37.93	3.00e-123	433.00
IUUC-Cme-027248	Cyanidioschyzon merolae	28.57	1.00e-02	32.70
IUUC-Dre-027689	Danio rerio	29.89	4.00e-74	270.00
IUUC-Dno-030004	Dasypus novemcinctus	30.27	4.00e-75	273.00
IUUC-Dor-030585	Dipodomys ordii	34.97	8.00e-67	246.00
IUUC-Dse-031202	Dothistroma septosporum	38.14	3.00e-115	406.00
IUUC-Dme-032092	Drosophila melanogaster	28.96	3.00e-65	241.00
IUUC-Ete-033009	Echinops telfairi	31.82	4.00e-20	90.50
IUUC-Eca-034001	Equus caballus	29.70	3.00e-74	270.00
IUUC-Eeu-034485	Erinaceus europaeus	26.88	3.00e-39	154.00
IUUC-Fca-036128	Felis catus	31.63	2.00e-70	258.00
IUUC-Fal-037523	Ficedula albicollis	29.12	4.00e-74	270.00
IUUC-Fox-037802	Fusarium oxysporum	40.97	7.00e-128	449.00
IUUC-Fso-038152	Fusarium solani	40.55	8.00e-129	452.00
IUUC-Gmo-038486	Gadus morhua	32.86	7.00e-70	256.00
IUUC-Ggr-039916	Gaeumannomyces graminis	39.52	3.00e-128	450.00
IUUC-Gga-041208	Gallus gallus	28.67	4.00e-73	267.00
IUUC-Gac-042304	Gasterosteus aculeatus	29.41	1.00e-66	245.00
IUUC-Gma-044007	Glycine max	25.00	1.00e-03	35.80
IUUC-Ggo-045236	Gorilla gorilla	28.47	3.00e-66	244.00
IUUC-Hsa-046334	Homo sapiens	28.98	1.00e-73	269.00
IUUC-Itr-047878	Ictidomys tridecemlineatus	39.01	2.00e-54	204.00
IUUC-Lch-050302	Latimeria chalumnae	28.12	9.00e-69	252.00
IUUC-Lpe-051362	Leersia perrieri	25.00	9.00e-08	49.70
IUUC-Loc-052548	Lepisosteus oculatus	29.89	8.00e-74	269.00
IUUC-Lma-053092	Leptosphaeria maculans	37.64	1.00e-117	415.00
IUUC-Laf-053911	Loxodonta africana	29.84	4.00e-74	270.00
IUUC-Mcc-055830	Macaca mulatta	31.78	1.00e-71	262.00
IUUC-Meu-056460	Macropus eugenii	28.57	3.00e-04	38.10
IUUC-Mor-057189	Magnaporthe oryzae	40.45	4.00e-129	453.00
IUUC-Mpo-057366	Magnaporthe poae	40.48	1.00e-130	458.00
IUUC-Mtr-057834	Medicago truncatula	25.58	1.70e-02	32.00
IUUC-Mla-059190	Melampsora laricipopulina	42.33	4.00e-156	543.00
IUUC-Mga-060036	Meleagris gallopavo	28.59	2.00e-72	264.00
IUUC-Mvi-060275	Microbotryum violaceum	42.61	2.00e-150	524.00
IUUC-Mmr-061300	Microcebus murinus	29.60	4.00e-73	267.00
IUUC-Mdo-062911	Monodelphis domestica	30.74	6.00e-71	259.00
IUUC-Mmu-063916	Mus musculus	30.92	4.00e-70	257.00
IUUC-Mac-065601	Musa acuminata	29.76	2.40e-02	31.20
IUUC-Mpu-065912	Mustela putorius furo	29.56	1.00e-72	265.00
IUUC-Mlu-067965	Myotis lucifugus	31.26	4.00e-72	263.00
IUUC-Nfi-068465	Neosartorya fischeri	40.23	2.00e-128	451.00
IUUC-Ncr-068936	Neurospora crassa	39.62	7.00e-125	439.00
IUUC-Nle-069570	Nomascus leucogenys	29.70	7.00e-74	269.00
IUUC-Opr-071097	Ochotona princeps	33.04	3.00e-59	220.00
IUUC-Ont-071430	Oreochromis niloticus	31.18	2.00e-77	281.00
IUUC-Oan-073709	Ornithorhynchus anatinus	28.09	3.00e-46	177.00
IUUC-Ocu-074875	Oryctolagus cuniculus	28.74	3.00e-65	241.00
IUUC-Oba-075214	Oryza barthii	24.90	4.00e-07	47.00
IUUC-Obr-076758	Oryza brachyantha	24.80	6.00e-07	46.20
IUUC-Ogl-077665	Oryza glaberrima	24.90	4.00e-07	47.00
IUUC-Ogu-078899	Oryza glumaepatula	24.90	4.00e-07	47.00
IUUC-Oin-079167	Oryza indica	24.90	4.00e-07	47.00
IUUC-Olo-080451	Oryza longistaminata	24.90	4.00e-07	47.00
IUUC-Ome-081836	Oryza meridionalis	24.90	6.00e-07	47.00
IUUC-Oni-083019	Oryza nivara	24.90	4.00e-07	47.00
IUUC-Opu-083122	Oryza punctata	24.90	2.00e-07	48.10
IUUC-Oru-084900	Oryza rufipogon	24.90	4.00e-07	47.00
IUUC-Osa-086054	Oryza sativa	24.90	4.00e-07	47.00
IUUC-Ola-087077	Oryzias latipes	28.49	1.00e-61	228.00
IUUC-Oga-088049	Otolemur garnettii	28.16	1.00e-54	206.00
IUUC-Oar-089678	Ovis aries	29.70	3.00e-75	274.00
IUUC-Ptr-091380	Pan troglodytes	31.90	1.00e-71	261.00
IUUC-Pan-092821	Papio anubis	29.74	3.00e-72	264.00
IUUC-Psi-093074	Pelodiscus sinensis	28.77	4.00e-73	266.00
IUUC-Pma-094102	Petromyzon marinus	29.45	7.00e-74	269.00
IUUC-Pno-094987	Phaeosphaeria nodorum	38.49	2.00e-120	424.00
IUUC-Ppa-095368	Physcomitrella patens	24.44	2.00e-07	48.10
IUUC-Pfo-097245	Poecilia formosa	33.16	2.00e-72	265.00
IUUC-Pab-098763	Pongo abelii	29.89	9.00e-74	269.00
IUUC-Pop-099355	Populus trichocarpa	25.00	1.70e-02	31.60
IUUC-Ppe-101990	Prunus persica	24.86	2.00e-03	35.00
IUUC-Pva-102308	Pteropus vampyrus	30.25	7.00e-57	213.00
IUUC-Pgr-103553	Puccinia graminis	43.39	4.00e-159	553.00
IUUC-Pte-104100	Pyrenophora teres	38.29	1.00e-118	418.00
IUUC-Pyt-104482	Pyrenophora triticirepentis	38.13	2.00e-117	414.00
IUUC-Rno-105582	Rattus norvegicus	30.97	4.00e-70	256.00
IUUC-Sce-106145	Saccharomyces cerevisiae	34.36	9.00e-106	375.00
IUUC-Sha-106647	Sarcophilus harrisii	31.09	2.00e-70	258.00
IUUC-Sja-107972	Schizosaccharomyces japonicus	38.19	5.00e-114	402.00
IUUC-Spo-108281	Schizosaccharomyces pombe	41.50	5.00e-112	395.00
IUUC-Ssl-108617	Sclerotinia sclerotiorum	39.40	4.00e-128	449.00
IUUC-Smo-108933	Selaginella moellendorffii	26.26	6.90e-02	29.60
IUUC-Sit-110083	Setaria italica	25.21	1.00e-07	48.90
IUUC-Sly-111645	Solanum lycopersicum	24.71	2.70e-02	31.20
IUUC-Stu-112422	Solanum tuberosum	25.00	2.60e-02	31.20
IUUC-Sbi-113987	Sorghum bicolor	25.79	5.00e-07	47.00
IUUC-Sre-115095	Sporisorium reilianum	46.10	4.00e-154	536.00
IUUC-Ssc-116141	Sus scrofa	30.55	1.00e-70	258.00
IUUC-Tgu-117492	Taeniopygia guttata	31.47	1.00e-65	241.00
IUUC-Tru-118463	Takifugu rubripes	30.75	2.00e-73	268.00
IUUC-Tsy-118993	Tarsius syrichta	27.68	2.00e-51	194.00
IUUC-Tni-119896	Tetraodon nigroviridis	32.62	4.00e-71	260.00
IUUC-Tca-121169	Theobroma cacao	25.30	1.00e-02	32.70
IUUC-Tre-122046	Trichoderma reesei	40.92	1.00e-129	454.00
IUUC-Tvi-122415	Trichoderma virens	39.39	8.00e-127	445.00
IUUC-Tae-123514	Triticum aestivum	24.71	5.00e-07	47.00
IUUC-Tme-127123	Tuber melanosporum	40.60	7.00e-130	455.00
IUUC-Tbe-127629	Tupaia belangeri	29.50	2.00e-32	131.00
IUUC-Ttr-128476	Tursiops truncatus	30.33	4.00e-56	210.00
IUUC-Uma-129492	Ustilago maydis	45.01	2.00e-157	547.00
IUUC-Vda-129702	Verticillium dahliae	38.08	1.00e-113	401.00
IUUC-Vvi-131090	Vitis vinifera	24.00	1.00e-03	35.80
IUUC-Xtr-131786	Xenopus tropicalis	31.14	7.00e-71	259.00
IUUC-Xma-133997	Xiphophorus maculatus	29.74	7.00e-73	266.00
IUUC-Yli-134537	Yarrowia lipolytica	37.30	4.00e-109	386.00
IUUC-Zma-134847	Zea mays	25.84	2.00e-07	48.10

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence